Biophysical Society 60th Annual Meeting

TRP Channels I (Boards B370 - B392)

1406-Pos Board B383 STRUCTURE OF A DOUBLE-KNOT TARANTULA TOXIN BOUND TO THE TRPV1 CHANNEL AT THE PROTEIN-LIPID INTERFACE. Chanhyung Bae , Claudio Anselmi, Jeet Kalia, Andres Jara-Oseguera, Charles D. Schwieters, Dmitriy Krepkiy, Chul Won Lee, Jae Il Kim, José D. Faraldo-Gómez, Kenton J. Swartz 1407-Pos Board B384 CELL UNROOFING ENHANCES TRPV1 MOBILITY IN THE PLASMA MEMBRANE. Eric N. Senning , Sharona E. Gordon 1408-Pos Board B385 TRPV1 EXPRESSED IN HEK293T/17 CELLS IS NOT REGULATED BY PLASMA MEMBRANE CHOLESTEROL CONTENT. Sharona E. Gordon , Marcus D. Collins, Moshe T. Gordon 1409-Pos Board B386 SEQUENTIAL EVENTS DURING CAPSAICIN-INDUCED TRPV1 ACTIVA- TION. Xian Xiao , Fan Yang, Jie Zheng 1410-Pos Board B387 TOLL-LIKE RECEPTOR 4 ACTIVATION BY LPS STIMULATES TRPV2 CHANNEL ACTIVITY IN MICROGLIA. Tuoxin Cao , Ian S. Ramsey 1411-Pos Board B388 ENGINEERING VANILLOID-SENSITIVITY INTO THE TRPV2 CHANNEL. Feng Zhang , Sonya M. Hanson, Larry Pearce, Dmitriy Krepkiy, Andres Jara-Oseguera, Peter M. Blumberg, Simon Newstead, Kenton J Swartz 1412-Pos Board B389 THE ROLE OF INTERACTING PROTEINS IN TRPV4 CHANNELOPATHIES.  Laura Vangeel , Sam Lievens, Jan Tavernier, Thomas Voets 1413-Pos Board B390 CPOW TRAVEL AWARDEE A LIPID-EXPOSED RESIDUE AT THE START OF S4-S5 LINKER CONTROLS TRPV4 GATING.  Jinfeng Teng , Stephen H. Loukin, Andriy Anishkin, Paul Blount, Ching Kung 1414-Pos Board B391 STUDYING THE EFFECTS OF BIOACTIVE LIPIDS ON TRPV4 ACTIVA- TION. Valeria Vasquez , Phanindra Velisetty, Julio F. Cordero-Morales 1415-Pos Board B392 CONVERSION OF THE PIP2 DEPENDENT TRPV6 CHANNEL FROM LOW TO HIGH PHOSPHOINOSITIDE AFFINITY BY A CHARGE REINTRODUCTION MUTATION. Phanindra Velisetty, Istvan Borbiro, Marina Kasimova, Luyu Liu, Vincenzo Carnevale, Tibor Rohacs Ligand-gated Channels I (Boards B393 - B416) 1416-Pos Board B393 EXPRESSION LEVEL DEPENDENCE OF THE GATING AND PERMEATION PROPERTIES OF P2X RECEPTOR CHANNELS. Mufeng Li , Shai D. Silberberg, Kenton J. Swartz 1417-Pos Board B394 MOLECULAR DETERMINANTS FOR LIGAND RECOGNITION IN P2X RECEP- TORS. Federica Gasparri , Stephan A. Pless 1418-Pos Board B395 ROLE OF G338 OF THE SECOND TRANSMEMBRANE DOMAIN IN GATING OF THE HUMAN P2X7 RECEPTOR. Nancy Zipfel, Achim Kless, Anja Pippel, Michaela Stolz, Guenther Schmalzing, Fritz Markwardt 1419-Pos Board B396 PLANT GLUTAMATE RECEPTORS: ELECTROPHYSIOLOGICAL CHARACTER- IZATION AND EVOLUTIONARY PERSPECTIVES. Erwan Michard , Michael M. Wudick, Michael A. Lizzio, Carlos Ortiz Ramírez, Cláudia Campos, José A. Feijó

1393-Pos Board B370 INFLUX-OPERATED CA 2+ ENTRY VIA PKD2-L1/PKD1-L3 CHANNELS FACILI- TATES SENSORY RESPONSES TO POLYMODAL TRANSIENT STIMULI. Yuxia Liu, Xiaodong Liu 1394-Pos Board B371 TEMPERATURE SENSITIVITY OF FRUIT FLY GUSTATORY RECEPTORS. Kayla Miguel , Autoosa Salari, Benjamin Zars, Troy Zars, Lorin S. Milescu, Mirela Milescu 1395-Pos Board B372 ROLES OF THE N- AND C-TERMINI IN THE FUNCTION OF THE YVC1P SAC- CHAROMYCES CEREVISIAE TRP CHANNEL. Samantha Ho, Lise Thomas 1396-Pos Board B373 MODULATION OF THERMO-TRP CHANNELS BY TEMPERATURE IN PLANAR LIPID BILAYERS. Mohamed Kreir , Matthias Beckler, Alison Obergrussberg- er, Ilka Rinke, Sonja Stoelze-Feix, Michael George, Andrea Brüggemann, Niels Fertig 1397-Pos Board B374 BROAD SENSITIVITY OF DROSOPHILA MELANOGASTER TRPA1 TO NOXIOUS CHEMICALS. Brett Boonen , Yeranddy Alpizar, Alessia Soldano, Alejandro Lopez Requena, Bassem Hassan, Thomas Voets, Karel Talavera 1398-Pos Board B375 PUNGENT AND NON-PUNGENT GENERAL ANESTHETICS INTERACT WITH TRPA1 VIA DISTINCT BINDING POCKET IN THE PORE DOMAIN RE- GION. Hoai T. Ton , Jacqueline Smith, Thieu X. Phan, Milton Brown, Gerard P. Ahern 1399-Pos Board B376 STRUCTURAL CHARACTERIZATION OF LIGAND-SPECIFIC INTERACTIONS IN TRPV1 CHANNEL: GATING MECHANISM BY CAPSAICIN AND CAPSAZ- EPINE. Fernando D. Gonzalez-Nilo , Javier Caceres-Molina, Felipe Bravo- Moraga, Romina Sepulveda, Ignacio Diaz-Franulic 1400-Pos Board B377 EXTRACELLULAR SODIUM IS REQUIRED FOR TEMPERATURE-DEPENDENT GATING IN TRPV1 CHANNELS. Andres Jara-Oseguera , Chanhyung Bae, Kenton J. Swartz 1401-Pos Board B378 A PAIN-INDUCING CENTIPEDE TOXIN TARGETS THE HEAT ACTIVATION MACHINERY OF NOCICEPTOR TRPV1. Shilong Yang, Fan Yang , Ningning Wei, Jing Hong, Bowen Li, Lei Luo, Mingqiang Rong, Vladimir Yarov-Yaro- voy, Jie Zheng, KeWei Wang, Ren Lai 1402-Pos Board B379 CYSTEINE-FREE MINITRPV1 IS A PLATFORM FOR STRUCTURE-FUNCTION ANALYSIS OF TRPV1. Mario G. Rosasco , Gilbert Q. Martinez, Erin M. Williams, Luke D. Cody, Sharona E. Gordon 1403-Pos Board B380 INHIBITION OF TRPV1 BY AN UNSATURATED FATTY ACID. Sara L. Morales- Lázaro , Itzel Llorente, Félix Sierra, Ana E. López-Romero, León D. Islas, Sidney A. Simon, Tamara Rosenbaum 1404-Pos Board B381 LIGHT-CONTROLLED PI3K ACTIVATION MIMICS TRPV1 POTENTIATION BY NGF. Anastasiia Stratiievska , Sharona E. Gordon 1405-Pos Board B382 SELECTIVE ACTIVATION OF NOCICEPTOR TRPV1 CHANNEL AND REVERSAL OF INFLAMMATORY PAIN IN MICE BY A NOVEL COUMARIN DERIVATIVE MURALATIN L FROMMURRAYA ALATA. Ningning Wei , Haining Lv, Yang Wu, Shilong Yang

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