Biophysical Society 60th Annual Meeting

2178-Pos Board B322 BLOCK OF RECOMBINANT T-TYPE CALCIUM CHANNELS BY GOSSYPOL, A POTENTIAL CONTRACEPTIVE. Osbaldo Lopez-Charcas , Zazil Herrera- Carrillo, Luis E. Montiel-Reyes, Juan C. Gomora 2179-Pos Board B323 THE ROLE OF CA2+ SIGNALING PROTEINS IN CAV1-MEDIATED EXCITA- TION-TRANSCRIPTION COUPLING. Nan Liu , Yaxiong Yang, Xiaodong Liu 2180-Pos Board B324 FUNCTIONAL ANALYSIS OF CAV1.1 L-TYPE CALCIUM CHANNELS EX- PRESSED IN TSA201 CELLS. Ulises Meza, Christin F. Romberg, Ong Moua, Kurt G. Beam, Roger A. Bannister 2181-Pos Board B325 ROTENONE, STIMULANT OF SUPEROXIDE RELEASE FROMMITOCHONDRI- AL COMPLEX I, TRANSIENTLY AUGMENTS L-TYPE CALCIUM CURRENT IN A7R5 ARTERIAL SMOOTH MUSCLE CELLS. Rikuo Ochi , Vidhi Dhagia, Dhara Patel, Michael S. Wolin, Sachin A. Gupte 2182-Pos Board B326 CAV1.2 INTERACTION WITH AT1R REDUCES RECEPTOR INTERNALIZA- TION. Tamara Hermosilla, Matias Encina, Cristian Moreno, Danna Morales, Edgardo Salamanca, Nayareth Hidalgo, Hilda Alfaro, Diego Varela 2183-Pos Board B327 POSTTRANSLATIONAL PROTEOLYTIC CLEAVAGE OF α2δ SUBUNITS: FUNCTIONAL IMPLICATIONS FOR HIGH VOLTAGE-GATED CALCIUM CHAN- NELS.  Ivan Kadurin , Simon Rothwell, Otto Meyer, Claudia Bauer, Leon Douglas, Annette Dolphin 2184-Pos Board B328 BIN1 REGULATES CAV1.2 CHANNEL CLUSTERING IN VENTRICULAR MYO- CYTES. Rose E. Dixon , Tingting Hong, Robin M. Shaw, Luis F. Santana 2185-Pos Board B329 MOLECULAR MIMICKING OF PHOSPHORYLATION AT S1928 AND S1700- T1704 CONFERS MODIFIED SURFACE TRAFFIC PROPERTIES TO CAV1.2 VOLTAGE GATED CALCIUM CHANNELS IN CULTURED HIPPOCAMPAL NEURONS. Alessandra Folci, Angela Steinberger, Ruslan Stanika, Marta Campiglio, Claudia Ramprecht, Gerald J. Obermair, Martin Heine, Valentina Di Biase 2186-Pos Board B330 THE β4 SUBUNIT OF L-TYPE CA2+ CHANNELS REGULATES TRANSCRIPTION OF ANTIVIRAL FACTORS IN A HEART CELL LINE. Eshwar R. Tammineni , Elba D. Carrillo, Ruben Soto, Antonio Angel-Ambrocio, Rosa M. Del Angel, Maria C. Garcia, Jorge A. Sanchez 2187-Pos Board B331 RAD IS AN AGENT OF SKELETAL MUSCLE ATROPHY. Donald Beqollari , Christin F. Romberg, Stefano Perni, Clara Franzini-Armstrong, Roger A. Board B332 ALPHA-ACTININ PROMOTES SURFACE LOCALIZATION AND ION CON- DUCTING ACTIVITY OF THE L-TYPE CA 2+ CHANNEL BY BINDING TO THE IQ REGION OF CAV1.2. Peter B. Henderson , Pang-Yen Tseng, Mark Lillya, Carlota Montagut-Bordas, Johannes W. Hell, Mary C. Horne 2189-Pos Board B333 DYNAMICAL EFFECTS OF THE SLOWLY ACTIVATING DELAYED RECTIFIER CURRENT ON VOLTAGE AND CALCIUM ALTERNANS IN CARDIAC MYOCYTES. Nathaniel-Georg S. Gutierrez , Daisuke Sato 2190-Pos Board B334 DIFFERENT ROLES OF IS4 AND IIS4 SEGMENTS IN CAV1.2 GATING.  Stanislav Beyl , Annette Hohaus, Stansislav Adranovits, Eugen Timin, Steffen Hering Bannister 2188-Pos

2191-Pos Board B335 CAV2.3 MEDIATE ATP RELEASE FROM RAT TAIL ARTERY SYMPATHETIC NERVES. Somayeh Mojard Kalkhoran , Damon Poburko, Jag Walia, Cynthia Gershome 2192-Pos Board B336 DIRECT INTERACTION BETWEEN N AND C TERMINI OF α1C SUBUNIT OF CAV1.2 L-TYPE CALCIUM CHANNEL. Adva Benmocha Guggenheimer, Lior Almagor , Vladimir Tsemakhovich, Debi Ranjan Tripathy, Joel Hirsch, Nathan Dascal 2193-Pos Board B337 HIGH THROUGHPUT PHARMACOLOGY OF CARDIAC L-TYPE CA 2+ CHANNELS: STABLE RECORDINGS OF CAV1.2 ON A HIGHLY PARALLEL AUTOMATED PATCH CLAMP SYSTEM. Markus Rapedius , Andrea Brug- gemann, Tom Goetze, Claudia Haarmann, Ilka Rinke, Sonja Stoelzle-Feix, Joerg Oestreich, Michael George, Niels Fertig 2194-Pos Board B338 EMINENCE OF VSD I IN THE VOLTAGE-DEPENDENT INACTIVATION OF THE HUMAN CA V 1.2 CHANNEL. Nicoletta Savalli , Marina Angelini, Antonios Pantazis, Taleh Yusifov, Alan Neely, Riccardo Olcese 2195-Pos Board B339 CROSSTALK BETWEEN BETA SUBUNITS, INTRACELLULAR CA 2+- SIGNALING AND SNARES IN THE MODULATION OF CAV2.1 CHANNEL STEADY-STATE INACTIVATION. Selma A. Serra, Gemma G. Gené, Miguel A. Valverde, Jose M. Fernandez-Fernandez 2196-Pos Board B340 REGULATION OF VOLTAGE SENSING STRUCTURES OF CAV1.2 CALCIUM CHANNELS BY THE AUXILIARY β-SUBUNIT (β3). Daniela De Giorgis , Gustavo Contreras, Nicoletta Savalli, Nieves Navarro-Quezada, Carlos Gonzalez, Riccardo Olcese, Alan Neely 2197-Pos Board B341 VOLTAGE-SENSOR PHARMACOLOGY OF CALCIUM CHANNELS. Autoosa Salari , Brooklynn R. White, Timothee Pale, Vincent Baggett, Mirela Milescu Ion Channels, Pharmacology, and Disease (Boards B342 - B377) 2198-Pos Board B342 WHAT TYPE OF ION CHANNELS ARE IDENTIFIED ON OSTEOSARCOMA CELLS MEMBRANE? Maria B. Seabra , Juliana P. Aguiar, Wyndly Daniel C. Gaião, Reginaldo P. Silva, Claúdio Gabriel Rodrigues 2199-Pos Board B343 INTERNATIONAL TRAVEL AWARDEE THE PATHOGENIC A116V MUTATION ENHANCES THE SELECTIVE ION- CHANNEL ACTIVITY AND TOXICITY OF THE PRION PROTEIN IN LIVING CELLS. Sabareesan Ambadi Thody 2200-Pos Board B344 DIVALENT COPPER COMPLEXES AS INFLUENZA A M2 S31N BLOCK- ERS. Kelly L. McGuire , Spencer Wallentine, Nathan A. Gordon, Greg Mohl, Mckay D. Jensen, Roger Harrison, David D. Busath 2201-Pos Board B345 OBSERVATION OF PARTIAL AND COMPLETE BLOCK BY AMANTADINE AND RIMANTADINE IN INFLUENZA A M2 S31N BY ELECTROPHYSIOLOGY METHODS. Kelly L. McGuire , Mitchell L. Gleed, David D. Busath 2202-Pos Board B346 EPR AND ELECTRON MICROSCOPY STUDY OF THE INFLUENZA A M2 TRANSMEMBRANE DOMAIN ASSEMBLY AND DRUG RESPONSE. Elka R. Georgieva , Peter P. Borbat, Kirill Grushin, Svetla Stoilova-McPhie, Nichita J. Kulkarni, Zhichun Liang, Jack H. Freed

T U

E S

D A Y

119