Biophysical Society 61st Annual Meeting | Program Guide

Platform Intrinsically Disordered Proteins (IDP) and Aggregates I 8:15 am - 10:15 am, Room 206/207

1559-Plat 8:45 am REVEALING THE MECHANISM OF BINDING SELECTIVITY IN UNDECAPRE- NYL DIPHOSPHATE SYNTHASE.  Fareeha Kanwal , Donald Jacobs 1560-Plat 9:00 am DYNAMIC FLEXIBILITY INDEX SHEDS LIGHT ON PIN1 ALLOSTERY.  Paul Campitelli , Huan-Xiang Zhou, Giovanna Ghirlanda, S. Banu Ozkan 1561-Plat 9:15 am INTRINSIC DISORDERED CONTROLS TRANSCRIPTION OF BACTERIAL TOXIN-ANTITOIXN MODULES.  Abel Garcia-Pino 1562-Plat 9:30 am INTEGRATED VIEW OF INTERNAL FRICTION IN UNFOLDED PROTEINS FROM SINGLE-MOLECULE FRET, CONTACT QUENCHING, THEORY, AND SIMULATIONS.  Andrea Soranno , Andrea Holla, Fabian Dingfelder, Daniel Nettels, Dmitrii E. Makarov, Benjamin Schuler 1563-Plat 9:45 am ESCAPING THE WATER CAGE: PROTEIN INTRAMOLECULAR VIBRATIONS AND THE DYNAMICAL TRANSITION. Mengyang Xu , Katherine A. Niessen, Yanting Deng, Nigel S. Michki, Andrea G. Markelz 1564-Plat 10:00 am FACILITATOR MODELS OF WEAK BINDING IN PROTEIN-PROTEIN INTERAC- TIONS.  Seyit Kale , Madeleine Strickland, Alan Peterkofsky, Nico Tjandra, Jian Liu Subgroup Chairs Meeting Your written application materials are typically the only information a search committee will have before them as they make the vast majority of cuts. Learn how to craft credentials that speak clearly and powerfully on your behalf, and help committees understand the potential contribu- tion you have to offer. Exhibits 10:00 am - 4:30 pm, Hall B-2 & C Coffee Break 10:15 am - 11:00 am, Hall B-2 & C Symposium Awards 10:45 am - 12:45 pm, Great Hall A Chair Suzanne Scarlata, Worcester Polytechnic Institute No Abstract 10:45 am Margaret Oakley Dayhoff Award UNDERSTANDING MOLECULAR-SCALE BIOPHYSICS IN CELLS WITH SINGLE-MOLECULE IMAGING. Julie Biteen No Abstract 11:02 am Michael and Kate Barany Award THE MECHANISM OF DYNEIN MOTILITY. Ahmet Yildiz 9:00 am - 10:30 am, Room 222 Career Center Workshop Demystifying the Academic Job Search III: Pre- paring Your Written Application Materials: CV, Cover Letter, and Research Statement 9:30 am - 10:30 am, Room 212/213

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Co-Chairs Alex Holehouse, Washington University in Saint Louis Joshua Riback, University of Chicago 1549-Plat 8:15 am

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RESOLVING THE CONTROVERSY BETWEEN SAXS AND FRET MEASURE- MENTS ON UNFOLDED PROTEINS. Wenwei Zheng , Alessandro Borgia, Alexander Grishaev, Benjamin Schuler, Robert B. Best 1550-Plat 8:30 am SIMULATIONS AND EXPERIMENTS PROVIDE A CONVERGENT VIEW OF PROTEIN UNFOLDED STATES UNDER FOLDING CONDITIONS.  Alex S. Holehouse , Ivan Perana, Isaac S. Carrico, Osman Bilsel, Daniel P. Raleigh, Rohit V. Pappu 1551-Plat 8:45 am BIOPHYSICAL STUDIES OF THE INTERACTION BETWEEN OPTIMIZED PEP- TIDES AND AMYLOID-BETA ELUCIDATE A COMPLETELY NOVEL BINDING MODE.  Tamar Ziehm , Antonia Klein, Janine Kutzsche, Dieter Willbold 1552-Plat 9:00 am SINGLE MOLECULE FRET INVESTIGATION OF THE DIMENSIONS AND DY- NAMICS IN HIGHLY COOPERATIVE SIC1-WD40 BINDING.  Gregory Gomes , Veronika Csizmok, JIanhui Song, Hue-Sun Chan, Julie Forman-Kay, Claudiu C. Gradinaru 1553-Plat 9:15 am MEASURING THE (GOOD) SOLVENT QUALITY OF WATER FOR DISOR- DERED PROTEINS FROM A SINGLE SAXS MEASUREMENT.  Joshua A. Riback , Micayla A. Bowman, Adam Zmyslowski, Catherine R. Knoverek, John Jumper, James Hinshaw, Emily B. Kaye, Karl F. Freed, Patricia L. Clark, Tobin R. Sosnick 1554-Plat 9:30 am RIGID SPIN LABELS FOR IMPROVED DISTANCE AND DYNAMICS IN IN- TRINSICALLY DISORDERED PROTEINS AND PEPTIDES.  Enrico Zurlo, Nico J. Meeuwenoord, Dmitri V. Filippov, Martina Huber 1555-Plat 9:45 am EXAMINATION OF THE OLIGOMERIZATION MECHANISM OF SOD1 IN VITRO AND IN LIVE CELLS.  Brian C. Mackness, Noah R. Cohen, C. Robert Matthews, Jill A. Zitzewitz, Osman Bilsel 1556-Plat 10:00 am EXPLORING THE FUNCTIONAL AND STRUCTURAL IMPACT OF DISEASE- ASSOCIATED MUTANTS OF TAU.  Ana M. Melo , Elizabeth Rhoades Platform Protein Dynamics and Allostery II 8:15 am - 10:15 am, Room 208/209 Co-Chairs Abel Garcia-Pino, Université Libre de Bruxelles, Belgium Seyit Kale, NIH 1557-Plat 8:15 am CID Travel Awardee PREDICTING RESIDUES THAT INCREASE ANTIBIOTIC RESISTANCE OF CTX- M9 ENZYMES USING MOLECULAR SIMULATION AND STATISTICAL LEARN- ING.  George A. Cortina , Malgorzata J. Latallo, Peter M. Kasson 1558-Plat 8:30 am MODELING PROTEINS’ HIDDEN CONFORMATIONS TO PREDICT ANTIBI- OTIC RESISTANCE.  Gregory Bowman

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