Biophysical Society 61st Annual Meeting | Program Guide

1594-Plat 12:00 pm EMERGING ROLE OF THE MITOCHONDRIAL OUTER MEMBRANE TRANS- LOCATOR PROTEIN (TSPO) IN HEART FAILURE AND MITOCHONDRAI QUALITY CONTROL.  Phung N. Thai, Daniel Daugherty, Bert J. Frederich, Samuel Galice, Wenbin Deng, Donald M. Bers, Saul Schaefer, Elena N. 12:15 pm DYSREGULATION OF MITOCHONDRIAL PERMEABILITY TRANSITION PORE (MPTP) IS ASSOCIATED WITH ENHANCED ROS PRODUCTION IN SKELETAL MUSCLE OF AN ALS MOUSE MODEL.  Yajuan Xiao , Jianxun Yi, Chehade Karam, Xuejun Li, Kamal Dhakal, Dosuk Yoon, Jingsong Zhou 1596-Plat 12:30 pm AN ALTERNATIVE SPLICE VARIANT OF CHLORIDE INTRACELLULAR CHAN- NEL 5 PROTEIN, (CLIC5B) REGULATES CARDIAC MITOCHONDRIAL LOCAL- IZATION AND FUNCTION OF CLIC5.  Devasena Ponnalagu , Ahmed Tafsirul Hussain, Shubha Gururaja Rao, Harpreet Singh Platform General Protein-Lipid Interactions II 10:45 am - 12:45 pm, Room 206/207 Co-Chairs Jeanne Stachowiak, University of Texas at Austin James Sturgis, LISM - CNRS/AMU, France 1597-Plat 10:45 am LIPID PERTURBATION BY MEMBRANE PROTEINS AND THE LIPOPHOBIC EFFECT.  Jean-Pierre Duneau, Jon Khao, James N. Sturgis 1598-Plat 11:00 am THE MYRISTOYL MODIFICATION OF C-SRC ALTERS THE LATERAL ORGA- NIZATION OF HOST HETEROGENOUS RAFT-LIKE MEMBRANES. Mridula Dwivedi , TomMejuch, Herbert Waldmann, Roland Winter 1599-Plat 11:15 am THE USE OF FLUORESCENTLY LABELED LIPIDS TO DETERMINE DYNAM- ICS OF PROTEIN MEDIATED IN VITRO LIPID TRANSFER. Max Lönnfors , Aby Grabon, Kaitlyn R. McGrath, Ashutosh Tripathi, Marta G. Lete, Pentti Somerharju, Vytas A. Bankaitis 1600-Plat 11:30 am PI(4,5)P 2 CLUSTERING BY THE EBOLA VIRUS MATRIX PROTEIN VP40.  Jeevan B. GC , Bernard S. Gerstman, Prem P. Chapagain 1601-Plat 11:45 am INTERACTION OF PH DOMAINS WITH PHOSPHATIDYLINOSITOL PHOS- PHATES: STRUCTURES AND ENERGETICS BY SIMULATION.  Fiona B. Naughton , Antreas C. Kalli, Mark S P Sansom 1602-Plat 12:00 pm RUNNING AGAINST TIME - A KINETIC LIMIT FOR ENDOPHILIN ACTION DURING RAPID ENDOCYTOSIS.  Kumud Raj Poudel, Hang Yu, Klaus Schul- ten, Jihong Bai 1603-Plat 12:15 pm OPTOGENETIC CONTROL OF MEMBRANE TETHERING AND INTER-MEM- BRANE COMMUNICATIONS.  Ji Jing , Lian He, Yubin Zhou 1604-Plat 12:30 pm MEMBRANE FISSION BY PROTEIN CROWDING. Wilton Snead, Carl Hayden, Avinash Gadok, Padmini Rangamani, Jeanne Stachowiak Dedkova 1595-Plat

1583-Plat 11:15 am INSIGHTS INTO THE DYNAMICS OF THE HIV-1 ENV GLYCAN SHIELD.  Thomas Lemmin , Cinque Soto, Peter D. Kwong 1584-Plat 11:30 am WE CAN PREDICT THE EFFECTS OF KINASE DOMAIN MUTATIONS USING MOLECULAR DYNAMICS AND MACHINE LEARNING.  E. Joseph Jordan , Ravi Radhakrishnan 1585-Plat 11:45 am LARGE SCALE MOLECULAR DYNAMICS SIMULATIONS OF THREE CLAS- SICAL CADHERINS INVOLVED IN CELL ADHESION.  Brandon Neel , Collin Nisler, Raul Araya-Secchi, Marcos Sotomayor 1586-Plat 12:00 pm TOWARDS A RATIONAL DESIGN OF MACROLIDE ANTIBIOTICS IN ORDER TO COMBAT BACTERIAL RESISTANCE.  Anna Pavlova , Jerry M. Parks, Adegboyega K. Oyelere, James C. Gumbart 1587-Plat 12:15 pm FAST FORWARD PROTEIN FOLDING. Maxwell I. Zimmerman , Gregory R. 12:30 pm TEMPERATURE DYNAMICS OF SINGLE MOLECULAR ANTIFREEZE PROTEIN. Rio Okada , Tatsuya Arai, Daichi Fukami, Yuhuku Matsushita, Jae-won Chang, Hiroshi Sekiguchi, Noboru Ohta, Tadashi Mori, Masaki Nishijima, Keisuke Miyazawa, Takeshi Fukuma, Keigo Ikezaki, Sakae Tsuda, Yuji C. Sasaki Platform Mitochondria in Cell Life and Death 10:45 am - 12:45 pm, Room R08/09 Co-Chairs Devasena Ponnalagu, Drexel University College of Medicine Veronica S. Eisner, University of Chile 1589-Plat 10:45 am CHARCOT-MARIE-TOOTH TYPE2A MFN2 DOMAIN-SPECIFIC MUTANTS DEFERENTIALLY ALTER MITOCHONDRIAL FUSION DYNAMICS AND MOTIL- ITY.  Veronica Eisner , Diego Troncoso, Pamela Rojas, Josefa Vial, Mauricio Castro, Sergio Henríquez, Rita Horvath 1590-Plat 11:00 am YEAST VDAC2 HAS PORE FORMING ACTIVITY: FUNCTIONAL CONSE- QUENCES. Maria Carmela Di Rosa, Andrea Magri, Simona Reina, Vito De Pinto 1591-Plat 11:15 am OXIDATIVE STRESS INDUCED BY VDAC OPENING IN CANCER CELLS DE- PENDS ON CYTOSOLIC FREE TUBULIN AND IS BLOCKED BY ROS SCAVENGING AND SUPPRESSION OF SUPEROXIDE FORMATION BY COMPLEX III.  Diana Fang, Kareem Hes- lop, Morgan Morris, David DeHart, Monika Beck Gooz, John J. Lemasters, Eduardo N. Maldonado 1592-Plat 11:30 am MANIPULATION OF AMYLOID PRECURSOR PROTEIN PROCESSING IMPACTS BRAIN BIOENERGETICS AND GLUCOSE METABOLISM.  John A. Findlay , D. Lee Hamilton, Sarmi Sri, Mariana Vargas-Caballero, Michael L J Ashford, Peter J S Smith 1593-Plat 11:45 am MITOCHONDRIAL NM23-H4/NDPK-D AND OPA1: PARTNERS IN SHAPING MITOCHONDRIA AND INITIATING MITOPHAGY?  Uwe Schlattner , Céline Desbourdes, Małgorzata Tokarska-Schlattner, Valerian E. Kagan Bowman 1588-Plat

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