Biophysical Society 62nd Annual Meeting | Program Guide

2356-Pos Board B372 OBSERVING THE MOVEMENT OF HETEROGENEOUS VOLTAGE SENSING DOMAINS VIA INTERMOLECULAR FRET. Lee Min Leong , Bok Eum Kang, Bradley J. Baker 2357-Pos Board B373 TRACKING OF THE R1 OF THE S4 DURING VOLTAGE SENSOR DEACTIVA- TION UNDER IMPROVED OPTICAL CONDITIONS. Elizabeth E. L. Lee , Michael F. Priest, Francisco Bezanilla 2358-Pos Board B374 THE ROLE OF BACKBONE HYDROGEN BONDS IN THE VOLTAGE SENSOR OF K + CHANNELS. Daniel T. Infield, Kimberly Matulef , Jason D. Galpin, Christopher A. Ahern, Francis I. Valiyaveetil 2359-Pos Board B375 EXPLORING POSSIBLE CONVERSION BETWEEN ALPHA- AND 3 10 -HELIX IN S4 OF SHAKER POTASSIUM CHANNEL. Carlos Alberto Z. Bassetto Junior , João L. Carvalho-de-Souza, Francisco Bezanilla 2360-Pos Board B376 DETERMINING THE TARGET OF MEMBRANE STEROLS ON THE GATING OF VOLTAGE-GATED POTASSIUM CHANNELS USING VOLTAGE-CLAMP FLUO- ROMETRY. Zakany Florina, Ferenc Papp, Gyorgy Panyi, Zoltan Varga 2361-Pos Board B377 FUNCTIONAL ANALYSIS OF THE VOLTAGE SENSOR DOMAIN PRESENT IN THE MAMMALIAN SPERM-SPECIFIC NA + /H + EXCHANGER BY PATCH- CLAMP FLUOROMETRY OF CHIMERIC FLUORESCENT VOLTAGE SEN- SOR. César Arcos Hernández , Esteban Suarez, León Islas, Takuya Nishigaki 2362-Pos Board B378 SITE-SPECIFIC ENCODING OF CITRULLINE, A NEUTRAL ANALOG OF ARGI- NINE, TO STUDY THE ATOMIC BASIS FOR VOLTAGE-DEPENDENT GATING IN ION CHANNELS. Daniel T. Infield , Jason D. Galpin, Grace D. Galles, Christopher A. Ahern 2363-Pos Board B379 USING UNNATURAL amINO ACIDS TO PROBE THE INTERACTION BE- TWEEN TARANTULA TOXINS AND VOLTAGE SENSING DOMAINS IN KV CHANNELS. Kanchan Gupta , Kenton J. Swartz 2364-Pos Board B380 ORTHOGONALITY OF A SYNTHETIC PYRROLYSINE TRNA IN THE XENOPUS OOCYTE AND ITS USE TO ENCODE UNNATURAL amINO ACIDS INTO ION CHANNELS. Daniel T. Infield , John D. Lueck, Jason D. Galpin, Grace D. Galles, Christopher A. Ahern 2365-Pos Board B381 COMBINING ELECTRICAL AND OPTICAL MEASUREMENTS TO REVEAL THE STRUCTURE-FUNCTION RELATIONSHIP OF VOLTAGE-GATED POTASSIUM CHANNELS. Corianne VandenAkker , Steven Boxer 2366-Pos Board B382 RECONSTITUTION OF VOLTAGE-ACTIVATED POTASSIUM CHANNEL INTO PHOSPHOLIPID BILAYER. Chanhyung Bae , Swartz J. Kenton 2367-Pos Board B383 IMAGING VOLTAGE GATING OF ENDOGENOUS NEURONAL ION CHAN- NELS WITH FLUORESCENT TARANTULA TOXIN. Parashar Thapa , Rebecka Sepela, Robert Stewart, Mark Lillya, Oscar Vivas, Laxmi Parajuli, Sebastian Fletcher-Taylor, Karen Zito, Bruce E. Cohen, Jon Sack 2368-Pos Board B384 LIPID-DEPENDENT ACTIVATION AND DESENSITIZATION MECHANISM OF MTHK. Nattakan Sukomon , Crina Nimigean

2343-Pos Board B359 IN SILICO ASSESSMENT OF ATRIAL FIBRILLATION-SELECTIVITY OF IKUR INHIBITORS: ROLE OF VARIABILITY IN DISEASE-ASSOCIATED REMODEL- ING. Nicholas Ellinwood , Dobromir Dobrev, Stefano Morotti, Eleonora Grandi 2344-Pos Board B360 FACILITATION BY HERG CHANNEL BLOCKERS SUPPRESSES EARLY AFTERDE- POLARIZATION OF SIMULATED CARDIAC ACTION POTENTIALS. Kazuharu Furutani , Kunichika Tsumoto, Jon T. Sack, Yoshihisa Kurachi 2345-Pos Board B361 UNPERCEIVED PROPERTIES OF THE RELATIONSHIP BETWEEN NET MEM- BRANE CURRENT AND ACTION POTENTIAL DURATION. Antonio Zaza 2346-Pos Board B362 SLOW DELAYED RECTIFIER K + CURRENT STABILIZES VENTRICULAR ACTION POTENTIALS ACROSS SPECIES. Meera Varshneya , Ryan A. Devenyi, Eric A. Sobie Voltage-gated K Channels and Mechanisms of Voltage Sensing and Gating III (Boards B363–B391) 2347-Pos Board B363 A UNIVERSAL MOLECULAR MECHANISM FOR C-TYPE INACTIVATION IN POTASSIUM CHANNELS.  Jing Li , Jared Jostmey, Eduardo Perozo, Benoit Roux 2348-Pos Board B364 CONVERTING THE DEPOLARIZATION-ACTIVATED SHAKER K V CHANNEL INTO A HYPERPOLARIZATION-CONDUCTING CATION-SELECTIVE CHANNEL BY TWO PORE MUTATIONS. Evelyn Martinez-Morales, Laura C. Coonen, Dieter V. Van de Sande, Dirk J. Snyders , Alain J. Labro 2349-Pos Board B365 OBSERVATION OF STRUCTURAL CHANGES IN CLOSED K + CHANNELS BY VOLTAGE CLAMP SPECTROSCOPY. Sebastian Fletcher-Taylor, Parashar Thapa, Jon T. Sack, Bruce E. Cohen 2350-Pos Board B366 A CHARACTERISTIC EXTRACELLULAR LOOP OF PRESTIN MODULATES ITS VOLTAGE OPERATING POINT. Makoto F. Kuwabara , Koichiro Wasano, Satoe Takahashi, Justin Bodner, Tomotaka Komori, Sotaro Uemura, Jing Zheng, Tomohiro Shima, Kazuaki Homma 2351-Pos Board B367 QUANTUM CALCULATIONS ON A VOLTAGE SENSING DOMAIN OF K V 1.2: H + TRANSFER AND GATING CURRENT. Alisher M. Kariev, Michael E. Green 2352-Pos Board B368 QUANTUM CALCULATIONS ON AN INTERIOR SEGMENT OF THE K V 1.2 CHANNEL VOLTAGE SENSING DOMAIN. Alisher M. Kariev , Michael E. Green 2353-Pos Board B369 DOES VSP MULTIMERIZE AND DOES IT MATTER? Vamseedhar Rayaprolu , Perrine Royal, Guillaume Sandoz, Susy Kohout 2354-Pos Board B370 DETECTION OF VOLTAGE-SENSING RESIDUES IN MEMBRANE PRO- TEINS. Marina A. Kasimova , Erik Lindahl, Lucie Delemotte 2355-Pos Board B371 KEY RESIDUES IN THE INTERFACE BETWEEN VOLTAGE SENSOR AND PORE DOMAIN IN SHAKER POTASSIUM CHANNELS.  João L. Carvalho-de-Souza , Francisco Bezanilla

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