Biophysical Society 62nd Annual Meeting | Program Guide

2472-Pos Board B488 BIOPHYSICS OF SERCA2A/DWORF COMPLEX AND IMPLICATIONS FOR THERAPEUTIC DESIGN. Ang Li , Daniel R. Stroik, Tory M. Schaaf, Benjamin D. Grant, David D. Thomas 2473-Pos Board B489 STOPPED-FLOW CALCIUM ASSOCIATION KINETICS OF HYPERTROPHIC CARDIOMYOPATHY ASSOCIATED TROPONIN T MUTATIONS. MatthewM. Klass , Sarah J. Lehman, Jil C. Tardiff 2474-Pos Board B490 MEMBRANE DOMAINS AND CAMP COMPARTMENTATION IN CARDIAC MYOCYTES. Shailesh R. Agarwal , Jackson Gratwohl, Mia Cozad, Pei-Chi Yang, Colleen E. Clancy, Robert D. Harvey 2475-Pos Board B491 ABERRANT CARDIAC MUSCLE MECHANICS IN A HYPERTROPHIC CARDIO- MYOPATHY TROPONIN T ILE79ASN TRANSGENIC MOUSE. Karissa M. Dieseldorff Jones , David Gonzalez-Martinez, Maicon Landim-Vieira, Yeojung Koh, Bjorn C. Knollmann, P. Bryant Chase, Hyun S. Hwang, Jose R. Pinto 2476-Pos Board B492 KINETIC IMPLICATIONS FROM A MODEL OF CARDIAC LENGTH-DEPEN- DENT ACTIVATION. William C. Hunter , Timothy Alcid 2477-Pos Board B493 TIME-RESOLVED FRET DETECTION OF THE MYOSIN SUPER-RELAXED OFF STATE IN CARDIAC THICK FILAMENT. Sami Chu , Lien A. Phung, Joseph M. Muretta, David D. Thomas 2478-Pos Board B494 TURNING THE AZIMUTHAL MOTIONS OF ADJACENT TROPOMYOSINS INTO A COUPLED N-BODY PROBLEM IN A BROWNIAN MODEL OF CARDIAC THIN FILAMENT ACTIVATION. Yasser Aboelkassem , Kimberly J. McCabe, Gary Huber, Joakim Sundnes, Andrew D. McCulloch 2479-Pos Board B495 PROTEIN KINASE D MODULATION OF CARDIAC PROTEIN PHOPHA- TASES. Marie R. L. Verberckmoes , Bruno B. Jackobsen, Logan R. J. Bailey, Brent M. Wood, Julie Bossuyt 2480-Pos Board B496 METHYLGLYOXAL MODIFICATIONS ARE ELEVATED IN THE MYOFILAMENT OF DIABETIC CARDIOMYOPATHY PATIENTS AND REDUCE MYOFILAMENT FUNCTION. Maria Papadaki , Ronald J. Holewinski, Nikolai Smolin, Marisa J. Stachowski, Cheavar A. Blair, Kenneth S. Campbell, Seth L. Robia, Jona- than A. Kirk Microtubules, Structure, Dynamics and Associated Proteins (Boards B497–B526) 2481-Pos Board B497 COMPUTATIONAL MODELING OF TUBULIN-TUBULIN LATERAL INTERAC- TION: MOLECULAR DYNAMICS AND BROWNIAN DYNAMICS. Mahya Hemmat , David J. Odde 2483-Pos Board B499 ALL TUBULINS ARE NOT ALIKE: DIMER DISSOCIATION AND MONOMER EXCHANGE DIFFER DEPENDING ON THE BIOLOGICAL SOURCE OF TUBU- LIN. Felipe Montecinos-Franjola, Sumit Chaturvedi, Peter Schuck, Dan L. Sackett 2482-Pos Board B498 BINDING INTERACTIONS WITH TUBULIN’S C-TERMINAL TAIL AS STUDIED BY SOLUTION NMR. Allison M. Whited , Kathryn P. Wall, Scott Tilden, Loren E. Hough 2484-Pos Board B500 NUCLEOTIDE-DEPENDENT CONFORMATIONAL DYNAMICS AND ENERGET- ICS OF TUBULIN. Maxim Igaev , Helmut Grubmüller

2485-Pos Board B501 NACL AFFECTS MICROTUBULE PERSISTENCE LENGTH. Brandon J. Harris , Jennifer L. Ross, Taviare L. Hawkins 2486-Pos Board B502 MICROTUBULE SELF-ORGANIZATION IN THE PRESENCE OF CROWDING AGENTS. Carline A. Fermino do Rosario 2487-Pos Board B503 MICROTUBULE PATTERNS THROUGH GROWTH AND CROSSLINKING.  Bianca Edozie 2488-Pos Board B504 LABEL FREE HIGH SPEED WIDE FIELD IMAGING OF SINGLE MICROTU- BULES USING INTERFERENCE REFLECTION MICROSCOPY. Mohammed Mahamdeh , Steve Simmert, Anna Łuchniak, Erik Schäffer, Jonathon Howard 2489-Pos Board B505 CATASTROPHIC DEPOLYMERIZATION OF MICROTUBULES DRIVEN BY SUB- UNIT SHAPE CHANGE.  Jonathan A. Bollinger , Mark J. Stevens 2490-Pos Board B506 MICROTUBULE DEPOLYMERIZATION INHIBITED BY MACROMOLECULAR CROWDING. Virginia VanDelinder , nathan Bouxsein, Randy Ko, George Bachand, Rishi Jain 2491-Pos Board B507 AGE-DEPENDENT CATASTROPHES AND MACROSCOPIC SWITCHING TRAN- SITION IN DYNAMIC MICROTUBULES. Aparna J S , Ranjith Padinhateeri, Dibyendu Das 2492-Pos Board B508 AFM STUDIES OF THE STRUCTURE AND PHYSICAL PROPERTIES OF MICROTUBULES PRODUCED WITH DRUGS AND GTP ANALOGUES. Karen Richardson, Hsein-Shu Liao, Maryam Raftari, Citlally Garcia, Dan Sackett, Albert J. Jin 2493-Pos Board B509 SKELETAL MUSCLE CONTRACTION ALTERS MICROTUBULE PROPERTIES THAT IMPACT FUNCTION. Camilo Vanegas, Humberto Joca, Jack Vander- meulen, Ramzi Khairallah, W Jonathan Lederer, Joseph Stains, Christopher W. Ward 2494-Pos Board B510 GENERATION OF ELECTRICAL OSCILLATIONS BY DIFFERENT MICROTU- BULE STRUCTURES. Maria del Rocio Cantero , Paula L. Perez, Cecilia Villa Etchegoyen, Noelia Scarinci, Horacio F. Cantiello 2495-Pos Board B511 MICRORHEOLOGY OF MICROTUBULE AQUEOUS SOLUTION. Kazutaka Satou , Daisuke Takeuchi, Syuzi Fujii, Hiroshi Orihara, Kentarou Kayano, Arif Md Rashedul Kabir, Ituki Kunita, Akira Kakugo 2496-Pos Board B512 FORMATION OF SHEAR BAND IN A MICROTUBULE SOLUTION. Kei Hamasaki , Daisuke Takeuchi, Shuji Fujii, Hiroshi Orihara, Katsuhiko Sato, Itsuki Kunita, Kentaro Kayano, Arif Md. Rashedul Kabir, Akira Kakugo 2497-Pos Board B513 NUMA RECRUITS DYNEIN ACTIVITY TO MICROTUBULE MINUS-ENDS AT MITOSIS. Christina L. Hueschen , Samuel J. Kenny, Ke Xu, Sophie Dumont 2498-Pos Board B514 GEOMETRICAL PROPERTIES OF ANTIPARALLEL ARRAYS REGULATE MICRO- TUBULE SLIDING AND STALLING BY PRC1 AND KIF4A. Sithara Wijeratne , Radhika Subramanian 2499-Pos Board B515 KINESIN BINDING EXPANDS AND STABILISES THE GDP-MICROTUBULE LAT- TICE. Daniel Peet, Nigel Burroughs, Robert A. Cross

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