Biophysical Society 62nd Annual Meeting | Program Guide

Intrinsically Disordered Proteins (IDPs) and Aggregates III (Boards B113–B141) 2905-Pos Board B113 INTERACTIONS BETWEEN CALCINEURIN, TAU, AND RCAN1-1: A DISOR- DERED TRIO. Trevor P. Creamer , amanda Wilburn, Daryn Smith 2907-Pos Board B115 A TEMPERATURE-CONTROLLED STOPPED-FLOW DROPLET-BASED MI- CROFLUIDIC REACTOR FOR FAST BIOMOLECULAR KINETICS. Tianjin Yang , Stavros Stavrakis, Paolo Arosio, Andrew deMello 2906-Pos Board B114 Education Travel Awardee MANIPULATION OF TAU OLIGOMERIZATION AND AGGREGATION CHAR- ACTERIZED BY TIME-RESOLVED FRET. Chih Hung Lo , Tory Schaaf, Benjamin Grant, Colin Kin-Wye Lim, David Thomas, Jonathan Sachs 2908-Pos Board B116 PROTEIN CHARGE TRANSFER ABSORPTION SPECTRA: AN INTRINSIC PROBE TO MONITOR STRUCTURAL AND OLIGOMERIC TRANSITIONS IN PROTEINS. Mohd. Ziauddin Ansari, amrendra Kumar, Dileep Ahari, Anurag Priyadarshi, Padmavathi Lolla, Rashna Bhandari, Rajaram Swaminathan 2909-Pos Board B117 PRYING INTO HYDRATION WATER IN amYLOIDOGENIC INTRINSICALLY DISORDERED PROTEINS. Samrat Mukhopadhyay , Shruti Arya, Karishma Bhasne, Priyanka Dogra, Avinash K. Singh, Tuhin Khan, Anindya Datta, Board B118 UTILZING FORSTER RESONANCE ENERGY TRANSFER (FRET) AND PHOTO- CROSSLINKING TO VISUALIZE CONFORMATIONAL CHANGES OF ALPHA- SYNUCLEIN.  John J. Ferrie , Conor M. Haney, Jimin Yoon, Buyan Pan, Elizabeth Rhoades, Abhinav Nath, E. James Petersson 2911-Pos Board B119 HIGH-SPEED AFM TO CHARACTERIZE NANOSCALE DYNAMICS OF CROSS- LINKED ABETA42 OLIGOMERS. Siddhartha Banerjee , Zhiqiang Sun, Eric Y. Hayden, David B. Teplow, Yuri L. Lyubchenko 2912-Pos Board B120 EXAMINING THE NANOSECOND-TO-MILLISECOND DYNAMICS OF SIC1 BY FLUORESCENCE TECHNIQUES.  John Darvy M. Castroverde , Taehyung Chris Lee, Gregory-Neal W. Gomes, Julie D. Forman-Kay, Claudiu C. Gradi- naru 2913-Pos Board B121 IMPROVED STRUCTURAL ESTIMATION OF DISORDERED PROTEINS BY CD SPECTROSCOPY: METHOD DEVELOPMENT AND APPLICATION. András Micsonai, Nikoletta Murvai, Éva Bulyáki, Beáta Szabó, Frank Wien, Young- Ho Lee, Matthieu Réfrégiers, Yuji Goto, Péter Tompa, Kyou-Hoon Han, Ágnes Tantos, József Kardos 2914-Pos Board B122 MEASUREMENTS OF AGGREGATION PROPENSITIES OF amYLOID PEP- TIDES BY REAL TIME MONITORING OF GROWTH OF THE AGGREGATES USING TOTAL INTERNAL REFLECTION FLUORESCENCE (TIRF) MICROSCO- PY. Subhas C. Bera , Shamasree Ghosh, Timir Baran Sil, Kanchan Garai 2915-Pos Board B123 ELECTROSTATIC INTERACTIONS TO GUIDE THE SELF-ASSEMBLY OF HIGHLY ORDERED amYLOID-LIKE NANOSTRUCTURES. Ximena Zottig , Soultan Al- Halifa, Michèle Auger, Steve Bourgault Payel Das 2910-Pos

2916-Pos Board B124 EFFECT OF NEIGHBOURING RESIDUES IN CONFORMATIONAL PLASTICITY OF INTRINSICALLY DISORDERED PROTEINS. Sushmita Basu , Ranjit Prasad Bahadur 2917-Pos Board B125 ANTI-COOPERATIVE NEAREST NEIGHBOR COUPLING DETERMINES THE STATISTICAL COIL STATE OF PEPTIDES AND PROTEINS AT HIGH TEMPERA- TURES. Reinhard Schweitzer-Stenner , Siobhan E. Toal 2918-Pos Board B126 SUPERCHARGING AS A GENERAL STRATEGY FOR MAKING PROTEINS INTO CONFORMATIONAL SWITCHES AND THEIR USE IN BIOSENSING. Peter J. Schnatz , Joseph M. Brisendine, Ronald L. Koder 2919-Pos Board B127 ADVANCES IN QUANTITATIVE ANALYSIS OF INTRACELLULAR PROTEIN PHASE SEPARATION KINETICS AND ITS MODULATION BY CELLULAR INTERACTIONS. Ammon E. Posey , Tejbir Kandola, Rohit V. Pappu, Randal Board B128 CHARGED SIDE CHAIN MUTATIONS OF CAMKII PEPTIDE ALTER BINDING AFFINITY FOR CAM THROUGH CREATION OF NON-LOCAL ALTERNATE BINDING CONTACTS.  Jacob Ezerski , Pengzhi Zhang, Margaret Cheung 2921-Pos Board B129 DESIGNING LIGANDS FOR STRUCTURE-LESS PROTEINS. Anirban Das, Anju Yadav, Barun Kumar Maity, Bappaditya Chandra, Alexander Korn, Juniane Adler, Sri Rama Koti Ainavarapu, Daniel Huster, Sudipta Maiti 2922-Pos Board B130 EXPLORING THE TUNABILITY OF THE AGGREGATION AND GELATION PRO- CESS OF TRIPEPTIDES. David DiGuiseppi , Reinhard Schweitzer-Stenner, Nicolas Alvarez 2923-Pos Board B131 PHASE SEPARATION OF THE VARIABLE DOMAIN OF DYNAMIN RELATED PROTEIN 1 IN TMAO SUGGESTS A ROLE IN ASSEMBLY. Blake Hill , ammon Posey, Mehran Bagheri, Nolan Kennedy, James Harden 2924-Pos Board B132 PREVENTION OF AGGREGATION/FIBRILLATION OF HUMAN SERUM ALBUMIN BY SURFACTANT AND ANTI-INFLAMMATORY DRUG UNDER PHYSIOLOGICAL CONDITIONS: BIOPHYSICAL ASPECTS. Achal Mukhija , Nand Kishore 2925-Pos Board B133 International Travel Awardee DYNAMICS BASED DRUG DESIGN FOR INTRINSICALLY DISORDERED PRO- TEINS. Barun K. Maity 2926-Pos Board B134 SEQUENCE-ENCODED CHARGE PATTERNING OF THE INTRINSICALLY DIS- ORDERED TAIL OF FTSZ IMPACTS POLYMERIZATION AND BACTERIAL CELL DIVISION. Megan Cohan , ammon Posey, Anuradha Mittal, Steven Grigsby, Alex Holehouse, Paul J. Buske, Petra A. Levin, Rohit V. Pappu 2927-Pos Board B135 MULTI-SITE PHOSPHORYLATION MODULATES THE CONFORMATION AND ELECTROSTATIC RESPONSE OF INTRINSICALLY DISORDERED PROTEIN BRUSHES. Ruoxing Lei 2928-Pos Board B136 International Travel Awardee PROTON-INDUCED SWITCHING OF AN INTRINSICALLY DISORDERED DOMAIN OF A MELANOSOMAL PROTEIN INTO A POLYMORPHIC FUNC- TIONAL amYLOID. Priyanka Dogra , Sourav Singha Roy, Mily Bhattacharya, Suchitra S. Prabhu, Samrat Mukhopadhyay Halfmann 2920-Pos

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