Biophysical Society 62nd Annual Meeting | Program Guide

2941-Pos Board B149 CONSERVATION OF FOLDING MECHANISM IN COTRANSLATIONAL FOLD- ING OF TITIN I27. Pengfei Tian , Annette Steward, Jane Clarke, Robert B. Best 2942-Pos Board B150 THE STRUCTURAL BASIS FOR INITIATION FACTOR 2 ACTIVATION DURING TRANSLATION INITIATION. Kelvin Caban, Michael Pavlov, Sandip Kaled- honkar, Ziao Fu, Joachim Frank, Måns Ehrenberg, Ruben L. Gonzalez, Jr. 2943-Pos Board B151 IDENTIFYING THE RNA KINETIC TRAPS IN RIBOSOME ASSEMBLY. Riley C. Gentry , Eda Koculi 2944-Pos Board B152 DYNAMICS OF EF-TU AND ITS EFFECT ON GROWTH IN LIVE ESCHERICHIA COLI . Mainak Mustafi , James C. Weisshaar 2945-Pos Board B153 DYNAMICS OF EUKARYOTIC TRANSLATION INITIATION.  Jinfan Wang , Joseph D. Puglisi 2946-Pos Board B154 THE EVOLUTION OF THE RIBOSOME EXIT TUNNEL AND ITS IMPACT ON TRANSLATION DYNAMICS. Khanh Dao Duc , Sanjit Batra, Yun Song 2947-Pos Board B155 GROWTH PHASE DEPENDENT EFFECTS ON SPATIAL DISTRIBUTION OF E. COLI CHROMOSOMES AND RIBOSOMES. Sonisilpa Mohapatra 2948-Pos Board B156 TRANSLATIONAL CONTROL OF CANCER STEM CELLS. Yasunari Kanda , Naoya Hirata, Shigeru Yamada, Daiju Yamazaki 2949-Pos Board B157 CRYO-EM REVEALS MOLECULAR TRANSFORMERS IN ORGANELLES. Alex- ey amunts 2950-Pos Board B158 NASCENT PROTEINS INTERACT WITH KEY REGIONS OF THE OUTER SUR- FACE OF THE RIBOSOME. AndrewM. Fuchs , Valeria Guzman-Luna, Rayna Addabbo, Silvia Cavagnero 2951-Pos Board B159 SINGLE-MOLECULE ANALYSIS OF RIBOSOME AND FACTOR ASSEMBLY PATHWAYS ON A VIRAL MRNA. Alex G. Johnson , Joseph D. Puglisi 2952-Pos Board B160 STUDYING THE NASCENT PEPTIDE CHAIN IN THE RIBOSOMAL EXIT TUN- NEL. Nadin Haase , Wolf Holtkamp, Reinhard Lipowsky, Marina Rodnina, Sophia Rudorf 2953-Pos Board B161 RIBOSOMAL PROTEIN DYNAMICS ON THE HUMAN RIBOSOME. Christo- pher Lapointe , Joseph Puglisi DNA Structure and Dynamics II (Boards B162–B181) 2954-Pos Board B162 SEQUENCE SELECTIVITY, COOPERATIVITY AND COMPETITION IN THE EQUILIBRIUM BINDING OF PSORALENS TO DNA. Stephen A. Winkle , Sigal Dahan, Doreen Patichi, Cinthya Susanibar Tinoco, Giselle Valdes 2955-Pos Board B163 USING MINICIRCLES TO TEST THE ROLE OF DNA BENDING IN MISMATCH RECOGNITION BY RAD4/XPC. Sagnik Chakraborty , Debamita Paul, Jung- Hyun Min, Phoebe A. Rice, Anjum Ansari

2929-Pos Board B137 CONFORMATIONAL EFFECTS OF VARIOUS HYDROPHOBIC-TO-HYDRO- PHOBIC SUBSTITUTION LOCATED AT THE MIDPOINT OF THE INTRINSI- CALLY DISORDERED REGION OF PROBDNF. Ruchi Lohia , Grace Brannigan 2930-Pos Board B138 Education Travel Awardee INSIGHTS INTO THE BALANCE BETWEEN FOLDING AND AGGREGATION DURING A PROTEIN’S LIFE. Matthew D. Dalphin , Yoo Jin Song, Rayna Addabbo, Yue Liu, Angela Varela, Andrew Stangl, Teddy Jennaro, Silvia Cavagnero 2931-Pos Board B139 GLOBAL DIMENSIONS ARE DECOUPLED FROM ELECTROSTATICS IN THE INTRINSICALLY DISORDERED PROTEIN SIC1. Gregory Gomes , Mickael Krzeminski, Julie Forman-Kay, Claudiu Gradinaru 2932-Pos Board B140 INTRINSICALLY DISORDERED PROTEINS PH-INDUCED STRUCTURAL TRANSITIONS IN OVERCROWDED MILIEU. Alexander V. Fonin , Sitdikova K. Asiya, Iuliia A. Gagarskaia, Elena I. Kostyleva, MaksimM. Karasev, Olga I. Povarova, Vladimir N. Uversky, Irina M. Kuznetsova, Konstantin K. Board B141 HIDDEN STRUCTURAL CODES IN PROTEIN INTRINSIC DISORDER.  Gonzalo de Prat Gay Ribosomes & Translation (Boards B142–B161) 2934-Pos Board B142 ALLOSTERIC LOGIC OF THE V. VULNIFICUS ADENINE RIBOSWITCH RE- SOLVED BY FOUR-DIMENSIONAL CHEMICAL MAPPING. Rhiju Das 2935-Pos Board B143 SIMULTANEOUS FORCE AND FLUORESCENCE MEASUREMENTS ON SINGLE RIBOSOMES DEMONSTRATE THAT MRNA SECONDARY STRUC- TURES DO NOT RESTRICT EF-G CATALYZED TRANSLOCATION. Varsha P. Desai , Filipp Frank, Maurizio Righini, Antony Lee, Ignacio Tinoco, Carlos J. Bustamante 2936-Pos Board B144 HOW 2’- O -METHYLATION IN MRNA DISRUPTS TRNA DECODING DURING TRANSLATION ELONGATION.  Junhong Choi , Gabriele Indrisiunaite, Hasan DeMirci, Ka-Weng Ieong, Jinfan Wang, Alexey Petrov, Arjun Prabhakar, Gideon Rechavi, Dan Dominissini, Chuan He, Måns Ehrenberg, Joseph D. Puglisi 2937-Pos Board B145 FLUORESCENT DYE DYNAMICS ATTACHED TO EF-TU AND THEIR EFFECT ON A HETERO-FRET SYSTEM. Senthilkumar Kailasam , Luc Roberts, Hans- JoachimWieden 2938-Pos Board B146 UNFOLDING INTERMEDIATE OF MRNA PSEUDOKNOT CORRELATES WITH RIBOSOMAL FRAMESHIFTING. Kai-Chun Chang , Po-Szu Hsieh, An-Yi Lee, Emmanuel Salawu, You-Hsin Lin, Yu-Ting Chen, Jin-Der Wen 2939-Pos Board B147 COUPLED RIBOSOME CONFORMATIONAL AND COMPOSITIONAL DYNAM- ICS IN THE MECHANISM OF RELEASE FACTOR 3 DURING TRANSLATION TERMINATION. Arjun Prabhakar , Joseph D. Puglisi 2940-Pos Board B148 HOWMECHANICAL FORCES ON THE RIBOSOME MODULATE THE SPEED OF PROTEIN SYNTHESIS. Benjamin Fritch, Sarah Leininger, Phillip Hudson, Lee Woodcock, Carol Deutsch, Edward P. O’Brien Turoverov 2933-Pos

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