Biophysical Society 62nd Annual Meeting | Program Guide

3104-Pos Board B312 CARDIAC ACTION POTENTIAL PROPAGATION THROUGH COMPACT FIBROBLASTS IN 3D CARDIAC MICROTISSUES ENGINEERED FROM SELF- ASSEMBLED SPHEROIDS AS BUILDING BLOCKS. Tae Yun Kim , Celinda M. Kofron, Michelle King, Alexander R. Markes, Anawon O. Okundaye, Zhilin Qu, Ulrike Mende, Bum-Rak Choi 3105-Pos Board B313 CARDIOMYOCYTE ZO-1 REGULATES INTERCALATED DISC ORGANIZATION AND WHOLE HEART PHYSIOLOGY. Wenli Dai , Le Shen, Rangarajan Na- dadur, Kaitlyn Shen, Margaret Gadek, Michael Broman, Ivan Moskowitz, Christopher Weber 3106-Pos Board B314 A FOUR MICROELECTRODE METHOD TO STUDY INTRACELLULAR ION CONCENTRATION AND TRANSPORT IN SKELETAL MUSCLE FIBERS. Judith A. Heiny, Stephen C. Cannon, Marino Di Franco 3107-Pos Board B315 CARDIAC CA V 1.2 SIGNATURE INDUCED BY MINERALOCORTICOID IN VES- SELS. Débora Falcón Boyano , Thassio R. Mesquita, Rogelio Salazar-Enciso, Hussein Kobeissy, Angelica Rueda, Natalia López-Andrés, Ana Maria Gómez Gómez, Jean-Pierre Benitah 3108-Pos Board B316 HAEMMODULATION OF ARTERIAL SMOOTH MUSCLE CELL LARGE-CON- DUCTANCE CA 2+ -ACTIVATED K + (BK) CHANNEL ACTIVITY. Modupe Ayeni Muscle Regulation (Boards B317–B322) 3109-Pos Board B317 BIOENGINEERING AND CHARACTERIZATION OF TROPONIN PEPTIDES FOR USE AS THERAPEUTIC REAGENTS TO MODULATE MUSCLE CONTRACTIL- ITY. Sienna Wong , Hanzhong Feng, Jian-Ping Jin 3111-Pos Board B319 TROPONIN BRIDGES AND STRETCH ACTIVATION IN INSECT FLIGHT MUSCLE. Demetris Koutalianos, Kate English, Belinda Bullard 3110-Pos Board B318 INFLUENCE OF RESIDUE-77 ON FLEXIBILITY OF AN EXTENSIVE PORTION OF TROPOMYOSIN TPM1.1 (ALPHA). Anthonydura Madhushika M. Silva , David H. Heeley 3112-Pos Board B320 MYOGENIC DIFFERENTIATION OF IPSC HOMOLOGOUS OF A NEMALINE MYOPATHY-CAUSING NONSENSE MUTATION IN TNNT1 GENE. Anupom Mondal , Jian-Ping Jin 3113-Pos Board B321 GM7325 TRANSCRIPTION IS REGULATED BY MYOD IN ACTIVATED MUSCLE SATELLITE CELLS. Daisuke Takei , Miyuki Nishi, So-ichiro Fukada, Masao Doi, Hitoshi Okamura, Akiyoshi Uezumi, Lidan Zhang, Morikatsu Yoshida, Mikiya Miyazato, Atsuhiko Ichimura, Hiroshi Takeshima 3114-Pos Board B322 BOTH ACTIN MYOSIN ATTACHMENT AND DETACHMENT KINETICS AF- FECT ACTIN SLIDING VELOCITIES AND ARE INFLUENCED BY MECHANICAL LOAD. Travis J. Stewart , Sam Dugan, Diego Acala, Richard Brizendine, Christine R. Cremo, Josh E. Baker Intracellular Transport (Boards B323–B334) 3115-Pos Board B323 UPTAKE AND LOCALIZATION OF amINOGLYCOSIDE ANTIBIOTICS IN LIVE ESCHERICHIA COLI. Eliza M. Warszawik , Jochem H. Smit, Yichen Li, Mark Loznik, Avishek Paul, Thorben M. Cordes, Andreas Herrmann

3091-Pos Board B299 DEFINING THE LIMITS OF STEM-CELL DERIVED CARDIOMYOCYTES (SC-CMS) TO DETECT CARDIAC PROARRHYTHMIC LIABILITIES. Carlos A. Obejero-Paz , Leslie Ellison, James Kramer, Andrew Bruening-Wright 3092-Pos Board B300 ACTION POTENTIAL TRIANGULATION AND INSTABILITY IN TNT-I79N HU- MAN IPSC-CMS. Lili Wang , Bjorn C. Knollmann 3093-Pos Board B301 INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES (COR.4U) CHARACTERIZED ON AN AUTOMATED PLANAR PATCH CLAMP SYSTEM (QPATCH HT). Daniel R. P. Sauter , Kazuya Tsurudome, Rasmus Jacobsen, Goeran Mattsson 3094-Pos Board B302 A NEW ANALYSIS PIPELINE TO IMPROVE ASSESSMENT OF CARDIAC LIABILITY IN HIGH THROUGHPUT ELECTROPHYSIOLOGY SCREENS WITH ROUTINE MOA DETECTION FOR SLOW ONSET COMPOUNDS. Stephan Steigele, Ana L. Teixeira, Martin Ginkel, Verity A. Talbot, Lisa J. McWil- liams, Matt Bridgland-Taylor, Leigh Foster , Stephan Heyse 3095-Pos Board B303 CORRELATION OF I KR BLOCK WITH ACTION POTENTIAL CHANGES IN HU- MAN STEM CELL DERIVED CARDIOMYOCYTES. Brian K. Panama , Mark W. Nowak, Sanjot Singh, Randall L. Rasmusson, Glenna C L Bett 3096-Pos Board B304 A FAST OPTICAL ION CHANNEL ASSAY FOR ASSESSING ACTION POTEN- TIALS IN HUMAN INDUCED PLURIPOTENT STEM CELL CARDIOMYO- CYTES. Stephen S. Smith , Thomas Lila, Jay Trautman, Andrew Blatz 3097-Pos Board B305 HIGH-THROUGHPUT STUDY OF RABBIT VENTRICLE ACTION POTENTIAL POPULATIONS IN MI MODEL. Quentin Lachaud , Niall MacQuaide, Francis Burton, Godfrey Smith 3098-Pos Board B306 OXIDATIVE STRESS REMODELING OF ZEBRAFISH CARDIAC ELECTRICAL GRADIENTS. Nicholas A. James, Ashraf R. Beshay, Eileen Chang, Thao P. Nguyen 3099-Pos Board B307 RING FINGER PROTEIN 207 DEGRADES T613M KV11.1 CHANNEL.  Hannah A. Ledford , Seojin Park, Padmini Sirish, Aiyana M. Emigh, Wilson Xu, Valeriy Timofeyev, James R. Priest, Marco V. Perez, Euan A. Ashley, Vladimir Yarov-Yarovoy, Xiao-Dong Zhang, Nipavan Chiamvimonvat 3100-Pos Board B308 TRANSIENT OUTWARD K CURRENT DEFINES CA DYNAMICS ON INTACT MOUSE HEARTS. Micaela Lopez Alarcon, Juan I. Felice, Emilino Medei, Ariel L. Escobar 3101-Pos Board B309 FAST SODIUM CURRENTS IN RAT ATRIAL AND VENTRICULAR MYO- CYTES. Rachel E. Caves, Stephanie CM Choisy, Simon M. Bryant, Jules C. Hancox, Andrew F. James 3102-Pos Board B310 SELECTIVE CHLORIDE ION SENSING MICROELECTRODES USING A BORON CLUSTER IONOPHORE. Rafal M. Dziedzic , Marino DiFranco, Stephen C. Cannon, Alexander M. Spokoyny 3103-Pos Board B311 COMPARISON OF CARDIAC CELL FUNCTION IN CAVEOLIN-3 KNOCK-OUT AND TAC MICE. Cherrie H. Kong , Simon M. Bryant, Hanne C. Gadeberg, Judy J. Watson, David M. Roth, Hemal H. Patel, Andrew F. James, Mark B. Cannell, Clive H. Orchard

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