Biophysical Society 62nd Annual Meeting | Program Guide

Exhibitor Presentations Exhibit Hall Rooms 5 and 6

Room 5: Sunday, February 18

1:30 PM–3:00 PM HORIBA Scientific

New Fluorescence and Absorbance Spectrometer Concept HORIBA Scientific is pleased to announce the launch of their newest spectroscopic instrument; DuettaTM fluorescence and absorbance spectrometer. Duetta combines fluorescence with absorbance in a single compact instrument, making this unique combination a break- through in the field of fluorescence spectroscopy. Duetta is a new analytical fluorometer concept with many unique benefits over traditional bench-top scanning spectrofluorometers. It is a complete Fluorescence and Absorbance Spectrometer from the UV to the NIR (250 to 1,100 nm) using CCD detection to allow for fluo- rescence spectral acquisitions in the blink of an eye. Duetta saves you money and time, and because it can acquire both fluorescence and absorbance simultaneously, it offers enhanced dynamic range and pre- cise multivariate analysis capabilities for molecular fingerprinting. The Duetta fluorescence and absorbance spectrometer is powered by a new software platform from HORIBA called EzSpecTM. EzSpec is an intuitive user interface that allows for simple operation, acquisition and analysis. It features single button Apps for routine fluorescence and absorbance applications. 1. Simultaneous Absorbance-Transmission and EEM Fluorescence Spectrometer (A-TEEMTM) 2. 3-D Excitation Emission Matrix Acquired in 30 seconds 3. Automatic Inner Filter Effect (IFE) Correction for quantitative fluo- rescence measurements over a wide range of concentrations 4. Millisecond CCD detection with effective scan speed of 980,000 nm/minute (with 50 ms integration) 5. UV-Vis-NIR Absorbance Detection range from 250 to 1,100 nm 6. UV-Vis-NIR Fluorescence Detection range from 250 to 1,100 nm 7. Sensitivity Specification of 3,000:1 RMS for water Raman Come see a presentation and demonstration of this exciting new instrument from the leaders in fluorescence! Speaker Cary Davies, Global Product Line Manager, Fluorescence Division, HORIBA Scientific Key benefits that will be presented:

11:30 am–1:00 pm Carl Zeiss Microscopy LLC Zeiss Live Cell Imaging Tools Allow New Levels of Resolu- tion, Sensitivity, and Throughput Imaging live cell samples offers unique insights into cellular function and gives the freedom to explore dynamic changes in cell behavior. Successful live cell imaging relies on maintenance of an appropriate cel- lular environment and an effort to minimize cellular damage. Keeping up with dynamic events inside a living cell requires an optical design that produces gentle high signal to noise images. The optical design and configuration of the imaging platform plays a crucial role in the success of an imaging experiment. ZEISS has introduced a completely automated inverted platform, the Celldiscoverer 7, which simplifies every aspect of experimental setup and gives every live cell experiment the best chance for success. At the heart of the Celldiscoverer 7 is a completely unique optical concept with record setting optical resolution and light throughput. Paired with gentle LED illumination and image detectors designed for low magnifi- cation the Celldiscoverer 7 achieves new levels of imaging throughput. Complicated tasks of microscope configuration and optimization are completely automated and designed to make the most of any sample type. Automated control of cellular environment allows imaging stabil- ity to be maintained over long time course experiments. The system can be expanded with a robotic plate loading system to allow high throughput imaging from plate and slide based samples. The ZEISS LSM 880 confocal with Airyscan and Fast technology offers a unique detector design that counters the typical loss of sample light experienced when using a confocal pinhole. The Airyscan detector provides superresolution down to 120 nm in x, y, and 350 nm in z with higher SNR allowing acquisitions with lower laser illumination. The Fast mode for Airyscan provides the ability to image four times faster while maintaining improved resolution and SNR over conventional confocal imaging. The result is gentle superresolution imaging and the needed speed to follow live cells and quantify fast live cell events. Join this workshop and learn how the ZEISS Celldiscoverer 7 and the LSM 880 Airyscan can help your imaging experiments in completely new ways. Speakers Scott Olenych, North American Product Marketing Group Manager, Light Microscopy, Carl Zeiss Microscopy LLC Renée Dalrymple, Product Marketing Manager, Imaging Products, Carl Zeiss Microscopy LLC

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