Biophysical Society 62nd Annual Meeting | Program Guide

575-Pos Board B345 MECHANOSENSATION THROUGH RADICALS IN TENSED COLLAGEN.  Christopher Zapp , Agnieszka Obarska-Kosinska, Csaba Daday, Reinhard Kappl, Frauke Gräter 576-Pos Board B346 A LEVER-LIKE TRANSDUCTION PATHWAY FOR LONG-DISTANCE CHEMI- CAL- AND MECHANO-GATING OF THE MECHANOSENSITIVE PIEZO1 CHANNEL. Yanfeng Wang , Shaopeng Chi, Qiancheng Zhao, Jianhua Wang, Tingxin Zhang, Jie Geng, Guang Li, Li Wang, Kun Wu, Yu Rao, Liansuo Zu, Wei He, Huifang Guo, Meng-Qiu Dong, Bailong Xiao 577-Pos Board B347 Education Travel Awardee RECOVERY OF EQUILIBRIUM FREE ENERGY FROM NON-EQUILIBRIUM THERMODYNAMICS WITH MECHANOSENSITIVE ION CHANNELS IN E. COLI . Ugur Cetiner , Oren Raz, Sergei Sukharev, Christopher Jarzynski 578-Pos Board B348 DECIPHERING BINDING CAPABILITIES OF HUMAN ANTIBODIES TO DE- FINED PATTERNS OF ANTIGENS. Björn Högberg 579-Pos Board B349 DEVELOPMENT OF A BRET-BASED MOLECULAR TENSION SENSOR TO STUDY ALTERED TENSIONS IN DISEASE PATHOGENESIS. Eric J. Aird , Kas- sidy J. Tompkins, Wendy R. Gordon 580-Pos Board B350 USING A FLUCTUATION ANALYSIS OF LIMIT CYCLE OSCILLATIONS IN INNER EAR HAIR BUNDLES AS A NEW TEST OF LOW DIMENSIONAL DYNAMICAL MODELS.  Janaki K. Sheth 581-Pos Board B351 ACTIVATION OF ENDOGENOUS PIEZO1 CHANNELS BY SHEAR STRESS IN EXCISED MEMBRANE PATCHES.  Jian Shi , Baptiste Rode, David J. Beech 582-Pos Board B352 STRAINED COLLAGEN RESISTS BACTERIAL COLLAGENASE DEGRADA- TION. Karanvir Saini , Manorama Tiwari, Jerome Irianto, Charlotte Pfeifer, Cory Alvey, Dennis E. Discher 583-Pos Board B353 Education Travel Awardee LIPID-GEL MODEL OF BIOLOGICAL MEMBRANES. Zheng Shi , Zachary T. Graber, Tobias Baumgart, Howard A. Stone, Adam E. Cohen 584-Pos Board B354 CELL TYPE SPECIFIC SPLICING OF PIEZO2 REGULATES MECHANOTRANS- DUCTION. Marcin Szczot, Leah Pogorzala, Hans Jürgen Solinski, Mark Hoon, Alexander T. Chesler Intracellular Calcium Channels and Calcium Sparks and Waves I (Boards B355–B374) 585-Pos Board B355 UNDERSTANDING THE MOLECULAR MECHANISM OF CATION PERME- ATION IN THE CARDIAC RYANODINE RECEPTOR (RYR2) CHANNEL USING COMPUTATIONAL ELECTROPHYSIOLOGY. Williams E. Miranda , Van A. Ngo, S.R. Wayne Chen, Sergei Y. Noskov 586-Pos Board B356 FRET-BASED TRILATERATION APPLIED TO THE MAPPING OF CAMWITHIN THE RYANODINE RECEPTOR. Bengt Svensson , Robyn T. Rebbeck, David D. Thomas, Razvan L. Cornea 587-Pos Board B357 GENERATION AND CHARACTERIZATION OF CPVT1 CARDIOMYOCYTES USING HUMAN INDUCED PLURIPOTENT STEM CELLS AND CRISPR/CAS9 GENE EDITING. Naohiro Yamaguchi , Xiao-Hua Zhang, Hua Wei, Martin Morad

559-Pos Board B329 ELECTROPHYSIOLOGICAL CHARACTERIZATION OF MECHANO-ACTIVATED CURRENTS IN HUMAN ENDOTHELIAL CELLS. Luis O. Romero , Julio F. Cordero-Morales, Valeria Vásquez 560-Pos Board B330 CPOW Travel Awardee ROLE OF PIEZO CHANNELS IN UROTHELIAL CELL MECHANOTRANSDUC- TION. Marianela G. Dalghi 561-Pos Board B331 PROBING THE MECHANOSENSING MECHANISM OF GPR56 TO UNDER- STAND ADHESION GPCR-RELATED DISEASE PATHOGENESIS.  Kassidy J. Tompkins 562-Pos Board B332 CYTOSKELETON-ASSOCIATED PROTEINS MODULATE THE TENSION SENSI- TIVITY OF PIEZO1. Charles D. Cox , Navid Bavi, Boris Martinac 563-Pos Board B333 MOLECULAR DYNAMICS STUDY FOR EXPLORING THE FORCE TRANS- MISSION PATHWAY IN THE BACTERIAL MECHANOSENSITIVE CHANNEL MSCL. Yasuyuki Sawada , Takeshi Nomura, Masahiro Sokabe 564-Pos Board B334 A PROTEIN INTERACTION MECHANISM FOR SUPPRESSING THE MECHA- NOSENSITIVE PIEZO CHANNELS. Shaopeng Chi 565-Pos Board B335 FUNCTIONAL INVESTIGATION OF DYSTROGLYCAN’S PROTEOLYSIS DO- MAIN. Amanda Hayward 566-Pos Board B336 FULLY AUTOMATED ULTRASOUND-BASED TOUCH ASSAY FOR SMALL MODEL ORGANISMS. Miriam B. Goodman , Holger Fehlauer 567-Pos Board B337 A COMPUTATIONAL STUDY TOWARDS ENGINEERING AN MSCL NANO- VALVE. Adam D. Martinac , Navid Bavi, Omid Bavi, Boris Martinac 568-Pos Board B338 MECHANICAL TENSION SERVES AS A LATE G1 CELL CYCLE CHECK- POINT. Nash D. Rochman , Nicolas Perez, Jiaxiang Tao, Sean Sun 569-Pos Board B339 LOAD-DEPENDENT INTERACTION OF SINGLE Α- AND Α/Β-CATENIN COM- PLEXES WITH ACTIN. Marios Sergides , Claudia Arbore, Francesco Saverio Pavone, Marco Capitanio 570-Pos Board B340 THE ANREP EFFECT: ROLE OF TITIN STRAIN. Younss Ait-Mou, Jody Martin, Marion Greaser, Mengjie Zhang, Pieter de Tombe 571-Pos Board B341 DISSECTING THE FAST HYPOOSMOTIC PERMEABILITY RESPONSE IN E. COLI . Anthony Schams, Madolyn Britt, Ian Rowe, Ugur Cetiner, Andriy Anishkin, Sergei Sukharev 572-Pos Board B342 ULTRASOUND MODULATES PIEZO1-MEDIATED MECHANOTRANSDUC- TION IN NEURO2A CELLS. Wei-Wen Liu , Pai-Chi Li 573-Pos Board B343 BIOMECHANICS OF HIV AND IMMUNE CELL INTERACTIONS INVESTIGAT- ED USING MAGNETIC TWEEZER FORCE SPECTROSCOPY. James L. Flewellen , Pavel Tolar 574-Pos Board B344 MECHANICAL STRESS MODULATES CYTOSOLIC CA 2+ IN MLO-Y4 OSTEO- CYTE-LIKE CELLS. Sheenah Lynn Bryant , Elizabeth T. Leung, Daniel R. Prather, Conner Patricelli, Daniel Fologea

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