Biophysical Society 62nd Annual Meeting | Program Guide

1229-Pos Board B138 PARTITION COEFFICIENT OF ARGININE BETWEEN TRANSLOCON INTE- RIOR AND LIPID PHASE. Denis G. Knyazev , Mirjam Zimmermann, Roland Kuttner, Peter Pohl 1230-Pos Board B139 HOW CLC CHLORIDE TRANSPORTER FOLDS. Duyoung Min , Robert E. Jefferson, Yifei Qi, Jing Yang Wang, Mark A. Arbing, Wonpil Im, James U. Bowie 1231-Pos Board B140 STRUCTURE AND FUNCTION OF THE TRANSPORTER NKCC1. Corinne Portioli , Marco De Vivo, Ming Zhou, Laura Cancedda 1232-Pos Board B141 IRON MEDIATED INTERACTION OF ALPHA SYNUCLEIN WITH LIPID RAFTS IN MODEL MEMBRANE SYSTEMS. Loredana Casalis , Fabio Perissinotto, Denis Scaini 1233-Pos Board B142 MECHANISM OF ASSEMBLY OF A TRANSMEMBRANE HELIX DIMER FROM ALL-ATOM SIMULATION. Robert B. Best , Jan Domanskiz, Mark S.P. San- som, Phillip Stansfeld 1234-Pos Board B143 MOLECULAR MECHANISM OF POLYPEPTIDE INSERTION INTO BILAYER AND EXIT. Gregory Slaybaugh , Dhammika Weerakkody, Oleg Andreev, Yana Reshetnyak 1235-Pos Board B144 MECHANISMS BY WHICH LIPIDS SHAPE THE REACTION COORDINATE OF GLPG PROTEASE. Ana-Nicoleta Bondar 1236-Pos Board B145 A MINIMAL HELICAL HAIRPIN MOTIF RECAPITULATES MISFOLDING AND PHARMACOLOGICAL RESCUE OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR). Georg Krainer , Antoine Treff, An- dreas Hartmann, Tracy A. Stone, Sandro Keller, Charles M. Deber, Michael Schlierf 1237-Pos Board B146 FUNCTIONAL STABILIZATION OF PURIFIED HUMAN CFTR BY NBD1 MUTA- TIONS AND BY PHOSPHATIDYLSERINE.  Ina Urbatsch , Zhengrong Yang, Ellen Hildebrandt, Fan Jiang, Qingxian Zhou, Jiangli An, Bala M. Xavier, Netaly Khazanov, Hanoch Senderowitz, John C. Kappes, Christie G. Brouil- lette Transcription (Boards B147–B167) 1238-Pos Board B147 ROLES OF UPSTREAM PROMOTER DNA IN BACTERIAL TRANSCRIPTION INITIATION. Munish Chhabra, Christina Mcnerney, Katelyn Callies, Claire Cimperman, Andrew Xue, Irina Shkel, Tom Record 1239-Pos Board B148 ELECTRON MICROSCOPY AND INTEGRATIVE MODELING SHED LIGHT ON THE MECHANISMS OF TRANSCRIPTION INITIATION. Chunli Yan, Yuan He, Eva Nogales, Ivaylo Ivanov 1240-Pos Board B149 TRANSCRIPTION ENHANCEMENT BY NUCLEAR SPECKLE ASSOCIA- TION.  Jiah Kim , Nimish Khanna, Andrew S. Belmont 1241-Pos Board B150 SINGLE-MOLECULE ANALYSIS OF THE INFLUENZA VIRUS REPLICATION INITIATION MECHANISM. Nicole C. Robb , Aartjan J.W. te Velthuis, Ervin Fodor, Achillefs N. Kapanidis

1242-Pos Board B151 HOW DOES A VIRAL RNA POLYMERASE RATCHET ALONG DNA WITHOUT BACKTRACKING? Lin-Tai Da, Chao E, Yao Shuai, Shaogui Wu, Xiao-Dong

Su, Jin Yu 1243-Pos

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Board B152 ABORTIVE AND PRODUCTIVE TRANSCRIPTION INITIATION BY E. COLI RNA POLYMERASE. Kate Henderson , Cristen M. Molzahn, Lindsey C. Felth, Claire Evensen, Sarah Dyke, Guanyu Liao, Jack Prazich, M. Thomas Record 1244-Pos Board B153 THE THERMAL MOBILITY OF NUCLEOSOMES: A VERSATILE TOOL FOR THE REGULATION OF GENE EXPRESSION. Ariel Kaplan 1245-Pos Board B154 TRANSCRIPTION DYNAMICS AT THE HIV-1 REPORTER LOCUS.  Linda Stephanie Forero-Quintero , Michael May, Edouard Bertrand, Euge- nia Basyuk, Hiroshi Kimura, Brian Munsky, Timothy Stasevich 1246-Pos Board B155 REAL-TIME OBSERVATION OF POLYMERASE- PROMOTER CONTACT RE- MODELING DURING TRANSCRIPTION INITIATION. Furqan M. Fazal , Cong A. Meng, Steven M. Block 1247-Pos Board B156 EFFECTS OF TEFM ON MITOCHONDRIAL RNA POLYMERASE TRANSCRIP- TION ELONGATION. Cheng Xue 1248-Pos Board B157 MFD DYNAMICALLY REGULATES TRANSCRIPTION. Tung T. Le , Yi Yang, Chuang Tan, Margaret Suhanovsky, Robert M. Fulbright, Jr., James T. In- man, Ming Li, Jaeyoon Lee, Jeffrey W. Roberts, Alexandra M. Deaconescu, Michelle D. Wang 1249-Pos Board B158 HIGHLY SPECIFIC CIRCULAR RNA QUANTIFICATION IN SINGLE YEAST CELLS. Gable M. Wadsworth , Harold D. Kim 1250-Pos Board B159 IN VIVO EFFECTS OF DISCRIMINATOR SEQUENCES ON TRANSCRIPTION INITIATION IN E. COLI . Kevin Lauterjung , Xiangyang Liu, Kate Henderson, Vatsan Raman, Tom Record 1251-Pos Board B160 USING MINIMAL SYNTHETIC ENHANCERS TO REACH A PREDICTIVE UNDERSTANDING OF TRANSCRIPTIONAL REGULATION IN DEVELOP- MENT. Myron Child, Armando Reimer , Emma Luu, Hernan Garcia 1252-Pos Board B161 MEDIATOR FORMS CLUSTERS WITH RNA POLYMERASE II IN LIVE STEM CELLS. Won-Ki Cho , Jan-Hendrik Spille, Micca Hecht, Choongman Lee, Ibrahim Cisse 1253-Pos Board B162 MICROARRAY ANALYSIS REVEALS DEREGULATED LNCRNAS AND MRNAS IN DB/DB MICE PLASMA AND HEART: DIAGNOSTIC BIOMARKERS OF DIABETIC CARDIOMYOPATHY. Tarun Pant 1254-Pos Board B163 THE ROLE OF THE CBP TRANSCRIPTIONAL ACTIVATOR IN THE CIRCADIAN REPRESSIVE COMPLEX. Efrain H. Ceh Pavia , Jennifer Fribourgh, Leslee Nguyen, Carrie L. Partch 1255-Pos Board B164 TRANSCRIPTIONAL DYNAMICS AND THE REGULATION OF CHROMATIN ACCESSIBILITY IN DROSOPHILA EMBRYONIC DEVELOPMENT. Elizabeth Eck , Jonathan Liu, Hernan Garcia

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