Biophysical Society 62nd Annual Meeting | Program Guide

1509-Pos Board B418 EFFECTS AND ACTIVATION MECHANISMS OF IVERMECTIN ON G-PRO- TEIN-GATED INWARDLY RECTIFYING POTASSIUM CHANNELS.  I-Shan Chen , Michihiro Tateyama, Yuko Fukata, Motonari Uesugi, Yoshihiro Kubo 1510-Pos Board B419 GAUSSIAN-ACCELERATED MOLECULAR DYNAMICS MODELING LEADS TO IDENTIFICATION OF SLAC1 ANION CHANNEL RESIDUES FOR CO 2 SIGNAL- ING IN ARABIDOPSIS GUARD CELL.  Jingbo Zhang , Nuo Wang, Yinglong Miao, Felix Hauser, Wouter-Jan Rappel, J. AndrewMcCammon, Julian Board B420 CHIMERIC KV7.4 CHANNEL WITH amINO-TERMINUS OF KV7.5 HAS PUTA- TIVE PROTEIN KINASE A PHOSPHORYLATION SITE AND IS SUFFICIENT TO CONFER PARTIAL SENSITIVITY TO CYCLIC ADENOSINE MONOPHOSPHATE/ PROTEIN KINASE A (CAMP/PKA) PATHWAY. Lyubov I. Brueggemann , Leanne L. Cribbs, Kenneth L. Byron 1512-Pos Board B421 HUMAN SPERM ROTATION IS REGULATED BY ASYMMETRICALLY POSI- TIONED FLAGELLAR CONTROL UNITS. Nadja Mannowetz , Melissa R. Miller, Samuel J. Kenny, Steven A. Mansell, Michal Wojcik, Robert S. Zucker, Ke Xu, Polina V. Lishko 1513-Pos Board B422 MODULATION OF KCNQ CHANNELS BY INTRACELLULAR ZINC. Haixia Gao, Aurélien Boillat, Dongyang Huang, Ce Liang, Chris Peers, Nikita Gamper 1514-Pos Board B423 ASSIGNING FUNCTION TO THE D AND E HELICES OF HCN CNBD. ANDREA SAPONARO, ALESSANDRO PORRO, CHIARA DONADONI, BINA SANTORO, GERHARD THIEL, Anna Moroni 1515-Pos Board B424 CAVEOLAE-MEDIATED ACTIVATION OF MECHANOSENSITIVE I CL,SWELL CHAN- NELS DISRUPTS CONDUCTION AND PROMOTES ARRHYTHMOGENESIS IN PULMONARY VEINS AND SUPERIOR VENA CAVA. Di Lang , Yuri V. Egorov, Rose Wang, Leonid V. Rosenshtraukh, Alexey V. Glukhov 1516-Pos Board B425 Education Travel Awardee MUSCARINIC RECEPTOR NEUROMODULATION OF KCNQ M-TYPE K+, AND OTHER, CHANNELS IN HIPPOCAMPAL PRINCIPAL NEURONS INVOLVES STRIKING CELL-SPECIFIC REGULATION CONTROLLING EXCITABILITY. Chase M. Carver , Mark S. Shapiro 1517-Pos Board B426 THE UNFOLDED PROTEIN RESPONSE CONTRIBUTES TO ELECTRICAL RE- MODELING IN HUMAN CARDIOMYOCYTES. Man Liu , Guangbin Shi, Anyu Zhou, Samuel C. Dudley, Jr. 1518-Pos Board B427 K 2P 2.1 (TREK-1)-ACTIVATOR COMPLEXES REVEAL A CRYPTIC SELECTIVITY FILTER BINDING SITE. Marco Lolicato , Cristina Arrigoni, Takahiro Mori, Yoko Sekioka, Clifford Bryant, Kimberly A. Clark, Daniel L. Minor 1519-Pos Board B428 Education Travel Awardee STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF BESTROPHIN CHANNEL INACTIVATION. George Vaisey , Stephen B. Long 1520-Pos Board B429 Β3-ADRENERGIC RECEPTOR REGULATION OF CARDIAC ION CHANNELS IN OVERWEIGHT INSULIN RESISTANT RATS. Aysegul Durak, Yusuf Olgar, Erkan Tuncay, Belma Turan 1521-Pos Board B430 MODELING MECHANISMS OF CARDIAC L-TYPE CA 2+ CHANNEL REGU- LATION: INTERACTIONS OF VOLTAGE, CA 2+ , AND ISOFLURANE. Neeraj Manhas , amadou K.S. Camara, Ranjan K. Dash Schroeder 1511-Pos

1497-Pos Board B406 INTERACTION SITES OF SEROTONIN TYPE 3A INTRACELLULAR DOMAIN (5-HT 3A -ICD) WITH CHAPERON PROTEIN RIC-3. Elham Pirayesh , Michaela Jansen 1498-Pos Board B407 MAPPING TWO NEURSTEROID MODULATORY SITES IN GLIC: A PROTO- TYPIC PENTAMERIC LIGAND GATED ION CHANNEL. Wayland WL Cheng , Zi-Wei Chen, Bracamontes R. John, Melissa M. Budelier, Kathiresan Krishnan, Daniel J. Shin, Cunde Wang, Xin Jiang, Douglas F. Covey, Gustav Akk, Alex S. Evers 1499-Pos Board B408 STRUCTURES AND FUNCTIONS OF ELIC-GABAAR CHIMERAS. Qiang Chen , Marta M. Wells, Palaniappa Arjunan, Tommy S. Tillman, Devin Adell, Aina E. Cohen, Yan Xu, Pei Tang 1500-Pos Board B409 Education Travel Awardee PROBING CONFORMATIONAL MOTIONS UNDERLYING ANESTHETIC DRUG ACTIONS IN A LIGAND-GATED ION CHANNEL. Sritejasvinthi Karimikonda , Varun Tiwari, Candice S. Klug, Cynthia Czajkowski 1501-Pos Board B410 EXPANSION OF A TRANSMEMBRANE CAVITY FACILITATES ANESTHETIC POTENTIATION OF A PENTAMERIC LIGAND GATED ION CHANNEL. Marie Lycksell , Stephanie A. Heusser, Rebecca J. Howard, Erik Lindahl 1502-Pos Board B411 THE PROS OF NACH AND 5-HT3 RECEPTORS. Sarah C. Lummis , Richard Mosesso, Dennis A. Dougherty 1503-Pos Board B412 Education Travel Awardee ALLOSTERIC MODULATION OF THE PENTAMERIC LIGAND-GATED ION CHANNEL ELIC BY BARBITURATES. Hannelore De Peuter , Marijke Brams, Delphine Joseph, Daniel Bertrand, Chris Ulens 1504-Pos Board B413 HIGHLY PURE SOLUBLE CHIMERAS OF THE INTRACELLULAR DOMAIN OF ANIONIC PENTAMERIC LIGAND-GATED ION CHANNELS. Akash Pandhare , Ali F. Ahmed, Jackson V. Littlejohn, Michaela Jansen 1505-Pos Board B414 HIGH PRECISION IN FLUIDIC CONTROL PROVIDES NEEDED AND RELIABLE ACCURACY IN LIGAND INDUCED CURRENT RESPONSES OF ACETYLCHO- LINE AND GABA RECEPTORS. Ali Yehia , Haiyang Wei Ion Channel Regulatory Mechanisms II (Boards B415–B438) 1506-Pos Board B415 PKC ACTIVATION INDUCES UBIQUITINATION-DEPENDENT KV1.3 ENDO- CYTOSIS MEDIATED BY NEDD4-2 UBIQUITIN LIGASE. Ramón Martínez- Mármol, Katarzyna Styrczewska, Mireia Pérez-Verdaguer, Albert Vallejo- Gracia, Núria Comes, Alexander Sorkin, Antonio Felipe 1507-Pos Board B416 REVEALING MOLECULAR COUPLING BETWEEN ANION SELECTIVITY AND STRUCTURAL TRANSITIONS IN VOLTAGE-DEPENDENT ANION CHANNEL (VDAC). Van Ngo , Tatiana K. Rostovtseva, Sergey M. Bezrukov, Sergei Y. Noskov 1508-Pos Board B417 TEMPERATURE CONDITIONING INCREASES CA 2+ SENSITIVITY AND ACTIVA- TION KINETICS OF ANO6 VARIANTS.  Joo Hyun Nam , Yung Kyu Kim, Sung Joon Kim

M O N D A Y

95