Biophysical Society 63rd Annual Meeting | Program Guide

Protein Structure and Conformation IV (Boards B1 - B35) 2329-Pos Board B1 NEURONAL CALCIUM SENSOR DREAM INTERACTIONS WITH INSULINO- TROPIC AGENT REPAGLINIDE. Maria D. Santiago , Maria Daniel Santiago, Jaroslava Miksovska 2330-Pos Board B2 THE EFFECTS OF COMMON DISEASE-CAUSING VARIATIONS ON THE STRUCTURE AND STABILITY OF TREM2: AN IN SILICO EXAMINA- TION. Hunter B. Dean , Erik D. Roberson, Yuhua Song 2331-Pos Board B3 MUTATION OF RESIDUES IN CD LOOP AND DISTAL POCKET IMPACT PRO- TEIN STABILITY OF HUMAN NEUROGLOBIN. Ruipeng Lei , David Butcher, Sophie Bernad, Valerie Derrien, Jaroslava Miksovska 2332-Pos Board B4 UNDERSTANDING PROTEIN HD EXCHANGE DATA USING MOLECULAR DYNAMICS SIMULATIONS. Dipak B. Sanap , V. V. Hemanth Giri Rao, Juan R. Perilla, Shachi Gosavi 2333-Pos Board B5 THE MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR ASSOCI- ATES WITH MULTIPLE DOMAINS OF CBP/P300, INCLUDING THE E1A BINDING FACE OF TAZ2. Kathleen Vergunst, Alexandra Brown, Makenzie Branch, David N. Langelaan 2334-Pos Board B6 EVOLUTION OF STABILITY/FLEXIBILITY RELATIONSHIPS IN BETA-LAC- TAMASE.  John Patterson , Matthew C. B. Tsilimigras, Dennis R. Livesay, Donald J. Jacobs 2335-Pos Board B7 DYNAMICS OF THE PROTEIN INTERFACES OF THE EBOLA VIRUS VP40 STRUCTURAL MATRIX FILAMENT. Elumalai Pavadai , Nisha Bhattarai, Prem P. Chapagain, Bernard S. Gerstman 2336-Pos Board B8 TRAVEL AWARDEE LINKING THE SEQUENCE, ANTI-TUMOR FUNCTION, AND SHARED STRUC- TURAL FEATURES OF CLASS IB HYDROPHOBINS. Calem Kenward , David N. Board B9 MEASURING IONIC STRENGTH CHANGES USING FLUORESCENCE LIFETIME AND TIME-RESOLVED ANISOTROPY. Robert Miller, Cody Aplin, Anh Cong, Christin Libal, Rowan Simonet, Emma Kauffman, Margaret Gurumani, Ryan Leighton, Alexander Naughton, Jessica Marshik, Arnold J. Boersma, Ahmed A. Heikal, Erin D. Sheets 2338-Pos Board B10 ADVANCES IN THE STRUCTURAL AND BIOCHEMICAL DETERMINATION OF SEVERAL DYNAMIN-LIKE GTPASES. Andrew D. Kehr , Shuxia Meng, Mat- thew F. Martin, David Chan, Jenny E. Hinshaw 2339-Pos Board B11 EVOLUTION OF TRANSIENT HELICITY AND DISORDER IN LATE EMBRYO- GENESIS ABUNDANT PROTEIN COR15A. Oluwakemi Sowemimo , Wade Borcherds, Patrick Knox-Brown, Tobias Rindfleisch, Anja Thalhammer, Gary Daughdrill 2340-Pos Board B12 TRAVEL AWARDEE MOLECULAR DYNAMICS STUDIES OF DYNAMIN OLIGOMERS IN SOLU- TION. Dalia Hassan , Frank X. Vazquez Langelaan 2337-Pos

2341-Pos Board B13 THE DEVELOPMENT OF INTRINSICALLY FLUORESCENT UNNATURAL AMINO ACIDS FOR IN VIVO INCORPORATION INTO PROTEINS. Chloe M. Jones , Itthipol Sungwienwong, E. James Petersson 2342-Pos Board B14 APPLYING HYDROGEN EXCHANGE MASS SPECTROMETRY COUPLED WITH NUMERICAL SIMULATIONS TO INVESTIGATE TOXIC MISFOLDING OF ß2- MICROGLOBULIN. Angelika Hirsch , John Strahan, Amy Wagaman, Sheila Jaswal 2343-Pos Board B15 STUDYING MUTATIONS IN GEOBACILLUS KAUSTOPHILUS TILS TO PROBE CHANGES IN STRUCTURE AND MOBILITY USING MOLECULAR DYNAMIC (MD) SIMULATIONS. Ferdiemar C. Guinto , Rebecca W. Alexander 2344-Pos Board B16 TRAVEL AWARDEE DIFFERENTIATING STRUCTURAL CHANGES OF GLYCOPROTEINS IN SOLU- TION USING SMALL ANGLE SCATTERING ANALYSIS. Taylor N. Segally , Luis A. Palacio, Jason Kim, Christopher B. Stanley, Soenke Seifert, Horia I. Board B17 STRUCTURAL INVESTIGATIONS INTO THE SERUM ENDONUCLEASE DNASE1L3, AS IT RELATES TO SYSTEMIC LUPUS ERYTHEMATOUS.  Jon J. McCord , Faraz Harsini, Peter Keyel, Roger B. Sutton 2346-Pos Board B18 INTERACTION OF THE CURLI ACCESSORY PROTEINS CSGE AND CSGF WITH THE HUMAN ISLET AMYLOID POLYPEPTIDE. Osmar Meza-Barajas, Isamar Aranda, Ashwag Binmahfooz, Sajith A. Jayasinghe 2347-Pos Board B19 COMPARATIVE INVESTIGATION OF NATIVE-STATE DYNAMICS IN TRYPSIN FUNCTIONAL VARIANTS BY HYDROGEN EXCHANGE MASS SPECTROM- ETRY. Kimberly Burnett , Maxum Paul, Katie Ventre, Abel Samanez, Sheila Jaswal 2348-Pos Board B20 TRAVEL AWARDEE STRUCTURE AND FUNCTION OF HUMAN VITRONECTIN, A KEY MEDIATOR OF HOST-PATHOGEN INTERACTIONS. Kyungsoo Shin , L. Miya Fujimoto, Luz M. Meneghini, Chandan Singh, Yong Yao, Ye Tian, Francesca M. Marassi 2349-Pos Board B21 SINGLE MOLECULE IMAGING OF DNA STRUCTURE: CLIC MICROSCOPY POWERS MECHANISTIC INSIGHTS FOR DRUG DEVELOPMENT. Francis Stabile , Cynthia Shaheen, Shane Scott, Daniel Berard, David Levens, Craig Benham, Sabrina Leslie 2350-Pos Board B22 TEMPERATURE DEPENDENCE OF THE PROTEIN-CHROMOPHORE HY- DROGEN BOND DYNAMICS IN THE FAR-RED FLUORESCENT PROTEINS MNEPTUNE1, MNEPTUNE2.5 AND MCARDINAL2. Chandra Dhakal , Prem Chapagain, Xuewen Wang 2351-Pos Board B23 INVESTIGATING RECOMBINANT ACINIFORM SILK NANOPARTICLES AS POTENTIAL DRUG CARRIERS AND AS INTERMEDIATES IN SILK FIBRILLO- GENESIS. Stefan A. Warkentin , Jan K. Rainey 2352-Pos Board B24 77SE-NMR PROBES THE PROTEIN ENVIRONMENT OF SELENOMETHIO- NINE. Shiping Xu , Maggie Chen, Mike Boeri, Sharon Rozovsky 2353-Pos Board B25 INVESTIGATE THE EXISTENCE OF DOMAIN SWAPPED DIMER IN ILPB FAM- ILY. Nona Ehyaei , Zahra Assar-Nossoni, James H. Geiger, Babak Borhan Petrache 2345-Pos

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