Biophysical Society 63rd Annual Meeting | Program Guide

Intrinsically Disordered Proteins (IDP) and Aggregates III (Boards B103 - B133) 2431-Pos Board B103 UNDERSTANDING THE KINETIC ROLES OF 14-3-3ZETADURING TAU FILA- MENT FORMATION.  Junwen Xiong , Meng Gao, Yongqi Huang 2432-Pos Board B104 MEMBRANE INTERACTIONS OF IAPP. Mikkel H. Christensen , Birgit Schiøtt 2433-Pos Board B105 INHIBITION OF Α-SYNUCLEIN AMYLOID FIBRIL ELONGATION BY BLOCKING FIBRIL ENDS. Volodymyr V. Shvadchak , Kseniia Afitska, Anna Fucikova, Dmytro A. Yushchenko 2434-Pos Board B106 COMPARING EARLY STAGES OF AMYLOID-BETA AGGREGATION IN DIFFER- ENT MEMBRANOUS ENVIRONMENTS. Abhilash Sahoo , Hongcheng Xu, Silvina Matysiak 2435-Pos Board B107 UNDERSTANDING AND PREVENTING AGGREGATION IN ALPHA-SYNUCLE- IN. Lisa J. Lapidus 2436-Pos Board B108 TRAVEL AWARDEE TERMINAL CAPPING OF AMYLOIDOGENIC TAU FRAGMENTS MODULATES THEIR FIBRILLATION PROPENSITY. Shruti Arya , Pritam Ganguly, Sarah L. Claud, Andrea Arsiccio, Kristi Lazar Cantrell, Joan Emma Shea, Michael T. Bowers 2437-Pos Board B109 OBSERVATION OF STRUCTURAL GROWTH OF FIBRILS OF AMYLIN PRO- TEIN. Suparna Khatun , Shikha Kumari, Agneyo Ganguly, Nisha Pawar, Amar Nath Gupta 2438-Pos Board B110 TRAVEL AWARDEE STRUCTURAL OPTIMIZATION OF Α-SYNUCLEIN FIBRIL GROWTH INHIBI- TORS. Kseniia Afitska , Volodymyr V. Shvadchak, Dmytro A. Yushchenko 2439-Pos Board B111 OLIGOMER CROSS-PROPAGATION BETWEEN WILD-TYPE AND MUTANT AMYLOID-Β IMPLICATE CONFORMATIONAL STRAINS IN AD PHENO- TYPES. Morgan Malone , Dexter N. Dean, Vijay Rangachari 2440-Pos Board B112 SUMOYLATION OF THE NT17 DOMAIN OF HUNTINGTIN INFLUENCES AG- GREGATION AND BINDING TO LIPID MEMBRANES. Faezeh Sedighi , Justin A. Legleiter 2441-Pos Board B113 THE PRESENCE OF MITOCHONDRIA INFLUENCES HUNTINGTIN AGGREGA- TION. Adewale Adegbuyiro , Justin A. Legleiter 2442-Pos Board B114 POST TRANSLATIONAL MODIFICATION OF AΒ INFLUENCES AGGREGATION IN THE PRESENCE AND ABSENCE OF LIPIDS. Albert W. Pilkington , Justin A. Legleiter 2443-Pos Board B115 IMPACT OF N-TERMINAL ACETYLATION ON ALPHA-SYNUCLEIN AMYLOID FORMATION. Matthew D. Watson , Jennifer C. Lee 2444-Pos Board B116 INVESTIGATION OF THE VARIOUS STRUCTURES OF ALPHA-SYNUCLEIN AND THEIR INTERACTIONS WITH SMALL MOLECULES.  John Ferrie , Sam G. Giannakoulias, E. James Petersson

2445-Pos Board B117 INVESTIGATING C99 IN AMYLOID FORMATION USING MOLECULAR DY- NAMICS: FROM SIMPLE TO COMPLEX NEURONAL MODELS.  Jenny Pin-Chia Hsu , Birgit Schiøtt 2446-Pos Board B118 INTERPLAY BETWEEN TWO ISOFORMS OF THE FUNCTIONAL AMYLOID PMEL17 REPEAT DOMAIN. Dexter N. Dean , Jennifer C. Lee 2447-Pos Board B119 TRAVEL AWARDEE STRUCTURAL EVALUATION OF AROMATIC RESIDUES IN Α-SYN AND THEIR ROLE IN GLYCAN BINDING AND CELLULAR UPTAKE.  Jonathan M. Musila , Elizabeth Rhoades 2448-Pos Board B120 Β-SYNUCLEIN AMELIORATES Α-SYNUCLEIN TOXICITY BY MODULATING FIBRIL SHEDDING AND SEEDING PROCESSES. Xue Yang , Jonathan K. Wil- liams, Jean Baum 2449-Pos Board B121 ALPHA-SYNUCLEIN MODULATES STIMULATED EXOCYTOSIS AND BINDS TO MITOCHONDRIA. Meraj Ramezani , Marcus Wilkes, Tapojyoti Das, David Holowka, David Eliezer, Barbara Baird 2450-Pos Board B122 ALPHA-SYNUCLEIN DISRUPTS INTER-MEMBRANE INTERACTIONS. Peter J. Chung , Qingteng Zhang, Hyeondo Luke Hwang, Alessandra Leong, Eric Dufresne, Suresh Narayan, Erin J. Adams, Ka Yee C. Lee 2451-Pos Board B123 ALPHA SYNUCLEIN INCREASES MEMBRANE BINDING WITH RISING LAT- ERAL TENSION.  Jaclyn Ann Robustelli , Zheng Shi, Tobias Baumgart 2452-Pos Board B124 THE EFFECT OF AMYLOID PRECURSOR PROTEIN DIMERIZATION ON ITS CONFORMATION AND CLEAVAGE.  Jacob B. Usadi , Karl Freed, Esmael Haddadian 2453-Pos Board B125 Α-SYNUCLEIN BINDS EXTRACELLULAR COMPLEX N-LINKED GLYCANS.  Melissa Birol , Slawomir P. Wojcik, Andrew D. Miranker, Elizabeth Rhoades 2454-Pos Board B126 TARGETING SOLUBLE AMYLOID OLIGOMERS IN ALZHEIMER’S DISEASE THROUGH DISORDERED PRION PEPTIDES. Zachary A. Levine 2455-Pos Board B127 TRAVEL AWARDEE TAU AMYLOID AGGREGATES: THE CHOICE OF PATHWAYS MAKES THE DIF- FERENCE. Yann Fichou , Songi Han 2456-Pos Board B128 TRAVEL AWARDEE MULTISCALE INVESTIGATION OF MONOMERIC ALPHA-SYNUCLEIN STRUC- TURE AND AGGREGATION. Daisy Alvarado , Frank X. Vazquez 2457-Pos Board B129 BIOPHYSICAL INSIGHTS INTO HOW LIPID MEMBRANES MODULATE HUN- TINGTIN AGGREGATION ASSOCIATED WITH HUNTINGTON’S DISEASE.  Justin Legleiter 2458-Pos Board B130 INVESTIGATING THE EFFECTS OF MODEL SURFACES ON SYNTHETIC PRION PEPTIDE AGGREGATION. Elizabeth A. Yates , Catherine M. Yip 2459-Pos Board B131 METAL-PROMOTED ALPHA-SYNUCLEIN MODIFICATIONS STEER THE AGGREGATE CONFORMATION. Heather R. Lucas , Dinendra L. Abeyaward- hane, Ricardo D. Fernández, Denver R. Heitger, Ashley K. Forney, Cody J. Murgas, Alyson Curry

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