Biophysical Society 63rd Annual Meeting | Program Guide

2405-Pos Board B77 THE PLACEMENT OF VIBRATIONAL PROBE LABELED SUBSTRATES TO THE PHOSPHOPANTETHEINE ARM OF THE E.COLI ACYL CARRIER PROTEIN FOR SITE SPECIFIC VIBRATIONAL SPECTROSCOPY.  Joie Ling , Eliana V. von Krusenstiern, Bashkim Kokona, Louise Charkoudian, Casey H. Londergan 2406-Pos Board B78 HIGH-SPEED ATOMIC FORCE MICROSCOPY SHOWS CONFORMATIONAL DYNAMICS OF CA 2+ /CALMODULIN-DEPENDENT PROTEIN KINASE II.  Mikihiro Shibata , Hideji Murakoshi 2407-Pos Board B79 PROCESSIVE CHITINASE IS BURNT-BRIDGE BROWNIAN MOTOR OPERATED BY FAST CATALYSIS AFTER PEELING RAIL FROM CRYSTALLINE CHITIN. Aki- hiko Nakamura, Kei-ichi Okazaki, Tadaomi Furuta, Minoru Sakurai, Ryota Iino 2408-Pos Board B80 OBSERVING HISTONE H2A.Z EXCHANGE AT THE SINGLE-MOLECULE LEVEL. Matthew F. Poyton , Ashlee Feng, Anand Ranjan, Qin Lei, Sheng Liu, Carl Wu, Taekjip Ha 2409-Pos Board B81 BASIS OF SPECIFICITY IN ETS-1 DNA BINDING DOMAIN TO VARIABLE DNA SEQUENCES. Kenneth Huang , Suela Xhani, Amanda V. Albrecht, Gregory M. K. Poon 2410-Pos Board B82 ANOMALOUS NON-GAUSSIAN VISCOELASTIC AND AGE-DEPENDENT DYNAMICS OF HISTONE-LIKE H-NS PROTEINS IN LIVE ESCHERICHIA COLI. Asmaa Sadoon, Yong Wang 2411-Pos Board B83 INVESTIGATION OF CONFORMATIONAL DYNAMICS INVOLVED IN GE- NOME EDITING EVENTS BY CRISPR-CPF1. Chun Chan , Xiaolin Cheng 2412-Pos Board B84 TRAVEL AWARDEE DETERMINING THE INTERNAL ALLOSTERIC ARCHITECTURE OF DHFR WITH TOTAL SATURATION MUTAGENESIS.  James W. McCormick , Samuel Thompson, Kimberly A. Reynolds 2413-Pos Board B85 UTILIZING EMPIRICAL DATA AND STRUCTURAL DYNAMICS PREDICTION TO OPTIMIZE RATIONAL DESIGN OF THERAPEUTIC PHOSPHOLAMBAN MUTATIONS TO TUNE SERCA FUNCTION. Kim N. Ha , Hannah M. Johnson, Ariana Schneiderhan, Daniel Weber, Joseph Roith, Gianluigi Veglia 2414-Pos Board B86 SUBSTRATE DRIVEN ALLOSTERY IN A MITOCHONDRIAL CYTOCHROME P450 ENZYME. Amit Kumar , D. Estrada Fernando 2415-Pos Board B87 TRAVEL AWARDEE SALT BRIDGES IN UBIQUITIN DETERMINE THE PROTEIN CONFORMA- TIONAL FLEXIBILITY. Shrabasti Bhattacharya , Nidhi Acharya, Sri Rama Koti Ainavarapu 2416-Pos Board B88 Α-CATENIN STRUCTURE AND NANOSCALE DYNAMICS IN SOLUTION AND IN COMPLEX WITH F-ACTIN. Iain Nicholl, David Callaway, Zimei Bu 2417-Pos Board B89 DEUTERATION AND INHIBITOR BINDING DEPENDENCE OF PROTEIN COL- LECTIVE VIBRATIONS. Yanting Deng , Jeffrey Mckinney, Andrea Markelz 2418-Pos Board B90 DYNAMIC AND STRUCTURAL ALLOSTERIC EVENTS BETWEEN THE D/E LINKER AND N-DOMAIN OF CARDIAC TROPONIN C REVEAL A NOVEL MECHANISM FOR CARDIAC MUSCLE REGULATION. Mayra A. Marques , Guilherme A. P. de Oliveira, Adolfo H. Moraes, Maicom Landim-Vieira, Karissa D. Jones, Elio A. Cino, P. Bryant Chase, Jerson L. Silva, José R. Pinto

2419-Pos Board B91 DYNAMICAL COMPARISON BETWEEN MYOGLOBIN AND HEMOGLOBIN REVEALS THE EFFECT OF THE QUATERNARY STRUCTURE OF HEMOGLO- BIN ON ITS SUBUNITS’ DYNAMICS. Rotem Aharoni, Dror Tobi 2420-Pos Board B92 MICRO-SECOND X-RAY SINGLE MOLECULE DYNAMICS OF ALLOSTERIC TWISTING MOTIONS IN HEMOGLOBIN. Yuji C. Sasaki , Masahiro Kuramo- chi, Yuu Okamura, Hiroshi Sekiguchi, Naoki Yamamoto, Naoya Shibayama 2421-Pos Board B93 DIFFRACTED X-RAY BLINKING FROM NANOCRYSTAL ON PROTEIN USED AS INTERNAL MOTION PROBE. Hiroshi Sekiguchi , Masahiro Kuramochi, Yuji C. Sasaki 2422-Pos Board B94 THE EFFECT OF CRYSTAL CONTACT FORCES ON THE PROTEIN GLOBAL MOTIONS.  Jeffrey A. McKinney , Yanting Deng, Deepu George, Andrea Markelz 2423-Pos Board B95 A LIGAND-BINDING SITE IN THE GLUA3 AMPA RECEPTOR N-TERMINAL DOMAIN OBSERVED IN DRUGGABILITY SIMULATIONS AND X-RAY CRYS- TALLOGRAPHY.  Ji Young Lee , James Krieger, Beatriz Herguedas, Javier García-Nafría, Anindita Dutta, Saher A. Shaikh, Ingo H. Greger, Ivet Bahar 2424-Pos Board B96 TRAVEL AWARDEE MOLECULAR ANALYSIS OF DENGUE NS3 HELICASE FUNCTION. Kelly E. Du Pont , Russell B. Davidson, Brian J. Geiss, Martin McCullagh 2425-Pos Board B97 INVESTIGATING THE ROLE OF THE AUXILIARY NUCLEOTIDE BINDING SITES IN THE RECBCD DNA HELICASE. Sivasubramanyan Mangapuram Venkata , Rani Zananiri, Vera Gaydar, Oded Kleifeld, Ariel Kaplan, Arnon Henn 2426-Pos Board B98 ALLOSTERY & DYNAMICS IN NUCLEAR HORMONE RECEPTOR TRANSACTI- VATION. David Lohry , Taylor Stevens, Mark Remec Pavlin, Balananda DK Putcha, Tongye Shen, Elias J. Fernandez 2427-Pos Board B99 BINDING-COUPLED-FOLDING OF INTRINSICALLY DISORDERED PROTEIN EXHIBITS A HIERARCHICAL ENERGY LANDSCAPE. Xiakun Chu , Jin Wang 2428-Pos Board B100 LONG-RANGE INTERACTIONS MEDIATED BY THE DISORDERED NFΚB TRANSCRIPTION ACTIVATION DOMAIN. Dominic Narang , Wei Chen, Allen Po, Elizabeth A. Komives 2429-Pos Board B101 CONTROL OF CELLULAR NETWORKS BY STRUCTURAL DISORDER. Nikolay V. Dokholyan , Onur Dagliyan, Klaus M. Hahn 2430-Pos Board B102 STRUCTURE AND DYNAMICS OF INTRINSICALLY DISORDERED AND UN- FOLDED PROTEINS: INVESTIGATIONS USING SMALL-ANGLE SCATTERING AND NEUTRON SPIN-ECHO SPECTROSCOPY. Felix Ameseder, Laura R. Stin- gaciu, Aurel Radulescu, Olaf Holderer, Peter Falus, Michael Monkenbusch, Ralf Biehl, Dieter Richter, Andreas M. Stadler

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