Biophysical Society 63rd Annual Meeting | Program Guide

2565-Pos Board B237 CHARACTERIZATION OF ALPHA-HELIX DISTORTIONS AT A MEMBRANE SURFACE AND A PARTIAL 3(10)-HELIX BY SOLID-STATE NMR. Matthew J. McKay , Denise V. Greathouse, Roger E. Koeppe 2566-Pos Board B238 LIPID OPTIMIZATION TO IMPROVE THE SOLID-STATE NMR SPECTRA FROM MEMBRANE-SPANNING HELICES WITH GLUTAMIC ACID. Kelsey A. Marr , Matthew J. McKay, Denise V. Greathouse, Roger E. Koeppe 2567-Pos Board B239 TRAVEL AWARDEE LIPID MEMBRANE INFLUENCES INTERACTION BETWEEN THE C1 DOMAIN OF MUNC13-1 AND THE ACTIVATOR. Youngki You , Binhan Yu, Tatyana Igumenova, Joydip Das 2568-Pos Board B240 PROTEIN-LIPID INTERACTIONS REGULATE ATG3 ACTIVITY IN AUTOPHA- GY. Erin R. Tyndall , Yansheng Ye, Zhenyuan Tang, Hong-Gang Wang, Fang Tian 2569-Pos Board B241 STICHOLYSINS, SPHINGOMYELIN AND CHOLESTEROL: A CLOSER LOOK INTO A TRIPARTITE INTERACTION.  Juan Palacios Ortega , Sara García- Linares, Esperanza Rivera-de-Torre, Jose G. Gavilanes, Álvaro Martínez- del-Pozo, J Peter Slotte 2570-Pos Board B242 A 2A ADENOSINE RECEPTOR ACTIVATION STUDIED BY ALL-ATOM SIMULA- TION. Long Chen , Edward R. Lyman 2571-Pos Board B243 MEMBRANE BINDING BY SYNAPTOTAGMIN-LIKE PROTEIN 4: SITE DI- RECTED MUTAGENESIS OF THE LIPID INTERACTION SURFACE. Aml A.A Alnaas , Julianna Oviedo, Abena Siriboe, Sherleen Tran, Mikias Negussie, Hai Lin, Jefferson Knight 2572-Pos Board B244 LIPID-LIPID AND LIPID-PROTEIN INTERACTIONS OF THE MATRIX DOMAIN OF HIV-GAG AT THE VIRAL ASSEMBLY SITE. Viviana Monje-Galvan , Gregory A. Voth 2573-Pos Board B245 A CARTOGRAPHIC VIEW OF MEMBRANE TARGETING AND ASSOCIATION OF THE C2 DOMAIN FROM PROTEIN KINASE C. Muyun Lihan , Emad Tajkhorshid 2574-Pos Board B246 ANNEXIN V IS A SENSOR OF NEGATIVE PLASMA MEMBRANE CURVA- TURE. Christoffer Dam Florentsen , Guillermo S. Moreno Pescador, Alexander K. Sonne, Jesper Nylandsted, Poul Martin Bendix 2575-Pos Board B247 SUBSTRATE INDUCEDCONFORMATIONAL CHANGES OF LIPOSOME- BOUND CYTOCHROME C. Raghed Kurbaj , Bridget Milorey, Reinhard Schweitzer-Stenner 2576-Pos Board B248 MEMBRANE-BOUND STRUCTURES AND ASSOCIATED ELECTRON TRANS- PORT FUNCTIONS OF CYTOCHROME C. Minh D. Phan , Keel Yong Lee, Hanyu Wang, James F. Browning, Sushil K. Satija, John F. Ankner 2577-Pos Board B249 PS MEMBRANE ASYMMETRY INFLUENCES THE FOLDING AND INSERTION OF A TRANSMEMBRANE HELIX. Haden L. Scott , Frederick A. Heberle, John Katsaras, Francisco N. Barrera 2578-Pos Board B250 CAPTURING DYNAMIC TRANSPORTER-LIPID INTERACTIONS. Argyris Politis

2579-Pos Board B251 STRUCTURAL BASIS FOR THE LIPID-MEDIATED INTERACTION OF TUBULIN WITH VDAC REVEALED BY NEUTRON REFLECTOMETRY. David P. Hoogerheide , Sergei Y. Noskov, Philip A. Gurnev, Tatiana K. Rostovtseva, Sergey M. Bezrukov Excitation-Contraction Coupling II (Boards B252 - B266) 2580-Pos Board B252 IDENTIFICATION OF NOVEL RYR1 INHIBITORS BY HIGH-THROUGHPUT SCREENING USING ER CA 2+ MEASUREMENT. Hiroyuki Matsukawa , Ta- kashi Murayama, Takuya Kobayashi, Nagomi Kurebayashi, Mari Ishigami- Yuasa, Shuichi Mori, Hiroyuki Kagechika, Takashi Sakurai 2581-Pos Board B253 DETERMINATION OF HEAT PRODUCTION IN HUMAN SKELETAL MUSCLE FROMMEASUREMENTS OF BASAL CA 2+ MOVEMENTS. Christopher J. Barclay, Bradley S. Launikonis 2582-Pos Board B254 ENHANCEMENT OF SARCOLEMMAL CALCIUM INFLUX IN A NOVEL MOUSE MODEL OF MALIGNANT HYPERTHERMIA. Vikas Kaura , José R López, Marie-Anne Shaw, Paul D. Allen, Philip M. Hopkins 2583-Pos Board B255 MUTATION ANALYSIS OF THE CALCIUM BINDING SITE OF SKELETAL MUSCLE RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL. Venkat R. Chirasani, Le Xu, Jordan S. Carter, Hannah G. Addis, Daniel A. Pasek, Nikolay V. Dokholyan, Gerhard Meissner, Naohiro Yamaguchi 2584-Pos Board B256 MOLECULAR DYNAMICS SIMULATION OF RYANODINE RECEPTOR IN THE PRESENCE AND ABSENCE OF CA 2+ BINDING. Han Wen , Wenjun Zheng 2585-Pos Board B257 EFFECTS OF NOVEL RYR2 INHIBITORS ON DISEASED HEARTS. Nagomi Kurebayashi , Takashi Murayama, Mai Tamura, Shuichi Mori, Mari Yuasa- Ishigami, Hiroyuki Kagechika, Junji Suzuki, Kazunori Kanemaru, Masamit- su Iino, Sachio Morimoto, Takashi Sakurai 2586-Pos Board B258 TRAVEL AWARDEE COOPERATIVE GATING AMONG ION-CHANNEL SPECIES IN JUNCTIONAL SARCOPLASMIC RETICULUM. Elisa Venturi , Fiona O’Brien, David Eber- hardt, Katja Witschas, Sam El-Ajouz, Tsunaki Iida, Miyuki Takeshima, Hiroshi Takeshima, Rebecca Sitsapesan 2587-Pos Board B259 STRUCTURE DEVELOPMENT OF OXOLINIC ACID, A NOVEL INHIBITOR OF TYPE 1 RYANODINE RECEPTOR (RYR1) CA 2+ RELEASE CHANNEL. Yoshiaki Nishijima , Takashi Murayama, Shuichi Mori, Hiroto Iinuma, Noriaki Manaka, Nagomi Kurebayashi, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Takashi Sakurai 2588-Pos Board B260 INVESTIGATION OF MUTANT RYANODINE RECEPTOR CHANNEL ACTIVITY USING FUNCTIONAL ANALYSIS AND MOLECULAR DYNAMICS. Toshiko Yamazawa , Haruo Ogawa, Maki Yamaguchi, Takashi Murayama, Hideto Oyamada, Junji Suzuki, Nagomi Kurebayashi, Kazunori Kanemaru, Takashi Sakurai, Iino Masamitsu 2589-Pos Board B261 CHARACTERIZATION OF AN ANIMAL MODEL FOR CONGENITAL MYOPA- THIES LINKED TO RECESSIVE RYR1 MUTATIONS. Moran Elbaz, Alexis Ruiz, Jan Eckhardt, Susan Treves, Francesco Zorzato

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