Biophysical Society 63rd Annual Meeting | Program Guide

2603-Pos Board B275 DETECTING EARLY RISK OF TYPE 2 DIABETES DURING AN ORAL GLUCOSE TOLERANCE TEST.  Joon Ha , Arthur Sherman 2604-Pos Board B276 TRAVEL AWARDEE EXTRACELLULAR ZINC CONTRIBUTES TO THE SLOW POLYSPERMY BLOCK. Katherine L. Wozniak , Wesley A. Phelps, Miler T. Lee, Anne E. Carlson 2605-Pos Board B277 THE MOLECULAR MECHANISM AND STRUCTURAL ANALYSIS OF MEM- BRANE INTERACTION VIA FERA AND C2 DOMAINS IN FERLINS ASSOCI- ATED WITH MUSCULAR DYSTROPHY AND CANCER. Faraz M. Harsini , Anthony A. Bui, Michael Latham, Anne M. Rice, Mark A. White, Mazdak Bradberry, Edwin R. Chapman, Sukanya Lakshmi, Andrei Turtoi, Isaac L. Scott, Matthew Dominguez, Elahe Masoumzadeh, Jon J. McCord, Jacob Gendelman, Roger Bryan Sutton ,10 2606-Pos Board B278 CALCIUM DEPENDENCE, KINETICS, AND PORE DYNAMICS OF PHYSI- OLOGICAL VESICLE FUSION WITH PLANAR SUPPORTED BILAYERS. Alex J.B. Kreutzberger , Volker Kiesling, Binyong Liang, Patrick Seelheim, Arun Anantharam, J. David Castle, Lukas K. Tamm 2607-Pos Board B279 SYNAPTOTAGMIN-7 ENDOWS A SUBPOPULATION OF CHROMAFFIN GRANULES WITH DISTINCT CALCIUM SENSING AND FUSION PROPER- TIES. Mounir Bendahmane , Alina Chapman-Morales, Noah A. Schenk, Zhang Shuang, Paul M. Jenkins, David R. Giovannucci, Arun Anantharam 2608-Pos Board B280 TRAVEL AWARDEE PIP2 DRIVES CALCIUM-INDEPENDENT ACTIVATION OF TANDEM C2- DOMAIN CALCIUM SENSORS. Mazdak M. Bradberry , Huan Bao, Xiaochu Lou, Edwin R. Chapman 2609-Pos Board B281 FUSION PORE DILATION BY SYNAPTOTAGMIN-1. Zhenyong Wu, Nadiv Dharan, Sathish Thiyagarajan, Ben O’Shaughnessy, Erdem Karatekin 2610-Pos Board B282 DOMAIN STABILITY AND FUNCTIONAL ANALYSIS AT THE AD3 LOCUS OF SYNAPTOTAGMIN 1 C2 DOMAINS. Anthony A. Bui , Faraz M. Harsini, Anne M. Rice, Souvic Karmakar, Kerry Fuson, R. Bryan Sutton 2611-Pos Board B283 HOW CA 2+ AND SYNAPTOTAGMIN TRIGGER SNARE-MEDIATED MEM- BRANE FUSION. Volker Kiessling , Alex J.B. Kreutzberger, Binyong Liang, Sarah B. Nyenhuis, Patrick Seelheim, J. David Castle, David S. Cafiso, Lukas K. Tamm 2612-Pos Board B284 STRUCTURAL CHARACTERIZATION OF FULL-LENGTH SYNAPTOTAGMIN-1 TO CIS OR TRANS MEMBRANES. Sarah B. Nyenhuis , David S. Cafiso 2613-Pos Board B285 SYNAPTIC VESICLE FUSION AND DOCKING DURING THE FIRST 14 MIL- LISECONDS AFTER AN ACTION POTENTIAL. Grant F. Kusick , Shigeki Board B286 SYNAPSIN: A NOVEL INSIGHT FOR PKA PHOSPHO-DOMAINS IN INHIBIT- ING RELEASE PROBABILITY. Agustin Gonzalez-Ruiz, Jose Guzman-Gutier- rez, Pedro Feliciano-Ramos, Ramon A. Jorquera 2615-Pos Board B287 SEQUENTIAL LINK OF KISS-AND-RUN MECHANISM AND CLASSICAL EXO- CYTOSIS AT HIPPOCAMPAL SYNAPSES. Andreas W. Henkel 2616-Pos Board B288 CALCIUM CHANNELS GATE CALCIUM-INDEPENDENT BUT VOLTAGE-DE- PENDENT SECRETION IN MAMMALIAN CELLS. Zhuan Zhou , Rong Huang, Yuan Wang, Jie Li, Xiaohan Jiang, Yinglin Li, Feipeng Zhu, Changhe Wang, Zuying Chai Watanabe 2614-Pos

2590-Pos Board B262 ROLE OF DYSFERLIN’S C2A DOMAIN IN VOLTAGE-INDUCED CALCIUM RE- LEASE AFTER OSMOTIC SHOCK IN MURINE SKELETAL MYOFIBERS. Valeriy I. Lukyanenko , Joaquin Muriel, Robert J. Bloch 2591-Pos Board B263 MEASUREMENTS OF TRIADIC CALCIUM IN DIFFERENTIATED MUSCLE FIBERS USING A GCAMP PROBE TARGETED TO THE JUNCTIONAL SR MEMBRANE. Colline Sanchez , Christine Berthier, Bruno Allard, Vincent Jacquemond 2592-Pos Board B264 MATHEMATICAL MODEL TO SIMULATE SR CALCIUM RELEASE IN MAM- MALIAN SKELETAL MUSCLE WITH IMPAIRED T-TUBULAR STRUCTURE. Vin- cent Jacquemond, Peter Szentesi, Candice Kutchukian, Beatrix Dienes, Laszlo Csernoch 2593-Pos Board B265 POST-DEVELOPMENTAL KNOCKOUT OF ORAI1-MEDIATED STORE-OP- ERATED CALCIUM ENTRY IMPROVES MUSCLE PATHOLOGY IN A MOUSE MODEL OF MUSCULAR DYSTROPHY. Maricela García-Castañeda , Antonio Michelucci, Robert T. Dirksen 2594-Pos Board B266 MULTIPLE SITES OF INTERACTION MAY BE INVOLVED IN THE REGULATION OF CA V 1.1 BY STAC3. Alexander Polster , Philip M. Hopkins, Kurt G. Beam Exocytosis and Endocytosis II (Boards B267 - B294) 2595-Pos Board B267 TO PINPOINT THE LOCATION AND THE ORIENTATION OF PROTEINS ASSO- CIATED WITH DENSE-CORE VESICLES (DCVS) USING CLEM. Bijeta Prasai , Gideon Haber, Kem A. Sochacki, John A. Ciemniecki, Justin W. Taraska 2596-Pos Board B268 RELATION BETWEEN RELEASE OF CATECHOLAMINES AND FFN511 STUDIED WITH ELECTROCHEMICAL DETECTOR ARRAYS. Shailendra Singh Rathore , Meng Huang, Manfred Lindau 2597-Pos Board B269 NS510, A HIGH AFFINITY FLUORESCENT CATECHOLAMINE SENSOR FOR MONITORING NOREPINEPHRINE EXOCYTOSIS. Xin A. Liu , Le Zhang, Timo- thy Glass, Kevin D. Gillis 2598-Pos Board B270 CONDITIONAL KNOCKOUT OF THE SEROTONIN TRANSPORTER (SERT) DEMONSTRATES ITS ROLE IN ACCUMULATING AND MAINTAINING 5-HT HOMEOSTASIS IN THE SYMPATHOADRENAL SYSTEM. Rebecca L. Brindley , Mary Beth Bauer, L. Anne Walker, Meagan A. Quinlan, Ana MD Carneiro, Ji-Ying Sze, Randy D. Blakely, Kevin PM Currie 2599-Pos Board B271 THE SEROTONIN TRANSPORTER MODULATES THE QUANTAL SIZE OF VESICULAR RELEASE EVENTS IN ADRENAL CHROMAFFIN CELLS. Rebecca L. Brindley, Kevin P. Currie 2600-Pos Board B272 HIGH THROUGHPUT DRUG TESTING OF TRANSMITTER RELEASE EVENTS IN CHROMAFFIN CELLS WITH SURFACE MODIFIED CMOS IC. Meng Huang , Shailendra Rathore, Manfred Lindau 2601-Pos Board B273 CHROMOGRANIN A, THE MAJOR LUMENAL PROTEIN IN CHROMAFFIN GRANULES, CONTROLS FUSION PORE EXPANSION. Prabhodh S. Abbineni , Mary A. Bittner, Daniel Axelrod, Ronald W. Holz 2602-Pos Board B274 ALPHA TO BETA CELLS: A PATHWAY TOWARDS A DIABETES CURE. Michael R. DiGruccio , Dave W. Piston

W E

D N

E S

D A Y

148