Biophysical Society 63rd Annual Meeting | Program Guide

Computational Neuroscience (Boards B439 - B442)

2753-Pos Board B425 DUAL-SUBSTRATE ACCESSING MECHANISM OF AN MFS TRANSPORTER FOR LYSOPHOSPHOLIPID FLIPPING ACROSS THE CELL MEMBRANE. Lei Zheng , Yibin Lin, R. N. V. Krishna Deepak, Hao Fan 2754-Pos Board B426 UPTAKE DYNAMICS IN THE LACTOSE PERMEASE (LACY) MEMBRANE PRO- TEIN TRANSPORTER. Dari Kimanius, Erik R. Lindahl, Magnus Andersson 2755-Pos Board B427 TRAVEL AWARDEE DIRECT PROTEIN-LIPID INTERACTIONS SHAPE THE CONFORMATIONAL LANDSCAPE OF SECONDARY TRANSPORTERS. Chloe Martens , Mrinal Shek- har, Antoni Borysik, Andy Lau, Eamonn Reading, Emad Tajkhorshid, Paula Booth, Argyris Politis 2756-Pos Board B428 EXPLORING DYNAMIC TRANSITIONS IN AN ARGININE TRANSPORTER. Zhiyi Wu , Simon Newstead, Philip C. Biggin 2757-Pos Board B429 TRANSPORT ACTIVITY AND NOVEL INHIBITORS OF HUMAN GLUT9 CHAR- ACTERIZED BY MOLECULAR MODELING AND ELECTROPHYSIOLOGY. Jin- ping Zhang, Yanyu Chen, Ting Wu, Qunsheng Lan, Ze-an Zhao, Ying Cao, Pingzheng Zhou, Jianxin Pang 2758-Pos Board B430 MODULATION OF ORIENTATIONAL DYNAMICS OF EXCITATORY AMINO ACID TRANSPORTER-1 BY CHOLESTEROL. Shashank Pant , Emad Tajkhor- shid 2759-Pos Board B431 MECHANISM AND POTENTIAL SITES OF POTASSIUM INTERACTION WITH THE GLUTAMATE TRANSPORTER EAAC1.  Jiali Wang , Christof T. Grewer 2760-Pos Board B432 VOLTAGE DEPENDENT INHIBITOR BINDING TO PLASMA-MEMBRANE GLUTAMATE TRANSPORTERS. Laura J. Zielewicz , Jiali Wang, Elias Ndaru, Christof T. Grewer 2761-Pos Board B433 EVOLUTION OF ION SPECIFICITY IN GLUTAMATE TRANSPORTERS.  Krishna Reddy , Olga Boudker 2762-Pos Board B434 TRAVEL AWARDEE MILLISECOND TIME RESOLUTION BY HS-AFM LINE SCANNING OF FAST GLTPH DYNAMICS. Tina R. Matin , George R. Heath, Gerard Huysmans, Olga Boudker, Simon Scheuring 2763-Pos Board B435 MECHANISTIC CHARACTERIZATION OF THE ALLOSTERIC COMMUNICA- TIONS BETWEEN THE CENTRAL BINDING SITE AND THE EXTRACELLULAR VESTIBULE OF THE SEROTONIN TRANSPORTER. Ara M. Abramyan , Per Plenge, Pia Weikop, Ulrik Gether, Benny Bang-Andersen, Lei Shi, Claus J. Løland 2764-Pos Board B436 IBOGAINE BINDS HUMAN SEROTONIN TRANSPORTER IN MULTIPLE FUNC- TIONAL STATES. Zhiyu Zhao , Po-Chao Wen, Jonathan Coleman, Dongxue Yang, Eric Gouaux, Emad Tajkhorshid 2765-Pos Board B437 BRIDGING THE GAP BETWEEN FUNCTIONAL AND STRUCTURAL DATA. Ver- ena Burtscher , Matej Hotka, Thomas Stockner, Jan-Philipp Machtens, Walter Sandtner 2766-Pos Board B438 IDENTIFYING STRUCTURAL DETERMINANTS OF HIGH-POTENCY MDPV BINDING AT THE HUMAN DOPAMINE TRANSPORTER S1 BINDING SITE. Ty- ler WE Steele , Brian Ruiz, Zachary Spires, Jose M. Eltit

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2767-Pos TRAVEL AWARDEE THE MISSED ROLE OF CYTOSKELETAL FILAMENTS IN INFORMATION PROCESSING. Christian C. Hunley 2768-Pos Board B440 GENERATING A 4D ATLAS OF NUCLEAR POSITIONS IN EMBRYONIC CAE- NORHABDITIS ELEGANS . Ryan Christensen, Alexandra Bokinsky, Anthony Santella, Mark Moyle, Min Guo, Andrew Lauziere, Evan Ardiel, Harshad D. Vishwasrao, Brandon Harvey, Michael Levin , Nensi Karaj, William Mohler, Daniel Daniel Colón-Ramos, Zhirong Bao, Hari Shroff 2769-Pos Board B441 ANALYSIS OF PHOSPHOINOSITIDE-DEPENDENCE OF ACTION POTEN- TIAL FIRING IN SYMPATHETIC NEURONS BY ELECTROPHYSIOLOGICAL RECORDINGS AND MATHEMATICAL MODELING. Martin Kruse , Rayne Whitten 2770-Pos Board B442 EFFECT OF COLUMNAR NEURAL GROUPING ON NETWORK SYNCHRONI- ZATION.  Joseph S. Tumulty , Luis Cruz Computational Methods and Bioinformatics II (Boards B443 - B467) 2771-Pos Board B443 QM/MM STUDY ON CLEAVAGE MECHANISM CATALYZED BY ZIKA VIRUS NS2B/NS3 SERINE PROTEASE. Bodee Nutho , Adrian Mulholland, Than- yada Rungrotmongkol 2772-Pos Board B444 NETWORK-BASED MODELING OF AMYLOID FIBRIL FORMA- TION. Gianmarc Grazioli , Yue Yu, Megha H. Unhelkar, Rachel W. Martin, Carter T. Butts 2773-Pos Board B445 IN SILICO ANALYSIS OF AMINO ACID SUBSTITUTIONS RESULTING FROM SNPS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE. Constance Jeffery , Chang Chen 2774-Pos Board B446 COMPUTATIONAL ANALYSIS OF SPECTROSCOPICAL PROPERTIES AND BINDING AFFINITIES OF OXYLUCIFERIN ANALOGS IN FIREFLY LUCIFERASE PROTEIN. Vardhan Satalkar , Xiaoliang Pan, Enrico Bennasi, Yihan Shao 2775-Pos Board B447 IN SILICO EXPERIMENTS AS A METHOD TO COMPARE TRANSPORTES MECHANISM. Yuly E. Sánchez , Julian Aguilar 2776-Pos Board B448 COMPARATIVE STUDY OF FLAGELLAR AND CYTOPLASMIC DYNEI- NS. Nayere Tajielyato , Joshua Alper, Emil Alexov 2777-Pos Board B449 COMPUTATIONAL DESIGN OF DRUGLIKE ALLOSTERIC INHIBITORS OF AXL AND MET RECEPTOR TYROSINE KINASES. D. S. Dalafave , K. Sureshkumar 2778-Pos Board B450 PREDICTION OF NOVEL HOST-PATHOGEN INTERACTIONS FOR HELICO- BACTER PYLORI THROUGH INTERFACE MIMICRY AND THEIR IMPLICA- TIONS TO GASTRIC CANCER. Emine Guven Maiorov , Chung-Jung Tsai, Buyong Ma, Ruth Nussinov 2779-Pos Board B451 COMPUTATIONAL MODELLING OF TRIADIN’S CONTRIBUTION TO SUDDEN CARDIAC DEATH IN CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA-5 (CPVT-5). Laura Coonfield , Aman Ullah, W. Jonathan Lederer, M. Saleet Jafri Board B439

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