Biophysical Society 63rd Annual Meeting | Program Guide

2780-Pos Board B452 INTEGRATED COMPUTATIONAL MODEL OF LUNG TISSUE BIOENERGET- ICS. Xiao Zhang , Ranjan K. Dash, Anne Clough, Dexuan Xie, Elizabeth Jacobs, Said Audi 2781-Pos Board B453 CANCER-ML: MODELING FITNESS OF UNREGULATED RAS MUTANTS US- ING COMPUTATIONAL MUTAGENESIS AND MACHINE LEARNING. Majid Masso , Arnav Bansal, Akhil Gajjala, Preethi Prem, Iosif I. Vaisman 2782-Pos Board B454 ANOMALOUS HEAT DISSIPATION OF A BROWNIAN MOTOR. Karina Mazzitello , Yi Jiang, Miguel Arizmendi, Jose Iguain, Fereydoon Family 2783-Pos Board B455 THE EFFECT OF THE CELLULAR ENVIRONMENT AND CONFORMATIONAL DYNAMICS ON OPTIMAL ELECTROSTATIC INTERACTIONS WITHIN THE BARSTAR-BARNASE COMPLEX: A COMPUTATIONAL APPROACH. Alyssa J. Kranc , Mala L. Radhakrishnan 2784-Pos Board B456 TRAVEL AWARDEE ROLES OF NUCLEAR CONFINEMENT, EXCLUDED VOLUME, AND PER- SISTENCE ON TAD FORMATIONS, CHROMOSOME TERRITORIES, AND CHROMATIN-NUCLEAR ENVELOPE INTERACTIONS. Samira Mali , Alan Perez-Rathke, Qiu Sun, Gamze Gursoy, Jie Liang 2785-Pos Board B457 NEWMETHOD TO DETERMINE THE EFFECT OF DIMERIZATION ON PRO- TEIN FLEXIBILITY FROMMOLECULAR DYNAMICS SIMULATION USING STRUCTURAL HIERARCHY. Arghya Chakravorty , Jonathan Higham, Emil Alexov, Richard H. Henchman 2786-Pos Board B458 COMPUTATIONAL PREDICTIONS OF DRUG-PROTEIN BINDING KINETICS WITH A HYBRID MOLECULAR DYNAMICS, BROWNIAN DYNAMICS, AND MILESTONING APPROACH. Benjamin R. Jagger , Christopher T. Lee, J. AndrewMcCammon, Rommie E. Amaro 2787-Pos Board B459 TOWARD REDUCING HERG AFFINITIES FOR DAT INHIBITORS WITH A COMBINED MACHINE LEARNING AND MOLECULAR MODELING AP- PROACH. Andrew D. Fant , Soren Wacker, Joslyn Jung, Jiqing Guo, Ara M. Abramyan, Henry J. Duff, Amy H. Newman, Sergei Y. Noskov, Lei Shi 2788-Pos Board B460 GLYCAN STRUCTURE MODELING AND SIMULATION. Wonpil Im 2789-Pos Board B461 PHYSICAL BINDING OF THE TOBACCO SMOKE CARCINOGEN NNK DIA- ZONIUM ION TO THE HUMAN TUMOR SUPPRESSOR GENE TP53 EXON 5. Christos Deligkaris 2790-Pos Board B462 TRANSIENT ANOMALOUS SUBDIFFUSION OF DNA-BINDING SPECIES IN THE NUCLEUS: THE FINAL MODEL. Michael J. Saxton 2791-Pos Board B463 DYNAMICAL NETWORK ANALYSIS OF PROTEIN:RNA COMPLEXES MADE EASY. Marcelo Cardoso dos Reis Melo , Rafael C. Bernardi, Zaida Luthey- Schulten 2792-Pos Board B464 MEGADOCK-WEB: AN INTEGRATED DATABASE OF HIGH-THROUGHPUT STRUCTURE-BASED PROTEIN-PROTEIN INTERACTION PREDICTIONS.  Masahito Ohue , Takanori Hayashi, Yuri Matsuzaki, Keisuke Yanagisawa, Yutaka Akiyama 2793-Pos Board B465 TMB-IBIOMES: A DATABASE OF ALL ATOM SIMULATION AND ANALYSIS FOR NUCLEOSOMES. Ran Sun , Zilong Li, Thomas Connor Bishop

2794-Pos Board B466 IMPLEMENTATION OF THE FDA CIPA QNET MODEL FOR DRUG SAFETY SCREENING WHICH INCREASES EFFICIENCY 25 FOLD. Leigh Korbel, Glenna Bett, Randall Rasmusson 2795-Pos Board B467 TCPRO: AN IN-SILICO RISK ASSESSMENT TOOL FOR BIOTHERAPEUTIC PROTEIN IMMUNOGENICITY. Osman N. Yogurtcu , Zuben E. Sauna, Joseph R. McGill, Million A. Tegenge, Hong Yang Optical Spectroscopy: CD, UV-VIS, Vibrational, Fluorescence (Boards B468 - B494) 2796-Pos Board B468 A REVISED COARSE-GRAINED MODEL OF CIRCULAR DICHROISM OF PRO- TEINS. Mauricio D. Carbajal-Tinoco , Carmen Giovana Granados-Ramírez 2797-Pos Board B469 SPECTRAL ASSIGNMENT OF LYSOZYME COLLECTIVE VIBRATIONS.  Yanting Deng , Jeffrey Mckinney, Tod Romo, Alan Grossfield, Andrea Markelz 2798-Pos Board B470 THE EFFECTS OF CARBAMAZEPINE, AN ANTI-EPILEPTIC DRUG, ON STRUC- TURE AND SURFACE ROUGHNESS OF HEALTHY RAT BONE TISSUES: AN FTIR MICROSPECTROSCOPY AND AFMMICROSCOPY STUDY. Sebnem Garip , Feride Severcan 2799-Pos Board B471 ENVIRONMENT-DEPENDENT PHOTOPHYSICS OF AN ASYMMETRICAL CYA- NINE. Nikita Kumari , Marcia Levitus 2800-Pos Board B472 NOVEL FLUORESCENCE TOOL FOR MEASURING PROTEIN BINDING KINETICS AND ENERGY TRANSFER OVER FULL FLUORESCENCE SPECTRAL RANGES. Karen E. Steege Gall , Alex Siemiarczuk 2801-Pos Board B473 TRAVEL AWARDEE TWIN-FRET: A NEWMOLECULAR RULER FOR BIOMOLECULES. Sankar Jana , Marta Diez-Castellnou, Euan R. Kay, Carlos Penedo 2802-Pos Board B474 EVALUATION OF CELL CULTURE MEDIA USING ABSORPTION AND TRANS- MISSION FLUORESCENCE EXCITATION EMISSION MATRIX (A-TEEM) SPECTROSCOPY. Marinella Sandros , Boqian Yang, Karoly Csatorday, Adam Gilmore, Alvin Togonon, John Bobiak 2803-Pos Board B475 TRAVEL AWARDEE CHARACTERIZATION OF LIPIDS IN LEISHMANIA INFECTED CELLS BY SERS MICROSCOPY. Vesna Zivanovic , Geo Semini, Michael Laue, Daniela Dre- scher, Toni Aebischer, Janina Kneipp 2804-Pos Board B476 THE FLUORESCENCE LIFETIME OF BOUND NADH: CLUES FROM THE PHA- SOR PLOTS. Suman Ranjit , Leonel S. Malacrida, Enrico Gratton 2805-Pos Board B477 INVESTIGATION OF THE STRUCTURAL EFFECTS OF RADIOTHERAPY DOSE RATE ON RAT LUNG TISSUE: AN FTIR IMAGING STUDY.  Ipek Ozyurt , Seb- nem Garip, Fatma Kucuk Baloglu, Faruk Zorlu, Feride Severcan 2806-Pos Board B478 THE DISRUPTION OF BETA SHEETS IN AMYLOIDOGENIC SEQUENCES BY GLY-GLY-ALA. Sarah A. Petty , Andrew T. Mullin, Sam A. Michelhaugh, Benjamin R. Fitzgerald

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