Biophysical Society 63rd Annual Meeting | Program Guide

196-Plat 4:30 pm BAYESIAN NONPARAMETRICS FOR FLUORESCENCE METHODS.  Meysam Tavakoli , Sina Jazani, Ioannis Sgouralis, Steve Presse 197-Plat 4:45 pm DNA BASE DAMAGE AND CONSEQUENTIAL POINT MUTATION CON- TROLS TELOMERE CONFORMATION AND ELABORATES TELOMERASE EXTENSION ACTIVITY.  Hui-Ting Lee , Tapas Paul, Joshua Choe, Samantha Sanford, Patricia L. Opresko, Sua Myong 198-Plat 5:00 pm G-QUADRUPLEX-HELICASE INTERACTIONS AND THE IMPACT OF SMALL MOLECULES.  Parastoo Maleki , Hamza Balci 199-Plat 5:15 pm CHROMATIN REMODELING INDUCED BY THE INVASION OF YEAST PIO- NEER TRANSCRIPTION FACTOR RAP1 REVEALED BY SINGLE-MOLECULE FRET.  Anne-Marinette Cao , Maxime Mivelaz, Iuliia Boichenko, Louise Bryan, Slawomir Kubik, David Shore, Beat Fierz 200-Plat 5:30 pm SINGLE MOLECULE MEASUREMENTS REVEAL CONFORMATIONAL TRAN- SITIONS DURING DNA CLAMP LOADING AND UNLOADING.  SeungWon Lee , Eunjin Ryu, Sukhyun Kang, Hajin Kim 201-Plat 5:45 pm CONFORMATIONAL DYNAMICS RELATED TO MEMBRANE FUSION OB- SERVED IN SINGLE VIRAL ENVELOPE GLYCOPROTEINS.  Dibyendu Kumar Das, Natasha Durham, Angela Howard, James B. Munro Platform Protein-Lipid Interactions: Channels/Structures 4:00 pm - 6:00 pm, Room 309/310 Co-Chairs Wayland Cheng, Washington University School of Medicine Ololade Fatunmbi, University of Pennsylvania 202-Plat 4:00 pm TOXIC amYLOID TAPE: A NOVEL MIXED ANTIPARALLEL/PARALLEL BETA- SHEET STRUCTURE FORMED BY ABETA ON GM1 CLUSTERS.  Katsumi Matsuzaki , Yuki Okada, Kaori Okubo, Keisuke Ikeda, Yoshiaki Yano, Masaru Hoshino, Yoshio Hayashi, Yoshiaki Kiso, Hikari Itoh-Watanabe, Akira Naito 203-Plat 4:15 pm RECRUITMENT OF ACTIN-BINDING PROTEINS ON THE MEMBRANE INTERFACE: EFFECTS OF CHOLESTEROL ON PROTEIN/PIP2 INTERAC- TIONS.  Ololade Fatunmbi , Ryan Bradley, Robert Bucki, Paul Janmey, Ravi Radhakrishnan 204-Plat 4:30 pm MOLECULAR MECHANISM OF VOLTAGE-GATED CA 2+ CHANNEL REGULA- TION BY MEMBRANE PIP 2 .  Cheon-Gyu Park , Byung C. Suh 205-Plat 4:45 pm PH INDUCED SWITCH BETWEEN DIFFERENT MODES OF CYTOCHROME C BINDING TO CARDIOLIPIN CONTAINING LIPOSOMES.  Bridget Milorey , Reinhard Schweitzer-Stenner 206-Plat 5:00 pm MOLECULAR DYNAMICS SIMULATIONS OF KIR2.2 AND CHOLESTEROL REVEAL STATE- AND CONCENTRATION-DEPENDENT BINDING SITES.  Nicolas Barbera , Manuela A. Ayee, Belinda S. Akpa, Irena Levitan 207-Plat 5:15 pm DIFFUSION IN NANOPORE CONNECTED BILAYER NETWORKS.  Manon Valet , Léa-Laetitia Pontani, Élie Wandersman, Alexis Prevost

185-Plat 5:45 pm CRYO-EM REVEALS TWO DISTINCT SEROTONIN-BOUND CONFORMA- TIONS OF FULL-LENGTH 5-HT3A RECEPTOR.  Sandip Basak , Yvonne W. Gicheru, Shanlin Rao, Mark S. Sansom, Sudha Chakrapani Platform Protein Folding, Pathways, and Stability 4:00 pm - 6:00 pm, Ballroom IV Co-Chairs Taras Pogorelov, University of Illinois at Urbana–Champaign Siwen Zhang, Rensselaer Polytechnic Institute 186-Plat 4:00 pm TRAVEL AWARDEE CHARACTERIZATION OF CONFORMATIONAL DIVERSITY, STABILITY, AND CATALYTIC ACTIVITY OF TCMN, AN ENZYME INVOLVED IN ANTIBIOTIC BIOSYNTHESIS.  Veronica S. Valadares , Luan C. Martins, Lara G. R. V. M. Tannus, Adolfo H. Moraes, Elio A. Cino 187-Plat 4:15 pm INVESTIGATING THE GENERALITY AND BIOPHYSICAL UNDERPINNINGS OF CONSENSUS PROTEIN STABILITY ENHANCEMENT. Matthew Sternke , Katherine W. Tripp, Doug Barrick 188-Plat 4:30 pm PROTEIN-SOLVENT ATTRACTIVE INTERACTIONS DOMINATE THE INVERSE TEMPERATURE DEPENDENCE OF POLYPEPTIDE HYDRATION FREE ENER- GIES.  Tomar S. Tomar, Michael E. Paulaitis, Lawrence R. Pratt, Dilip N. Asthagiri 189-Plat 4:45 pm MULTI-SCALE SIMULATIONS YIELD INSIGHT INTO PROTEIN DIFFUSION AND STABILITY IN CROWDED ENVIRONMENTS.  Stepan Timr , Simone Melchionna, Philippe Derreumaux, Fabio Sterpone 190-Plat 5:00 pm FAST PRESSURE JUMP REVEALS SITE-SPECIFIC PROTEIN DEHYDRATION- FOLDING DYNAMICS. Maxim B. Prigozhin, Yi Zhang, Klaus J. Schulten, Martin Gruebele, Taras V. Pogorelov 191-Plat 5:15 pm SINGLE-MOLECULE FORCE SPECTROSCOPY AND MOLECULAR DYNAM- ICS SIMULATIONS REVEALS COMPLEX FOLDING LANDSCAPE AND ITS POTENTIAL ROLE IN amYLOID FIBRIL FORMATION IN A PDZ DOMAIN.  Ha H. Truong , Susan Marqusee 192-Plat 5:30 pm PROBING PRESSURE EFFECTS ON CORE PACKING OF A REPEAT PROTEIN USING 13C NMR.  Siwen Zhang , Scott McCallum, Catherine A. Royer 193-Plat 5:45 pm CHAPERONE-GUIDED CO-TRANSLATIONAL FOLDING.  Kaixian Liu, Kevin Maciuba , Christian M. Kaiser Platform Spectroscopy and Single-Molecule Fluorescence 4:00 pm - 6:00 pm, Room 307/308 Co-Chairs Julia Widom, University of Oregon Hui-Ting Lee, Johns Hopkins University 194-Plat 4:00 pm FRET-FILTERED SPECTROSCOPY TO SIMULTANEOUSLY PROBE LOCAL AND GLOBAL CONFORMATIONS OF NUCLEIC ACIDS.  Julia R. Widom 195-Plat 4:15 pm TETHERLESS, PRECISE AND EXTENDED OBSERVATION OF SINGLE-MOLE- CULE FRET IN AN ANTI-BROWNIAN TRAP.  Hugh Wilson , Quan Wang

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