Biophysical Society 63rd Annual Meeting | Program Guide

1006-Pos Board B108 MOLECULAR MECHANISMS OF THE INTERACTION BETWEEN THE RNA- BINDING PROTEIN NAB2 AND THE NUCLEAR BASKET PROTEIN MLP1 IN MRNA QUALITY CONTROL. Mohammad Soheilypour , Mohaddeseh Peyro, Hengameh Shams, Stephanie Rider, Ali R. Kaazempur-Mofrad, Mohammad Mofrad Membrane Protein Dynamics I (Boards B109 - B134) 1007-Pos Board B109 SPATIAL CONFINEMENT EFFECTS ON LIPID KINASE AND PHOSPHATASE REACTIONS ON MEMBRANE SURFACES. Albert A. Lee 1008-Pos Board B110 DYNAMIN PH DOMAIN INTERACTIONS WITH LIPID MEMBRANE.  Joseph A. Marte , Dalia Hassan, Frank X. Vazquez 1009-Pos Board B111 BINDING FROM BOTH SIDES: TOLR AND FULL-LENGTH OMPA BIND AND MAINTAIN THE LOCAL STRUCTURE OF THE E. COLI CELL WALL. Alister T. Boags 1010-Pos Board B112 THE OPEN STATE OF THE BAM COMPLEX IS STABILIZED BY ITS ACCESSORY PROTEINS. Zijian Zhang , David Ryoo, Karl Lundquist, James Gumbart 1011-Pos Board B113 TRAVEL AWARDEE INVESTIGATING THE ACTIVATION MECHANISM ALTERATION OF RECEP- TOR TYROSINE KINASE MUTANTS. Soyeon Kim , ZHENFANG DU, Christine Lovly, AdamW. Smith 1012-Pos Board B114 RETINAL FLIPPING DURING RHODOPSIN ACTIVATION REVEALED BY SOLID STATE 2 H NMR AND QM/MM SIMULATIONS. Andrey V. Struts , Mikhail N. Ryazantsev, Xiaolin Xu, Trivikram R. Molugu, Suchithranga M.D.C. Perera, Charitha Guruge, Samira Faylough, Carolina Nascimento, Nasri Nesnas, Michael F. Brown 1013-Pos Board B115 UBIQUITINATION OF MHC II CHANGES DYNAMICS OF ITS RECOGNITION STRUCTURE. Haruo Kozono , Takashi Kawamoto, Yuko Kozono, masahiro kuramochi, Yuji C. Sasaki 1014-Pos Board B116 EXPLORING THE INTERHELICAL LANDSCAPE OF THE Β-2 ADRENERGIC RECEPTOR TO IDENTIFY DRUGGABLE INTERMEDIATE STATES USING ENHANCED-SAMPLING MOLECULAR DYNAMICS AND SITE IDENTIFICA- TION BY LIGAND COMPETITIVE SATURATION (SILCS). Christoffer Lind , Deepak Deshpande, Alexander D. MacKerell 1015-Pos Board B117 STUDY OF ULTRA-FAST RHODOPSIN ACTIVATION DYNAMICS WITH MOLECULAR DYNAMICS SIMULATIONS. Letty Salas , Derek Mendez, José Domingo Meza-Aguilar, Suchithranga M. D. C. Perera, Abhishek Singharoy, Andrey V. Struts, Nadia A. Zatsepin, Richard A. Kirian, Thomas D. Grant, Petra Fromme, Michael F. Brown, Alan Grossfield 1016-Pos Board B118 TRAVEL AWARDEE MOLECULAR SIMULATIONS GIVE INSIGHTS INTO THE NDM-1/MEM- BRANE INTERACTION THAT CAUSES RISE OF A SUPER-BACTERIUM.  Alessio Prunotto , Guillermo Bahr, Lisandro González, Alejandro Vila, Mat- teo Dal Peraro 1017-Pos Board B119 RAF-1 CYSTEINE-RICH DOMAIN (CRD) PROMOTES ACTIVE ORIENTATION AND DIMERIZATION OF KRAS4B AT THE MEMBRANE. Hyunbum Jang , Ruth Nussinov

1018-Pos Board B120 DYNAMIC “MOLECULAR PORTRAITS” OF PROTEINS AND CELL MEM- BRANES: A COMPUTATIONAL VIEW. Roman G. Efremov , Anton A. Polyan- sky, Anton Chugunov, Nikolay A. Krylov, Dmitry Nolde, Pavel E. Volynsky, Andrey Kuznetsov, Pascal Maurice 1019-Pos Board B121 STRUCTURAL INSIGHTS INTO THE SUBTYPE-SELECTIVE ANTAGONIST BINDING TO THE M2 MUSCARINIC RECEPTOR. Sangbae Lee , Suno Ryoji, Maeda Shoji, Takuya Kobayashi, Brian K. Kobilka, Nagarajan Vaidehi 1020-Pos Board B122 INTERPLAY BETWEEN THE CONFORMATIONAL DYNAMICS OF A BACTE- RIAL ABC-TRANSPORTER AND SURROUNDING MEMBRANE MECHANICAL PROPERTIES. Alicia Damm , Su-Jin Paik, Ajay Kumar Mahalka, John Manzi, Daniel Levy, Patricia M. Bassereau, Maxime Dahan 1021-Pos Board B123 INTRAMEMBRANE PROTEOLYSIS BY GAMMA-SECRETASE: EFFICIENCY AS A MATTER OF SUBSTRATE FLEXIBILITY. Philipp A. Högel , Dieter Langosch 1022-Pos Board B124 DRUG PERMEATION ACROSS THE BACTERIAL MEMBRANE: COMBINING THEORETICAL AND EXPERIMENTAL APPROACHES. Paula Gameiro , Carla F. Sousa, João TS Coimbra, Pedro A. Fernandes, Maria J. Ramos 1023-Pos Board B125 TRAVEL AWARDEE DYNAMIC ACTIN MEDIATED NANOCLUSTERING OF CD44 REGULATES ITS MESO-SCALE ORGANIZATION AT THE PLASMA MEMBRANE. Parijat Sil , Sangeeta Nath, Nicolas Mateos, Takahiro Fujiwara, Maria F. Garcia-Parajo, Akihiro Kusumi, Satyajit Mayor 1024-Pos Board B126 TRAVEL AWARDEE G-PROTEIN-COUPLED RECEPTOR ACTIVATION MEDIATED BY INTERNAL HYDRATION. Steven D.E. Fried , Anna R. Eitel, Nipuna Weerasinghe, Caro- lanne E. Norris, Johnathan D. Somers, Gabrielle I. Fitzwater, Michael C. Pitman, Andrey V. Struts, Suchithranga M.D.C. Perera, Michael F. Brown 1025-Pos Board B127 DYNAMICS AND ENERGETICS OF GATING MECHANISM IN MECHANOSEN- SITIVE CHANNEL OF LARGE CONDUCTANCE (MSCL). Rajitha R. Tatikonda , Juan M. Vanegas 1026-Pos Board B128 SELECTIVITY AND SUBSTRATE TRANSLOCATION MECHANISM IN EUKARY- OTIC SWEET PROTEINS: BIOINFORMATICS AND MOLECULAR DYNAMICS STUDIES. Ankita Gupta , Ramasubbu Sankararamakrishnan 1027-Pos Board B129 TOPOGRAPHIC MODULATION OF ACETYLCHOLINE RECEPTORS DIFFU- SION DYNAMICS ON LIVE CELL MEMBRANE. Yusheng Shen , Chengjie Luo, Penger Tong 1028-Pos Board B130 ELECTROMIGRATION OF CELL SURFACE MACROMOLECULES DURING GALVANOTAXIS. Anyesha Sarkar , Brian M. Kobylkevich, David M. Graham, Mark A. Messerli 1029-Pos Board B131 ANALYSIS OF ION CHANNEL DYNAMICS BY SINGLE MOLECULE TRACKING IN LIVE CELLS. Yeonki Hong , Jiseong Park, Daeha Seo 1030-Pos Board B132 GATING MECHANISM OF A POTASSIUM CHANNEL, EXPERIMENTAL AND THEORETICAL STUDIES. Charline Fagnen , Ludovic Bannwarth, Iman Oubella, Yasmina Mhoumadi, Aline De Araujo, Eric Forest, David Parahia, Catherine Vénien-Bryan

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