Biophysical Society 63rd Annual Meeting | Program Guide

1155-Pos Board B257 MECHANISM OF EPHA2 DIMERIZATION IN RESPONSE TO MONOMERIC LI- GANDS. Elmer A. Zapata-Mercado , Randall Rainwater, Elena B. Pasquale, Kalina Hristova 1156-Pos Board B258 INVESTIGATING THE ROLE OF THE TRANSMEMBRANE HELIX OF EPHA2 IN SIGNAL TRANSDUCTION ACROSS THE PLASMA MEMBRANE. Daniel Wirth , Kalina Hristova, Elena Pasquale 1157-Pos Board B259 THERMODYNAMICS AND KINETICS OF THE DIVALENT-MONOVALENT CATION COMPETITION FOR BINDING SITES AT THE µ-OPIOID RECEP- TOR. Xiaohu Hu , Davide Provasi, Marta Filizola 1158-Pos Board B260 DETECTING INTRAMOLECULAR DYNAMICS OF GPCR S USING DIFFRACTED X-RAY BLINKING TECHNIQUE. Kazuhiro Mio , Masaki Ishihara, Shoko Fujimura, Masahiro Kuramochi, Yuji C. Sasaki 1159-Pos Board B261 INTER-DOMAIN INTERACTIONS AND ALLOSTERIC MODULATION OF METABOTROPIC GLUTAMATE RECEPTORS. Vanessa Gutzeit, Jordana Thibado, Josh T. Levitz 1160-Pos Board B262 CONFORMATIONAL FREE ENERGIES OF METABOTROPIC GLUTAMATE RECEPTOR LIGAND-BINDING DOMAINS. Tyler J. Wied 1161-Pos Board B263 TRAVEL AWARDEE MECHANISMS OF G PROTEIN-SELECTIVITY IN MUSCARINIC ACETYLCHO- LINE RECEPTOR FAMILY. Luis Santiago , Ravinder Abrol 1162-Pos Board B264 THE ROLE OF PROTEIN PHOSPHATASE 2A IN THE RE-SENSITIZATION OF MELANOPSIN DURING CONTINUED LIGHT STIMULATION.  Juan C. Valdez-Lopez , Meheret Gebreeziabher, Jair Flores, Olanike Awotunde, Thomas Burnett, Adam Byerly, Phyllis R. Robinson 1163-Pos Board B265 MODULATION OF MU-OPIOID RECEPTOR SIGNALING BY CANNABINOID CB1 RECEPTOR THROUGH HETEROMERIZATION, A NOVEL ANALGESIC TARGET. Guoqing Xiang , Lia Baki, Takeharu Kawano, Diomedes Logothetis 1164-Pos Board B266 CANNABINOID RECEPTOR CB2 OLIGOMERIZATION IN A LIPID MA- TRIX. Alexei Yeliseev, Jonathan D. Nickels, Kirk G. Hines, Lioudmila Zoubak, Walter E. Teague, Jr., Diane L. Lynch, Dow P. Hurst, Kevin L. Weiss, John Katsaras, Patricia H. Reggio, Klaus Gawrisch 1165-Pos Board B267 THE INTERPLAY OF STRUCTURAL AND CELLULAR BIOPHYSICS CON- TROLS THE CLUSTERING OF MULTIVALENT SIGNALING MOLECULES: THE NEPHRIN-NCK-NWASP SYSTEM. Aniruddha Chattaraj , Leslie M. Loew 1166-Pos Board B268 ALLOSTERISM IN OLIGOMERIC RECEPTOR MODELS: CYCLE BASES OF REDUCED GRAPH POWERS PROVIDE A THEORETICAL FRAMEWORK FOR CONFORMATIONAL COUPLING. Greg Conradi Smith 1167-Pos Board B269 QUANTIFICATION OF SURFACE RECEPTOR-ACTIN CORTEX INTERPLAY VIA TWO-COLOR HIGH RESOLUTION IMAGING. Aparajita Dasgupta , Deryl Tschoerner, Bruno Da Rocha-Azevedo, Khuloud Jaqaman

1143-Pos Board B245 COMBINING SYSTEMS PHARMACOLOGY MODELING WITH MACHINE LEARNING TO IDENTIFY SUB-POPULATIONS AT RISK OF ARRHYTH- MIA. Meera Varshneya , Xueyan Mei, Eric A. Sobie 1144-Pos Board B246 3-WEEK-OLD RABBIT CARDIOMYOCYTES (3WRBCM): A NOVEL CELLULAR MODEL FOR STUDYING CARDIAC EXCITATION. Anatoli Y. Kabakov , Karni Moshal, YiChun Lu, Karim Roder, Turan Nilufer, Weiyan Li, Kevin Murphy, Dmitry Terentyev, Gideon Koren 1145-Pos Board B247 A COMPARATIVE ANALYSIS OF PARAMETER ESTIMATION STRATEGIES FOR MATHEMATICAL MODELING OF ION CHANNEL GATING. Chiara Campana , Eric A. Sobie 1146-Pos Board B248 THE EFFECTS OF FREQUENCY OF VOLUNTARY EXERCISE ON CARDIAC FUNCTION IN DILATED CARDIOMYOPATHY MODEL MICE. Masami Sugihara , Ryo Kakigi, Takashi Murayama, Takashi Miida, Takashi Sakurai, Sachio Morimoto, Nagomi Kurebayashi 1147-Pos Board B249 HIGH RESOLUTION IMAGING AND HISTOPATHOLOGICAL CHARACTERIZA- TION OF MYOCARDIAL INFARCTION. Peter Lin, Jared Westreich, Mengyu- an Li, Adam Gribble, Susan Newbigging, Alex Vitkin, Mihaela Pop 1148-Pos Board B250 TRAVEL AWARDEE SINUS BRADYCARDIA DUE TO ELECTROLYTE CHANGES AS A POTENTIAL PATHOMECHANISM OF SUDDEN CARDIAC DEATH IN HEMODIALYSIS PATIENTS. Axel Loewe , Yannick Lutz, Alan Fabbri, Stefano Severi 1149-Pos Board B251 EFFECTS OF VARYING TRANSVERSE AND AXIAL TUBULES IN A THREE- DIMENSIONAL MODEL OF CALCIUM SIGNALING IN THE HUMAN ATRIAL MYOCYTE. Xianwei Zhang , Haibo Ni, Stefano Morotti, Daisuke Sato, Eleonora Grandi 1150-Pos Board B252 TRAVEL AWARDEE DISRUPTION OF CAVEOLAR MICRODOMAINS CREATES “HOT SPOTS” FOR ATRIAL ECTOPY AND ARRYTHMOGENESIS IN HEART FAILURE MICE. Di Lang , Leonid Tyan, Aleah Warden, Zachary D. Piro, Rylie Lodin, Evi Lim, Ashley Irwin, Alexey V. Glukhov Membrane Receptors and Signal Transduction I (Boards B253 - B269) 1151-Pos Board B253 MET RECEPTOR TYROSINE KINASE ACTIVATION STUDIED AT THE SINGLE- MOLECULE LEVEL. Marina S. Dietz , Marie-Lena I.E. Harwardt, Thorsten Wohland, Hartmut H. Niemann, Mike Heilemann 1152-Pos Board B254 TRAVEL AWARDEE SPATIOTEMPORAL DYNAMICS OF RON AND EGFR CROSSTALK AT THE PLASMA MEMBRANE.  Justine Keth , Carolina Franco Nitta, Elton D. Jham- ba, Ellen W. Hatch, Mara P. Steinkamp, Bridget S. Wilson, Diane S. Lidke 1153-Pos Board B255 PROBING THE INTERACTION BETWEEN RECEPTOR TYROSINE KINASES AND TRANSMEMBRANE ADHESION PROTEINS. Taylor P. Light , Deborah Leckband, Kalina Hristova 1154-Pos Board B256 RESPONSE OF FGFR1 TO DIFFERENT LIGANDS. Kelly Karl

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