Biophysical Society 63rd Annual Meeting | Program Guide

No Abstract 12:16 pm EXPLORING THE RIBOSOME WITH FRIENDS: MYSTERIES OF THE MOTHER SHIP.  Harry Noller No Abstract 12:29 pm A (SCIENTIFIC) LIFETIME AFFAIR WITH NUCLEIC ACIDS.  Juli Feigon Platform Systems Biology and Genetic Regulatory Networks 10:45 am - 12:45 pm, Ballroom II Co-Chairs Amelia Palermo, The Scripps Research Institute Samuel Schaffter, Johns Hopkins University 1512-Plat 10:45 am SYNTHETIC INTEGRATED IN VITRO TRANSCRIPTIONAL REGULATORY NET- WORKS.  Samuel Schaffter , Rebecca Schulman 1513-Plat 11:00 am A LIVING, SINGLE CELL VIEW OF MYC’S EFFECTS ON TRANSCRIPTION.  Simona Patange , Michelle Girvan, David Levens, Daniel R. Larson 1514-Plat 11:15 am QUANTITATIVE ANALYSIS OF A TRANSIENT DYNAMICS OF A GENETIC REGULATORY NETWORK.  Julian Lee , JeJun Lee 1515-Plat 11:30 am THE IMPACT OF ALLELIC IMBALANCE ON SIGNAL TRANSMISSION STRONGLY DEPENDS ON NETWORK MOTIF PROPERTIES.  Shibin Mathew, Alexander Gimelbrant, Suzanne Gaudet 1516-Plat 11:45 am CAPTURING METABOLISM-DEPENDENT SOLVENT POLARITY FLUC- TUATIONS IN A TRAFFICKING LYSOSOME.  Filippo Begarani, Francesca D’Autilia, Giovanni Signore, Enrico Gratton, Fabio Beltram, Francesco 12:00 pm LAT VESICLES WORK AS A SIGNAL TRANSDUCTION PLATFORM IN IM- MUNE CELLS; UNRAVELING BY SINGLE-MOLECULE IMAGING.  Koichiro M. Hirosawa , Nao Hiramoto-Yamaki, Kenta J. Yoshida, Shohei Nozaki, Taka A. Tsunoyama, Bo Tang, Kenichi G.N. Suzuki, Kazuhisa Nakayama, Takahiro K. Fujiwara, Akihiro Kusumi 1518-Plat 12:15 pm 4D CHARACTERIZATION OF SPATIOFUNCTIONAL ENZYME DROPLETS IN LIVING CELLS. Minjoung Kyoung 1519-Plat 12:30 pm TRAVEL AWARDEE A NETWORK OF ENDOGENOUS METABOLITES MODULATES PRO- GRAMMED DEATH-LIGAND 1 (PD-L1) EXPRESSION IN MONOCYTIC LEUKEMIA.  Amelia Palermo , Stephan Spangenberg, Carlos Guijas, Luke Lairson, Gary Siuzdak Platform Cardarelli 1517-Plat Co-Chairs Carolyn Moores, Birkbeck College, London, United Kingdom Andrea Serra-Marques, University of California, San Francisco 1520-Plat 10:45 am CRYO-EM REVEALS THE CHEMO-MECHANICAL COUPLING OF THE ONCO- GENIC KINESIN-3 KIF14. Matthieu P.M.H. Benoit , Ana B. Asenjo, Moham- madjavad Paydar, Benjamin H. Kwok, Hernando Sosa Microtubule-based Motors 10:45 am - 12:45 pm, Ballroom III

1521-Plat 11:00 am HOW KINESIN-2 MOTORS WORK TOGETHER?  Punam Sonar , Willi L.

Stepp, Zeynep Ökten 1522-Plat 11:15 am

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THE CRYO-EM STRUCTURE AND ACTIVITY OF KINESIN-5 FROM PLASMO- DIUM FALCIPARUM: MECHANISTIC LESSONS FROM A PARASITE KINESIN.  Alex D. Cook , Anthony J. Roberts, Maya Topf, Carolyn A. Moores 1523-Plat 11:30 am TAU DIFFERENTIALLY REGULATES KINESIN-1, KINESIN-2, AND KINESIN-3.  Dominique V. Lessard , Christopher L. Berger 1524-Plat 11:45 am INVESTIGATION OF COLLISIONS OF MICROTUBULES DRIVEN BY NANO- PATTERNED KINESINS.  Tamanna Ishrat Farhana , Taikopaul Kaneko, Ryuji 12:00 pm MECHANISMS OF ASTRAL MICROTUBULE REGULATION BY KINESIN MO- TOR PROTEINS.  Toni Mchugh , Agata A. Gluszek, Julie P.I. Welburn 1526-Plat 12:15 pm KINESINS 1 AND 3 COOPERATE ON THE SAME VESICLE TO TRANSPORT EXOCYTOTIC CARRIERS.  Andrea Serra-Marques , Maud Martin, Eugene Katrukha, Ilya Grigoriev, Qingyang Liu, Lotte Pedersen, Lukas Kapitein, Anna Akhmanova 1527-Plat 12:30 pm DYNEIN’S DIRECTIONALITY IS CONTROLLED BY THE ANGLE AND LENGTH OF ITS STALK.  Sinan Can , Samuel Lacey, Mert Gur, Andrew Carter, Ahmet Yildiz Platform Protein Structure and Conformation III 10:45 am - 12:45 pm, Ballroom IV Co-Chairs Justin MacCallum, University of Calgary, Canada Lauren Porter, Howard Hughs Medical Institute 1528-Plat 10:45 am DETERMINING PROTEIN STRUCTURES BY ITERATING BETWEEN COMPU- TATION AND EXPERIMENT.  Justin L. MacCallum , Kari Gaalswyk 1529-Plat 11:00 am EXPOSING THE NUCLEATION SITE OF ALPHA HELIX FOLDING: A JOINT EXPERIMENTAL AND SIMULATION STUDY.  Arusha Acharyya , Yunhui Ge, Haifan Wu, William DeGrado, Vincent Voelz, Feng Gai 1530-Plat 11:15 am MOLECULAR DYNAMICS SIMULATIONS OF THE CIRCADIAN CLOCK PROTEIN KAIC REVEAL STRUCTURAL INSIGHTS INTO THE NUCLEOTIDE RELEASE AND CIRCADIAN TIMING MECHANISMS.  Lu Hong , Bodhi P. Vani, Erik H. Thiede, Michael J. Rust, Aaron R. Dinner 1531-Plat 11:30 am CHARACTERIZATION OF PROTEIN STRUCTURAL CHANGES USING A NOVEL NONLINEAR OPTICAL TECHNIQUE.  Bason Clancy , Ben Moree, Joshua Salafsky 1532-Plat 11:45 am TOWARDS ATOMIC-RESOLUTION STRUCTURE DETERMINATION OF HIV-1 CAPSID ASSEMBLIES USING MAGIC ANGLE SPINNING NMR. Manman Lu , Mingzhang Wang, Jochem Struppe, Werner Maas, Angela Gronenborn, Tatyana Polenova 1533-Plat 12:00 pm KINDLIN DIMER STRENGTHENS FOCAL ADHESIONS UNDER FORCE BY RELIEVING AND MEDIATING INTRACELLULAR CROSSTALK AMONG INTE- GRINS.  Zeinab Jahed, Zainab Haydari, Akshay Rathish, Mohammad R. K. Mofrad Yokokawa 1525-Plat

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