Biophysical Society 65th Annual Meeting Program Guide

Platform Membrane Physical Chemistry 10:00 am - 11:30 am

Platform Microtubules, Structure, Dynamics, and Associated Proteins 10:00 am - 11:30 am Chair Samara Reck-Peterson, University of California, San Diego, USA 53-Plat 10:00 am MECHANISM OF PARKINSON’S DISEASE-LINKED LRRK2’S INTERACTION WITH MICROTUBULES. Samara L. Reck-Peterson , David Snead, Mariusz Matyszewski, Andrea M. Dickey, Yu Xuan Lin, Andres Leschziner 54-Plat 10:30 am AUTOREGULATORY CONTROL OF MICROTUBULE BINDING IN DOUBLE- CORTIN-LIKE KINASE 1. Melissa Rogers, Tracy Tan, Amrita Ramkumar, Ashlyn Downing, Hannah Bodin, Julia Castro, Dan W. Nowakowski, Kassandra M. Ori-McKenney 55-Plat 10:45 am LOAD-BEARING INTERACTIONS BETWEEN THE NDC80 AND DAM1 COM- PLEXES DIFFER ON GROWING AND SHORTENING MICROTUBULE TIPS. Rachel L. Flores , Zachary Peterson, Charles L. Asbury, Trisha Davis 56-Plat 11:00 am CLASPS DEPOLYMERIZE MICROTUBULES IN A NUCLEOTIDE-DEPENDENT MANNER. Elizabeth J. Lawrence , Marija Zanic 57-Plat 11:15 am GTP-DEPENDENT FORMATION OF STRAIGHT OLIGOMERS LEADS TO NUCLEATION OF MICROTUBULES. Etsuko Muto , Rie Ayukawa, Seigo Iwata, Hiroshi Imai, Shinji Kamimura, Ken Sekimoto, Gigant Benoît Platform Optical Microscopy and Superresolution Imaging I 10:00 am - 11:30 am Chair Erdinc Sezgin, Karolinska Institute, Sweden No Abstract 10:00 am UNDERSTANDING PLASMA MEMBRANE WITH SUPERRESOLUTION IMAG- ING AND SPECTROSCOPY. Erdinc Sezgin 58-Plat 10:30 am DIRECTIONALITY OF LIGHT ABSORPTION AND EMISSION IN FLUORES- CENT PROTEINS. Jitka Myskova, Olga Rybakova, Jiri Brynda, Petro Khoro- shyy, Alexey Bondar, Josef Lazar 59-Plat 10:45 am QUANTITATIVE SUPERRESOLUTION IMAGING OF EFFLUX PUMPS IN BIOFILM-ASSOCIATED BACTERIA. Lucia Gardini , Tiziano Vignolini, Marco Capitanio, Francesco S. Pavone 60-Plat 11:00 am FLUOROGENIC PROBE FOR FAST 3D WHOLE-CELL DNA-PAINT. Kenny K.H. Chung , Zhao Zhang, Phylicia Kidd, Yongdeng Zhang, Nathan D. Wil- liams, Bennett Rollins, Yang Yang, Chenxiang Lin, David Baddeley, Joerg Bewersdorf 61-Plat 11:15 am HIGH-THROUGHPUT SUPER-RESOLUTION MICROSCOPY OF VIRAL PAR- TICLES REVEALS INSIGHTS INTO THEIR MORPHOLOGY AND ORGANISA- TION. AndrewMcMahon , Christof Hepp, Nicole C. Robb

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Chair Tobias Walther, Harvard University, USA 43-Plat 10:00 am THE PHASE OF FAT: MECHANISMS AND REGULATION OF LIPID STORAGE. Robert V. Farese, Tobias Walther 44-Plat 10:30 am CLATHRIN SENSES MEMBRANE CURVATURE. Wade F. Zeno , Jacob B. Hochfelder, Ajay S. Thatte, Liping Wang, Avinash K. Gadok, Carl Hayden, Eileen M. Lafer, Jeanne C. Stachowiak 45-Plat 10:45 am ALPHA-SYNUCLEIN AFFECTS DIFFERENTLY THE INTERNAL AND EXTERNAL LEAFLET OF THE LIPID MEMBRANES. Samira Jadavi , Silvia Dante, Alberto Diaspro, Claudio Canale 46-Plat 11:00 am INSERTING SMALL MOLECULES ACROSS MEMBRANE MIXTURES: INSIGHT FROM THE POTENTIAL OF MEAN FORCE. Tristan Bereau 47-Plat 11:15 am TAKING A COOLER BREATH: MODERATE HYPOTHERMIA BOOSTS LUNG SURFACTANT ACTIVITY. Chiara Autilio , Mercedes Echaide, Emilie Da Silva, Jorid Birkelund Sørli, Jesus Perez-Gil Platform Voltage-gated Channels 10:00 am - 11:30 am Chair Teresa Giraldez, University of La Laguna, Spain 48-Plat 10:00 am INSIGHTS INTO THE FUNCTION OF BK-CA MULTI-CHANNEL COMPLEXES. Teresa Giraldez 49-Plat 10:30 am FUNCTIONAL CHARACTERIZATION OF DISEASE-CAUSING MUTATIONS IN THE SODIUM LEAK CHANNEL NALCN. Claudia Weidling , Aishat O. Ameen, Han Chow Chua, Stephan A. Pless 50-Plat 10:45 am COTRANSLATIONAL COMPLEXES ENCODING ION CHANNELS IN THE HEART. Margaret B. Jameson , Catherine A. Eichel, Fang Liu, Erick B. Rios Perez, David K. Jones, Gail A. Robertson 51-Plat 11:00 am SINGLE-MOLECULE RESOLUTION OF MULTIVALENT LIGAND BINDING IN PACEMAKER CHANNELS. David S. White , Sandipan Chowdhury, Ruohan Zhang, Scott T. Retterer, Randall H. Goldsmith, Baron Chanda 52-Plat 11:15 am INFLUENCE OF PHOSPHOLIPID BINDING ON VOLTAGE SENSOR-PORE COUPLING IN THE KAT1 POTASSIUM CHANNEL. Bernardo I. Pinto , Mi- chael D. Clark, Eduardo Perozo, Francisco Bezanilla

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