Biophysical Society 65th Annual Meeting Program Guide

147-Pos B oard B81 CURVATURE SENSING MEDIATED BY F-BAR DOMAIN AND AN INTRINSI- CALLY DISORDERED REGION OF FBP17. Maohan Su , Yinyin Zhuang, Wenting Zhao, Min Wu 148-Pos B oard B82 TAU FORMS OLIGOMERIC COMPLEXES ON MICROTUBULES THAT ARE DISTINCT FROM PATHOLOGICAL OLIGOMERS IN DISEASE. Melina Theoni Gyparaki , Arian Arab, Elena M. Sorokina, Adriana N. Santiago- Ruiz, Christopher H. Bohrer, Jie Xiao, Melike Lakadamyali 149-Pos B oard B83 THE C55 PEPTIDE PORTION OF THE AMYLOID PRECUROSR PROTEIN CAN FORM STABLE DIMERS. Ethan Croitoru , Esmael J. Haddadian 150-Pos B oard B84 ACCELERATED AMYLOID BETA PATHOGENESIS BY BACTERIAL AMYLOID FAPC. Zhenzhen Zhang , Feng Ding 151-Pos B oard B85 LIQUID-LIQUID PHASE SEPARATION IS INFLUENCED BY THE ACTIVE, CROWDED CYTOPLASM. Tong Shu , Jonathan Alberts, Dajun Sang, Sarah Tsao, Matheus Palhares Viana, Meta Heidenreich, Emmanuel Levy, Liam J. Holt 152-Pos B oard B86 EFFECTS OF THE FLANKING POLYQ REGIONS AND MEMBRANE PHYSICAL PROPERTIES ON HUNTINGTIN BINDING TO LIPID VESICLES. Tânia Sousa, Nuno Bernardes, Ana Coutinho, Manuel Prieto, Ana M. Melo 153-Pos B oard B87 THE SEQUENCE, STRUCTURE AND FUNCTION OF THE PLANT STRESS PROTEIN LEA3. Karamjeet K. Singh, Steffen P. Graether DNA Replication, Recombination, and Repair (Boards B88 - B95) 154-Pos B oard B88 USING EXCITON-COUPLED PROBE SPECTROSCOPY TO INVESTIGATE THE ROLES OF LOCAL DNA CONFORMATIONAL DYNAMICS IN PROCESSIVE DNA POLYMERASE HOLOENZYME FORMATION. Patrick J. Herbert , Dylan Heussman, Jack Maurer, Steven E. Weitzel, Peter H. von Hippel, Andrew H. Marcus 155-Pos B oard B89 SILVER NANOPARTICLES INTERFERCE WITH DNA REPLICATION IN MITO- CHONDRIA. Yeying Gao , Yujie Zhang, Yun Ju, Xueling Peng, Qingdai Liu 156-Pos B oard B90 EXPLORING THE TRANSLOCATION MECHANISM OF BACTERIOPHAGE T7 HELICASE. Shikai Jin , Carlos A. Bueno Basurco, Wei Lu, Yang Gao, Peter G. Wolynes 157-Pos B oard B91 SINGLE-MOLECULE INVESTIGATION OF RAD-51 PRESYNAPTIC FILAMENT ASSEMBLY AND THE ROLE OF MEDIATOR PROTEINS. Ondrej Belan , Con- suelo Barroso, Artur Kaczmarczyk, Roopesh Anand, Stefania Federico, Nicola O’Reilly, Matt D. Newton, Radoslav Enchev, Enrique Martinez- Perez, David S. Rueda, Simon Boulton 158-Pos B oard B92 SINGLE MOLECULE EXPERIMENTS DEFINE THE ROLE OF NBS1 AND XRS2 IN DNA TETHERING BY MRN AND MRX IN DSB REPAIR. Carl Möller , Rajhans Sharma, Robin Öz, Giordano Reginato, Elda Cannavò, Sriram KK, Petr Cejka, Fredrik Westerlund 159-Pos B oard B93 ACTIVATION BARRIERS FOR ADENINE METHYLATION BY METHANE DIAZONIUM ION AND DIMETHYL SULFATE. George A. Papadantonakis , Daniel R. Eichler, Maria V. Yermolina, Tim Regan, Blake Mirman

160-Pos B oard B94 PROBING THE BIOMECHANICS OF RUVA-HOLLIDAY JUNCTION COM- PLEX. Soma Dhakal , Dalton R. Gibbs 161-Pos B oard B95 FLOWMAGNETIC TWEEZERS: IMAGING RARE ENZYMATIC EVENTS WITH SINGLE MOLECULE PRECISION. Rohit Agarwal, Karl E. Duderstadt Protein-Nucleic Acid Interactions I (Boards B96 - B117) 162-Pos B oard B96 DNA FOLDING BY MULTIVALENT CATIONS. Donna M. Roscoe , Ashwin Balaji, Luka Matej Devenica, Ashley R. Carter 163-Pos B oard B97 DNA TOROIDS FORM VIA A FLOWER INTERMEDIATE. Ryan B. McMillan , Hilary Bediako, Luka Matej Devenica, Yuxing E. Ma, Donna M. Roscoe, Ashley R. Carter 164-Pos B oard B98 ELUCIDATION OF INTERACTIONS BETWEEN INTEGRATION HOST FACTOR AND A DNA FOUR-WAY JUNCTION. Shawn H. Lin , Dacheng Zhao, Ishita Mukerji, Candice M. Etson 165-Pos B oard B99 SINGLE MOLECULE INVESTIGATIONS OF PROTEIN AND SMALL MOL- ECULE INTERACTIONS WITH G-QUADRUPLEXES AND THEIR IMPACT ON TELOMERE STRUCTURE. Hamza Balci , GolamMustafa, Prabesh Gyawali, Parastoo Maleki, Sajad A. Shiekh 166-Pos B oard B100 DNA FOLDING BY THE SARS-COV-2 NUCLEOCAPSID PROTEIN. Youna N. Choi , Ryan B. McMillan, Ashley R. Carter 167-Pos B oard B101 DNA STRETCHING AND SUPERCOILING INDUCES CAS9 OFF-TARGET ACTIVITY. Matt D. Newton , Graeme King, Benjamin J. Taylor, Emanuela M. Cuomo, David S. Rueda 168-Pos B oard B102 LINE-1 ORF1P REORGANIZES AND PACKAGES SINGLE-STRANDED NUCLEIC ACIDS THROUGH WRAPPING AND INTERPROTEIN INTERAC- TIONS. Benjamin A. Cashen , M. Nabuan Naufer, Michael D. Morse, Charlie E. Jones, Anthony V. Furano, Mark C. Williams 169-Pos B oard B103 MAPPING THE INTERPLAY BETWEEN DNA TOPOLOGY AND SEQUENCE ON TYPE II TOPOISOMERASE BINDING AND CLEAVAGE ACTIVITY. Rachel Kim , Shannon J. Mckie, Keir C. Neuman 170-Pos B oard B104 DNA-UNWINDING DYNAMICS OF ESCHERICHIA COLI UVRD LACKING THE C-TERMINAL 40 AMINO ACIDS. Hiroaki Yokota 171-Pos B oard B105 E. COLI SINGLE STRANDED BINDING PROTEIN (SSB) BINDING MEASURED USING FORCE SPECTROSCOPY AND STRUCTURAL MUTANTS. Gudfridur B. Moller , M. Nabuan Naufer, Michael Morse, James McIsaac, Ioulia F. Rouzina, Penny Beuning, Mark C. Williams 172-Pos B oard B106 CRITICAL ROLE OF N AND C TERMINAL DOMAINS OF BACTERIOPHAGE T4 SINGLE-STRANDED BINDING PROTEIN (GP32) IN TRANSIENT BINDING CONFORMATIONS AND REORGANIZATION MEASURED USING FORCE SPECTROSCOPY. Benjamin Cashen, Michael Morse , Richard L. Karpel, Ioulia F. Rouzina, Mark C. Williams

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