Biophysical Society 65th Annual Meeting Program Guide

303-Pos B oard B237 MANDIBULAR MUSCLE TROPONIN OF THE FLORIDA CARPENTER ANT CAMPONOTUS FLORIDANUS : EXTENDING OUR INSIGHTS INTO INVER- TEBRATE CA 2+ REGULATION. Yun Shi , Julia P. Bethea, Hannah L. Hetzel- Ebben, Maicon Landim-Vieira, Ross J. Mayper, Regan L. Williams, Lauren E. Kessler, Amanda M. Ruiz, Kathryn Gargiulo, Jennifer S.M. Rose, Grayson Platt, J. Renato D. Pinto, Brian K. Washburn, Prescott B. Chase 304-Pos B oard B238 TIME-RESOLVED X-RAY DIFFRACTION STUDIES ON TWITCHING RAT SOLEUS AND EDL MUSCLE. Henry Gong, Weikang Ma, Michael Regnier, Thomas C. Irving 305-Pos B oard B239 EMBRYONIC MYOSIN MUTATIONS T178I AND R672C DEVELOP MECHANI- CAL DYSFUNCTION WHEN EXPRESSED IN HIPSC DERIVED SKELETAL MYOTUBES. Saffie Mohran , Shawn M. Luttrell, Kati Buckingham, Alec S.T. Smith, Michael J. Bamshad, David L. Mack, Michael Regnier 306-Pos B oard B240 NANOINDENTATION OF IPSC-DERIVED AORTIC SMOOTH MUSCLE CELLS REVEALS A BIOMECHANICAL AND DEVELOPMENTAL BASIS FOR ANEU- RYSM LOCALIZATION IN MARFAN SYNDROME. Robert J. Wiener , Chris- toph Schaniel, Francesco Ramirez, Kevin D. Costa B oard B241 EPITHELIAL CELLS RECOVER SUBSTRATE ADHESION THROUGH RETRAC- TION FIBER-GUIDED LAMELLIPODIA. Elgin Korkmazhan , Carlos O. Garzon Coral, Claudia G. Vasquez, Alexander R. Dunn 308-Pos B oard B242 FIBROBLASTS CLOSE A VOID IN FREE SPACE BY A PURSE-STRING MECHA- NISM. Avelino D.S. Da Costa 309-Pos B oard B243 CELL MONOLAYER DEFORMATION MICROSCOPY - A NEWMETHOD TO MEASURE THE RHEOLOGY OF CELL MONOLAYERS REVEALS MECHANICAL FRAGILITY OF THE CELL NETWORK IN THE EPITHELIAL TO MESENCHYMAL TRANSITION. Amy A. Sutton , Allen J. Ehrlicher, Clayton W. Molter, Ali Amini, Johanan Idicula, Max Furman, Pouria Tirgar Bahnamiri, Yuanyuan Tao, Ajinkya Ghagre, Newsha Koushki, Adele Khavari 310-Pos B oard B244 ACTIVE VOLUME REGULATION IN ADHERED CELLS. RamM. Adar , Samuel Safran 311-Pos B oard B245 GLYCOLYSIS INHIBITION REGULATES ENDOTHELIAL JUNCTIONS BY PER- TURBING ACTIN AND FOCAL ADHESIONS. Gregory Schwarz , Priyanka Gajwani, Jalees Rehman, Deborah E. Leckband 312-Pos B oard B246 MECHANO-ACTIVATION OF MESENCHYMAL STEM CELLS BY AVOIDING INTRACELLULAR TENSIONAL EQUILIBRIUM ON MATRIX WITH STIFFNESS- HETEROGENEITY. Satoru Kidoaki , Hiroyuki Ebata, Kousuke Moriyama, Thasaneeya Kuboki, Yukie Tsuji, Rumi Sawada, Ken Kono, Kazusa Tanaka 313-Pos B oard B247 VERTEX MODEL INSTABILITIES IN EPITHELIAL TISSUES SUBJECT TO CEL- LULAR ACTIVITY OR APPLIED STRESS. Fernanda L. Pérez 314-Pos B oard B248 MACROPHAGES SUPPORT THE AGGRESSIVE MECHANICAL PHENOTYPE OF CIRCULATING TUMOR CELLS IN PROSTATE CANCER. Pawel A. Osmulski , Alessandra Cunsolo, Yusheng Qian, Meizhen Chen, Chun-Lin Lin, Chia-Nung Hung, DevalingamMahalingam, Nameer Kirma, Chun- Liang Chen, Josephine Taverna, Michael Liss, Ian M. Thompson, Tim H.-. Huang, Maria Gaczynska Cell Mechanics, Mechanosensing, and Motility I (Boards B241 - B264) 307-Pos

315-Pos B oard B249 ON THE ADHESION-VELOCITY RELATION AND LENGTH ADAPTION OF MO- TILE CELLS ON STEPPED FIBRONECTIN LANES. Behnam Amiri , Christoph Schreiber, Johannes Heyn, Martin Falcke, Joachim O. Rädler 316-Pos B oard B250 MEDIO-APICAL TENSIONS REGULATE TIGHT JUNCTIONS OF WELL-POLAR- IZED MADIN-DARBY CANINE KIDNEY CELLS. Chia-hsuan Lu, Keng-hui Lin 317-Pos B oard B251 PATTERN-BASED CONTRACTILE SCREENING (PACS), A REFERENCE-FREE TRACTION FORCE MICROSCOPY METHODOLOGY, REVEALS CONTRAC- TILE DIFFERENCES IN BREAST CANCER CELLS. Ajinkya Ghagre , Ali Amini, Luv Kishore Srivastava, Pouria Tirgar Bahnamiri, Adele Khavari, Newsha Koushki, Allen J. Ehrlicher 318-Pos B oard B252 KINETICS OF CELLULAR AGGREGATION MEDIATED THROUGH DIFFERENT KIND OF INTERACTION MECHANISMS. Rumi De , Debangana Mukhopad- hyay 319-Pos B oard B253 DISRUPTING ELKIN1-DEPENDENT MECHANOELECTRICAL TRANSDUC- TION MODULATES CELL-CELL INTERACTIONS IN ORGANOTYPIC TUMOUR SPHEROIDS. Amrutha Patkunarajah , Lioba Schroeter, Georgina Sander- son, Maté Biro, Kate Poole 320-Pos B oard B254 MULTIMODAL MICROSCALE MECHANICAL MAPPING OF SINGLE CELLS AS A FUNCTION OF ENVIRONMENT GEOMETRY. Milos Nikolic , Giuliano Scarcelli, Kandice Tanner 321-Pos B oard B255 MECHANICAL COMPETITION TRIGGERED BY INNATE IMMUNE SIGNAL- ING DRIVES THE COLLECTIVE EXTRUSION OF BACTERIALLY-INFECTED EPITHELIAL CELLS. Effie Bastounis , Francisco Serrano Alcalde, Prathima Radhakrishnan, Patrik Engström, Maria Gómez Benito, Mackenzi Oswald, Jason Smith, MatthewWelch, José M. García Aznar, Julie Theriot 322-Pos B oard B256 WHICH CHEMOTHERAPY DRUGS ALTER CELL MECHANICAL PROPERTIES WITH IMPACT ON METASTASIS? Ashley Abraham, Mackenzie McCuddin, Chisom Nwakama, Megha Jacob, Gargee Khaparde, Scott Baumel, Spen- cer Mckinley, Jack Lewison, Sukhman Virdi, Destiny Jordan, Harry Kramer, Andrew E. Ekpenyong 323-Pos B oard B257 FORCE MEASUREMENT DETERMINES THE DIERECTION OF CELL MIGRA- TION BY THE TRACTION FORCE MICROSCOPY. Takeshi Sakamoto , Yuwen Mei, Justin J. Raupp 324-Pos B oard B258 INTEGRIN CROSSTALK MODULATES STIFFNESS-INDEPENDENT MOTILITY IN CD4+ T LYMPHOCYTES. Sarah Hyun Ji Kim , Daniel A. Hammer 325-Pos B oard B259 DEPENDENCE OF NEUTROPHIL PHAGOCYTOSIS MECHANICS ON EXTRA- AND INTRACELLULAR CALCIUM. Emmet A. Francis , Volkmar Heinrich 326-Pos B oard B260 STRATEGIES OF MECHANICAL ADAPTATION OF CTCS TO BLOOD CIRCU- LATION. Yusheng Qian , Alessandra Cunsolo, Meizhen Chen, Chia-Nung Hung, Nameer B. Kirma, Michael Liss, Tim H. Huang, Pawel A. Osmulski, Maria E. Gaczynska 327-Pos B oard B261 ROLE OF MICROGLIA IN POLARIZATION GUIDED COLLECTIVE MIGRA- TION OF GLIOMAS - A BIOPHYSICAL APPROACH. Megha Jhunjhunwala , Yi-Hsuan Tsai, Chi-Shuo Chen

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