Biophysical Society 65th Annual Meeting Program Guide

707-Pos B oard B158 SYSTEMATIC MEASUREMENTS OF INTERLEAFLET FRICTION IN SUP- PORTED LIPID BILAYERS. Autumn A. Anthony , Aurelia R. Honerkamp- Smith 708-Pos B oard B159 STIFFENING TRANSITION IN ASYMMETRIC LIPID BILAYERS: THE ROLE OF HIGHLY-ORDERED DOMAINS AND THE EFFECT OF TEMPERATURE AND SIZE. Amirali Hossein , Markus Deserno 709-Pos B oard B160 CHALLENGING THE DOGMA - CELL PLASMA MEMBRANES ARE ASYMMETRIC NOT ONLY IN PHOSPHOLIPID COMPOSITION BUT ALSO ABUNDANCE. Milka Doktorova , Jessica L. Symons, Kandice R. Levental, Edward R. Lyman, Ilya Levental 710-Pos B oard B161 INTER- AND INTRA-PLANE INTERACTIONS CONTROL THE EXISTENCE OF MACRODOMAINS IN ASYMMETRIC GIANT UNILAMELLAR VESI- CLES. Thais A. Enoki , Haden L. Scott, Gerald W. Feigenson, Frederick A. B oard B162 CHICKEN-OR-EGG CONUNDRUM: ORDERING OF LIPIDS VS. CHOLES- TEROL LOCALIZATION IN THE ASYMMETRIC LIPID BILAYERS. Mohammadreza (Reza) Aghaaminiha (Amini) , Sumit Sharma 712-Pos B oard B163 DISTRIBUTION OF CHOLESTEROL IN ASYMMETRIC MEMBRANES DRIV- EN BY COMPOSITION AND DIFFERENTIAL STRESS. Malavika Varma , Markus Deserno 713-Pos B oard B164 PLASMALOGEN LIPIDS INFLUENCE LATERAL AND TRANSVERSE ORGA- NIZATION IN MODEL MEMBRANES. Haden L. Scott , Alison Leonard, Edward R. Lyman, Frederick A. Heberle 714-Pos B oard B165 ASYMMETRIC PHASE DIAGRAM OF A THREE COMPONENT MODEL MEMBRANE MIXTURE CONTAINING SPHINGOMYELIN: COUPLING OF LATERAL AND TRANSVERSE LIPID ORGANIZATION. Aaron Frederick , Frederick A. Heberle 715-Pos B oard B166 NANOSCALE CURVATURE OF NANOCELLULOSE PAPER PROMOTES HIGH YIELD SPONTANEOUS FORMATION OF GIANT VESICLES. Joseph Pazzi , Anand Subramaniam 716-Pos B oard B167 UNDERSTANDING THE YIELDS OF GIANT UNILAMELLAR VESICLES COM- POSED OF CHARGED MEMBRANES. Vaishnavi Girish 717-Pos B oard B168 BACTERIAL MIMETIC SYSTEMS FOR STUDYING BACTERIAL INACTIVA- TION AND INFECTION. Mareike Stephan , Stefanie Barbirz, Tom Robin- son, Naresh Yandrapalli, Rumiana Dimova Intracellular Calcium Channels and Calcium Sparks and Waves (Boards B169 - B180) 718-Pos B oard B169 HIGH-THROUGHPUT SCREENING AND DRUG DEVELOPMENT TO FIX RYR PATHOLOGY. Robyn T. Rebbeck , Kaja Rozman, Gabrielle M. Evans, Jacob Schwarz, Marzena Baran, Courtney C. Aldrich, Donald M. Bers, David D. Thomas, Razvan L. Cornea Heberle 711-Pos

719-Pos B oard B170 STRUCTURAL INSIGHTS INTO THE DIAMIDE MODULATION OF RYANODINE RECEPTOR. Ruifang Ma , Omid Haji-Ghassemi, Dan Ma, Heng Jiang, Lianyun Lin, Li Yao, Arthur Samurkas, Yuxin Li, Yiwen Wang, Shian Wu, Yan Zhang, Takashi Murayama, Bernard Moussian, Filip Van Petegem, Zhiguang Yuchi 720-Pos B oard B171 MODELING THE CROSSTALK BETWEEN RYANODINE AND IP3 RECEPTORS IN CARDIAC MYOCYTES. DeAnalisa C. Jones , Eric A. Sobie 721-Pos B oard B172 MITOCHONDRIAL CALCIUM UNIPORTER OVEREXPRESSION EXACERBATES ARRHYTHMOGENIC CALCIUMMISHANDLING IN DISEASED RAT VENTRICU- LAR MYOCYTES. Shanna Hamilton , Radmila Terentyeva, Fruzsina Perger, Dmitry A. Terentyev 722-Pos B oard B173 RYR1 AND RYR2 RESPOND DIFFERENTLY TO TOXICOLOGICALLY RELEVANT ETHANOL CONCENTRATIONS. Jerusalem Alleyne , Kelsey C. North, Yanping Ye, Anna N. Bukiya, Alex M. Dopico 723-Pos B oard B174 CRYSTAL STRUCTURES OF INSECT RYANODINE RECEPTOR DOMAINS. Lianyun Lin 724-Pos B oard B175 VISUALIZING UNRESOLVED SEGMENTS IN RYANODINE RECEPTOR CRYO-EM STRUCTURES. Bengt Svensson , David D. Thomas, Razvan L. Cornea 725-Pos B oard B176 A HOMOLOGY MODELLING STUDY OF POTENTIAL RYR2 STRUCTURAL CHANGES IN R2474S AND V2475F CPVT1. Jianshu Hu , Rebecca M. Sitsape- san, Maria Musgaard 726-Pos B oard B177 INCREASED SUBCELLULAR HETEROGENEITY IN CARDIAC MYOCYTES CAN LEAD TO ARRHYTHMIAS. Enes Haxhimali , Daisuke Sato 727-Pos B oard B178 DIFFERENTIAL SENSITIVITY TO HALOTHANE AMONG SUBGROUPS OF MALIGNANT HYPERTHERMIA SUSCEPTIBLE PATIENTS. INSIGHTS INTO DUAL PATHOPHYSIOLOGICAL MECHANISMS. Lourdes C. Figueroa , Natalia Kraeva, Carlo D. Manno, Sheila Riazi, Eduardo Rios 728-Pos B oard B179 POST-TRANSLATIONAL MODIFICATIONS PROMOTE FUNCTIONAL HETEROGE- NEITY IN CARDIAC MYOCYTES. Bardia Ghayoumi , Anna Fasoli, Christopher Y. Ko, Donald M. Bers, Daisuke Sato 729-Pos B oard B180 DEFECTIVE MITOCHONDRIA ELECTRON TRANSPORT CHAIN SUPERCOMPLEX ASSEMBLY UNDERLIES ABNORMAL CA 2+ RELEASE IN RAT MYOCYTES FROM HYPERTROPHIC HEARTS. Radmila Terentyeva , Shanna Hamilton, Fruzsina Perger, Wenzhuo Ma, Sandor Gyorke, Richard T. Clements, Dmitry A. Teren- tyev 730-Pos B oard B181 PUROMYCIN CAUSES PROTEIN UPTAKE BY CELLS FROM THE MEDIUM. Andrey O. Bogorodskiy , Ivan Maslov, Dmitry Burkatovsky, Alexey Mishin, Ivan Okhrimenko, Georg Bueldt, Joachim Altschmied, Judith Haendeler, Thomas Gensch, Valentin Borshchevskiy 731-Pos B oard B182 MODELING SELECTIVE TRAPPING OF WEAK-BASE LIGANDS IN ACIDIC INTRA- CELLULAR VESICLES. Philip Jordache , Benoit Roux, William N. Green, Esmael J. Haddadian Intracellular Transport (Boards B181 - B188)

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