Biophysical Society 65th Annual Meeting Program Guide

Voltage-gated Ca Channels (Boards B196 - B199)

732-Pos B oard B183 AN INTERACTION BETWEEN Β’-COP AND ITS ARFGAP, GLO3, IS RE- QUIRED TO MAINTAIN POST-GOLGI CARGO RECYCLING. Boyang Xie , Clara Guillem, Christian Jung, Amy K. Kendall, Jordan Best, Todd Gra- ham, Lauren P. Jackson 733-Pos B oard B184 PROBING BIOPHYSICAL PROPERTIES OF THE CYTOPLASM IN FISSION YEAST USING NANO-RHEOLOGY. Rikki M. Garner , Arthur T. Molines, Chenlei Hu, Joel Lemiere, Julie A. Theriot, Fred Chang 734-Pos B oard B185 DECTIN-1 MEDIATED DC-SIGN RECRUITMENT TO CANDIDA ALBICANS - CONTACT SITES. Rohan Choraghe , Aaron Neumann 735-Pos B oard B186 SIMULTANEOUS IMAGING OF DYNAMICS AND BIOCHEMICAL ACTIVITIES OF SINGLE PHAGOSOMES. Yanqi Yu , Zihan Zhang, Glenn F.W. Walpole, Yan Yu 736-Pos B oard B187 COMPUTATIONAL ACCOUNT OF THE FIRST STAGES IN THE ELEVATOR MOTION OF THE HUMAN EAAT3 GLUTAMATE TRANSPORTER. Ekaterina Kots , Harel Weinstein 737-Pos B oard B188 STICS ANALYSIS REVEALS THE ROLE OF TAU PHOSPHORYLATION IN REGULATING LYSOSOME TRANSPORT. Pamela Yaninska Voltage-gated Na Channels (Boards B189 - B195) 738-Pos B oard B189 ELIMINATING INDUCED POLARIZATION DRIVES CHANNEL TRANSITION FROM INSULATING TO CONDUCTING. H. Richard Leuchtag 739-Pos B oard B190 STRUCTURAL MODELING OF NA V -LIGAND INTERACTIONS WITH RO- SETTA’S GALIGANDDOCK. Brandon J. Harris , Phuong T. Nguyen, Vladimir Yarov-Yarovoy 740-Pos B oard B191 HETEROLOGOUS FUNCTIONAL EXPRESSION OF AN ASCIDIAN NAV1 CHANNEL WITH CLOSE RELATIONSHIP WITH ANCESTOR OF VERTEBRATE NEURONAL NAV CHANNELS. Yasushi Okamura , Takafumi Kawai, Masaki Hashimoto, Yuka Jinno, Måns Aspåker 741-Pos B oard B192 STRUCTURAL STUDIES OF THE INTERACTION BETWEEN THE PADDLE MOTIF FROM NA V 1.5DIV AND THE SEA ANEMONE TOXIN ANTHOPLEU- RIN-A. Adel K. Hussein , Mohammed H. Bhuiyan, Jianqin Zhuang, Boris Arshava, Sebastien F. Poget 742-Pos B oard B193 MARKOV AND EYRING MODELING PREDICT DIFFERENTIAL CONTRIBU- TIONS OF HOMOLOGOUS MUTATIONS IN HYPOKALEMIC PERIODIC PARALYSIS TO SKELETAL MUSCLE FIBER EXCITABILITY. James R. Groome , Landon Bayless-Edwards, Lance Port, Frank Lehmann-Horn, Karin Jurkat- Rott 743-Pos B oard B194 TARGETING THE VASCULAR ENDOTHELIAL BARRIER TO PREVENT NANOSCALE CARDIAC REMODELING: A NOVEL STRATEGY TO PREVENT ATRIAL FIBRILLATION. Louisa Mezache , Amara Greer-Short, Przemyslaw Radwanski, Thomas J. Hund, Rengasayee Veeraraghavan 744-Pos B oard B195 COMPUTATIONAL STUDY OF ION SELECTIVITY IN EUKARYOTIC VOLTAGE- GATED SODIUM CHANNELS. Boris S. Zhorov

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745-Pos B oard B196 NIFEDIPINE MODULATES THE ACTIVATION OF CA V 1.1 VOLTAGE-SENSING DOMAINS. Marina Angelini , Nicoletta Savalli, Federica Steccanella, Ric- cardo Olcese 746-Pos B oard B197 VOLTAGE SENSOR OPERATION IN THE EMBRYONIC SPLICE VARIANT OF SKELETAL CA V 1.1 CHANNELS. Nicoletta Savalli , Marina Angelini, Federica Steccanella, Alan Neely, Riccardo Olcese 747-Pos B oard B198 DISSECTING THE ROLE OF CA V 1.2 DYSFUNCTION IN THE PATHOGENESIS OF AUTISM SPECTRUM DISORDER. Kevin G. Herold , Moradeke A. Bamg- boye, Deborah DiSilvestre, John Hussey, Josiah O. owoyemi, Andrea Meredith, Ivy E. Dick 748-Pos B oard B199 ASSESSING THE IMPACT OF CALMODULINOPATHIC MUTATIONS ON NEURONAL ION CHANNEL REGULATION. John W. Hussey , Emily De- Marco, Deborah DiSilvestre, Helene H. Jensen, Mette Nyegaard, Michael T. Overgaard, Ivy E. Dick Ion Channel Regulatory Mechanisms (Boards B200 - B220) 749-Pos B oard B200 REGULATION OF THE ACTIVITY OF MITOCHONDRIAL LARGE-CONDUC- TANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL THROUGH A NEW EXTERNAL HEME-BINDING SITE. Agnieszka Walewska , Piotr Koprowski, AdamM. Szewczyk 750-Pos B oard B201 ASSESSING THE ROLE OF ELECTROSTATIC INTERACTIONS IN THE MECHA- NISM OF BETA-BARREL CHANNEL GATING. Deborah Aurora Perini, Antonio Alcaraz, Vicente M. Aguilella, Maria Queralt-Martin 751-Pos B oard B202 ELUCIDATING THE STRUCTURAL CONSTITUENTS OF FIBROBLAST GROWTH FACTOR 14 THAT CONFER ITS MODULATORY EFFECTS ON THE VOLTAGE-GATED SODIUM CHANNEL 1.6. Nolan M. Dvorak , Paul Wad- sworth, Pingyuan Wang, Haiying Chen, Jia Zhou, Fernanda Laezza 752-Pos B oard B203 IDENTIFICATION OF GATING SENSITIVE RESIDUES IN TREK-2. Chun Kei Lam , Bert L. de Groot 753-Pos B oard B204 PATHWAYS FOR QUATERNARYAMMONIUM BLOCKER ENTRY INTO CLOSED CALCIUM ACTIVATED POTASSIUM CHANNELS. Chen Fan , Emelie Flood, Nattakan Sukomon, Toby W. Allen, Crina M. Nimigean 754-Pos B oard B205 CHARACTERIZATION OF ION TRANSPORT BASED ON CONDUCTANCE VERSUS CONCENTRATION CURVES. A THEORETICAL ANALYSIS. Suren A. B oard B206 IN SITU, LABEL-FREE STUDY OF THE CORRELATION BETWEEN MG2+ UPTAKE PROTEINS AND MOTILITY OF SALMONELLA TYPHIMURIUM US- ING TIME-RESOLVED DYNAMIC LASER SPECKLE IMAGING. Keren Zhou, Cassandra N. Nunez , Varasiddhi J. Govindraj, Aida Ebrahimi 756-Pos B oard B207 CONDUCTANCE MECHANISM OF MUTANT K + CHANNELS. Andrei Mironenko , Bert L. de Groot, Wojciech Kopec Tatulian 755-Pos

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