Biophysical Society 65th Annual Meeting Program Guide

Actin Structure, Dynamics, and Associated Proteins (Boards B221 - B233) 770-Pos B oard B221 APPLICATION OF FLORY-STOCKMAYER THEORY TO ACTOMYOSIN NETWORKS REVEALS MULTIPLE CONNECTIVITY STATES THAT GIVE RISE TO DISTINCT BEHAVIORS OF THE NETWORK. Carlos A. Bueno Basurco , James Liman, Nicholas P. Schafer, Margaret S. Cheung, Peter G. Wolynes 771-Pos B oard B222 INSIGHTS FROM GRAPH THEORY ON THE MORPHOLOGIES OF ACTO- MYOSIN NETWORKS WITH MULTILINKERS. Yossi Eliaz, Francois Nedelec, Gregory Morrison, Herbert Levine, Margaret S. Cheung 772-Pos B oard B223 SIMULATING THE ARCHITECTURE OF THE ACTIN CORTEX DURING BLEB NUCLEATION. Calvin Calvin Pozderac, Joshua Riber, Wanda Strychalski 773-Pos B oard B224 COUNTERACTIVE EFFECTS OF ELECTROSTATICS AND MACROMOLECULAR CROWDING ON ACTIN BUNDLE MECHANICS AND SECONDARY STRUC- TURE. Nicholas Castaneda , Briana Lee, Jinho Park, Laurene Tetard, Ellen B oard B225 CROWDING TUNES THE ORGANIZATION AND MECHANICS OF ACTIN BUNDLES INDUCED BY ACTIN CROSSLINKING PROTEINS. Jinho Park , Myeongsang Lee, Briana Lee, Nicholas Castaneda, Laurene Tetard, Ellen B oard B226 THE THREE-DIMENSIONAL MODEL OF THE TROPOMODULIN ASSEMBLY AT THE POINTED END OF ACTIN FILAMENT. Balaganesh Kuruba , Garry E. Smith, Dmitri Tolkatchev, Alla S. Kostyukova 776-Pos B oard B227 ACTIN TURNOVER REGULATION THROUGH MYOSIN ACTIVITY AND NET- WORK ARCHITECTURE. Danielle R. Scheff , Margaret L. Gardel 777-Pos B oard B228 INTERDEPENDENCE OF FILAMENT NUCLEATION, ELONGATION AND CROSSLINKING IN ACTIN BUNDLE ASSEMBLY. Laura A. Sherer , Naomi Courtemanche 778-Pos B oard B229 CALPONIN 2 REGULATES THE RATE OF CYTOKINESIS. Tzu-Bou Hsieh , Airong Qian, Md Moazzem Hossain, Jian-Ping Jin 779-Pos B oard B230 MOLECULAR MECHANISM OF LEIOMODIN ACTING AS A LEAKY CAP AT THE POINTED END OF THIN FILAMENTS. Garry E. Smith , Dmitri Tolk- atchev, Alla S. Kostyukova 780-Pos B oard B231 EXPLORING THE IMPACT OF ARP2/3 CONCENTRATION ON ACTOMYOSIN DYNAMICS. Chengxuan Li , James Liman, Yossi Eliaz, Margaret S. Cheung 781-Pos B oard B232 REGULATION OF ACTIN FILAMENT ELONGATION BY A FORMIN-PROFILIN CHIMERA. Mark E. Zweifel, Naomi Courtemanche 782-Pos B oard B233 STUDYING THE LOCAL YOUNG’S MODULUS OF PC-3 CELLS VIA SCAN- NING ION-CONDUCTANCE MICROSCOPY. Vasilii Kolmogorov , Alexander Vaneev, Yuri M. Efremov, Nikita Savin, Aleksei Iakovlev, Anna Alova, Svet- lana Lavrushkina, Alexander Erofeev, Petr Gorelkin, Natalia Klyachko, Igor Kireev, Alexander Majouga, Pavel Novak, Yuri E. Korchev H. Kang 774-Pos H. Kang 775-Pos

757-Pos B oard B208 THE PH MODULATION OF THE VOLTAGE SENSOR IN THE VOLTAGE-GATED PROTON CHANNEL (H V 1). Emerson M. Carmona , Osvaldo Alvarez, Alan Neely, Peter H. Larsson, Jose-Antonio Garate, Miguel Fernandez, Ramon Latorre, Carlos L. Gonzalez 758-Pos B oard B209 MODELLING WATER BEHAVIOUR IN HYDROPHOBIC GATES OF ION CHAN- NELS. Charlotte I. Lynch , Shanlin Rao, Gianni Klesse, Stephen J. Tucker, Mark S.P. Sansom 759-Pos B oard B210 LIPID-PROTEIN INTERACTIONS MODULATE THE CONFORMATIONAL EQUI- LIBRIUM OF A POTASSIUM CHANNEL. Ruo-Xu Gu , Bert L. de Groot 760-Pos B oard B211 INTERMOLECULAR COOPERATIVE GATING IN PIEZO1 CHANNELS. Tharaka D. Wijerathne , Alper D. Ozkan, Jerome J. Lacroix 761-Pos B oard B212 MAPPING THE CONFORMATIONAL STATES OF THE OUTER VESTIBULE OF KCSA, A PROKARYOTE POTASSIUM CHANNEL, USING THE LONG CHAIN QUATERNARY AMMONIUM BLOCKER, TETRAOCTYLAMMONIUM. Clara Díaz-García , Maria Lourdes Renart, Ana Marcela Giudici, Jose Anto- nio Poveda, Aleksander Fedorov, Jose M. Gonzalez-Ros, Mário Nuno Berberan-Santos, Manuel Prieto, Ana Coutinho 762-Pos B oard B213 BREAKING THE DIMER OF THE VOLTAGE SENSING PHOSPHATASE. Joshua A. Davisson , Vamseedhar Rayaprolu, William J. Ratzan, John Kelley, Guil- laume Sandoz, Susy C. Kohout 763-Pos B oard B214 MOLECULAR MECHANISM OF HERG1 CHANNEL REGULATION BY CERAMIDES. Williams E. Miranda , Jiqing Guo, Haydee Mesa Galloso, Valentina Corradi, Peter D. Tieleman, Henry J. Duff, Sergei Y. Noskov 764-Pos B oard B215 STRUCTURES OF A CONSTITUTIVELY ACTIVE MUTANT OF THE CALCIUM- ACTIVATED CHLORIDE CHANNEL TMEM16A IN LIGAND-FREE AND -BOUND STATES. Andy K.M. Lam , Jan Rheinberger, Cristina Paulino, Raimund Dutzler 765-Pos B oard B216 ACTIVATION OF TWO DISTINCT POTASSIUM CURRENTS IN MELANOMA CELLS BY OXIDATION. Loretta Ferrera, Raffaella Barbieri, Cristiana Picco, Paolo Zuccolini, Giovanni Zifarelli, Alessia Remigante, Maria Rita Fuma- galli, Caterina La Porta, Paola Gavazzo, Michael Pusch 766-Pos B oard B217 MAGNETOGENETICS: THE DEBATE IS ON. Gerardo Abbandonato , Lorenzo Brocca, Federica Gasparri, Matteo Giannangeli, Caterina Ricci, Ales- sandro Caselli, Laura Cantù, Elena Del Favero, Alberto Boffi, Alessandra Bonamore, Alessandro Podestà, Gerhard Thiel, Anna Moroni 767-Pos B oard B218 THE ION PERMEATION AND SELECTIVITY MECHANISMS OF RYANODINE RECEPTORS - MOLECULAR DYNAMICS STUDY WITH A NEWMULTI-SITE CA 2+ MODEL. Chunhong Liu , Aihua Zhang, Hua Yu, Chen Song 768-Pos B oard B219 REGULATION OF LOW VOLTAGE-ACTIVATED CALCIUM CHANNELS BY NEDD4 FAMILY OF E3 UBIQUITIN LIGASES. Arden Darko-Boateng , Henry M. Colecraft 769-Pos B oard B220 A SCREENING STRATEGY TO IMPROVE SURFACE EXPRESSION OF THE SYN- THETIC CHANNEL BLINK IN MAMMALIAN CELLS. Lorenzo Brocca , Shadi Hambo, Anna Moroni

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