Biophysical Society 65th Annual Meeting Program Guide

Platform Membrane Protein Dynamics and Folding I 10:00 am - 11:30 am Chair Dirk Slotboom, University of Groningen, The Netherlands No Abstract 10:00 am MEMBRANE-ASSISTED DOMAIN MOVEMENTS IN SOLUTE TRANSPORT- ERS. Dirk Slotboom 919-Plat 10:30 am TEMPERATURE DEPENDENCY OF CLC-EC1 DIMERIZATION IN LIPID BILAY- ERS. Rahul Chadda , Taeho Lee, Priyanka Sandal, Robyn Mahoney-Krusz- ka, Janice L. Robertson 920-Plat 10:45 am REGULATING THE MEMBRANE TRANSPORT PROCESSES FOR BIO-MOL- ECULES VIA AN ENGINEERED AEROLYSIN. Meng-Yin Li , Xue-yuan Wu, Yi-Lun Ying, Yi-Tao Long 921-Plat 11:00 am DEVELOPING A COARSE-GRAINED MODEL FOR SECRETION OF THE PAS- SENGER DOMAIN OF THE AUTOTRANSPORTER ESPP TO REACH REALISTIC SIMULATION TIME SCALES. Lixinhao Yang , Jinchan Liu, James C. Gumbart 922-Plat 11:15 am THE INTERPLAY BETWEEN THE SELF-ORGANIZATION AND CURVATURE SENSING IN SEPTIN ASSEMBLIES. Ehssan Nazockdast, Wenzheng Shi , Kevin Cannon, Amy Gladfelter Platform Membrane Peptides, Fusion, and Non-Bilayers 10:00 am - 11:30 am Chair Pedro Carvalho, University of Oxford, United Kingdom 923-Plat 10:00 am STRUCTURE OF THE YEAST SEIPIN REVEALS DETERMINANTS FOR LIPID DROPLET BIOGENESIS. Pedro Carvalho , Yoel Klug, Justin Deme, Susan Lea 924-Plat 10:30 am BINDING MODE OF SARS-COV2 FUSION PEPTIDE TO HUMAN CELLULAR MEMBRANES. Defne Gorgun , Muyun Lihan, Karan Kapoor, Emad Tajk- horshid 925-Plat 10:45 am DESCRIBING ANTIFUNGAL DRUG -STEROL INTERACTIONS INSIDE THE MEMBRANE: THE ROLE OF DYNAMICS. Kevin J. Cheng , Ashley M. De Lio, Agnieszka Lewandowska, Corinne P. Soutar, Martin D. Burke, Chad M. Rienstra, Taras V. Pogorelov 926-Plat 11:00 am EBOLA VIRUS GLYCOPROTEIN INTERACTS WITH CHOLESTEROL TO ENHANCE MEMBRANE FUSION AND CELL ENTRY. Jinwoo Lee, Alex J.B. Kreutzberger, Laura Odongo , Elizabeth A. Nelson, David Nyenhuis, Volker Kiessling, Binyong Liang, David S. Cafiso, Judith M. White, Lukas K. Tamm 927-Plat 11:15 am NANOMECHANICAL CHARACTERIZATION OF THE SYNERGISM OF ANTIMI- CROBIAL PEPTIDES PGLA AND MAG2 FOR LIPID MEMBRANE DISRUPTION. Fabio Perissinotto, Sebastien Janel, Javier Lopez-Alonso, Vincent Dupres, Burkhard Bechinger, Frank Lafont, Lorena Redondo-Morata

Thursday, February 25

T H U R S D A Y

General Networking 9:00 am-10:00 am

Catch up with colleagues and friends in the biophysical community during our networking hour. This event, which is open to all meeting attendees, provides meet-and-greet opportunities to enhance your virtual meeting experience. Symposium New and Notable 10:00 am - 11:30 am Co-chairs Patricia Bassereau, Institut Curie, France Bertrand Garcia-Moreno, Johns Hopkins University, USA No Abstract 10:00 am PHOTOBIOLOGY OF NEWMICROBIAL RHODOPSINS. Keiichi Inoue No Abstract 10:22 am A MEMBRANE ASSOCIATED ACTIN-SPECTRIN PERIODIC LATTICE ACTS AS A SHOCK ABSORBER TO PROTECT AXONS UNDER MECHANICAL STRESS. Pramod Pullarkat No Abstract 10:44 am STRUCTURAL BASIS OF WNT SECRETION BY ITS CARRIER. Rie Nygaard No Abstract 11:06 am LIFE OF VIMENTIN INTERMEDIATE FILAMENTS INSIDE AND OUTSIDE THE CELL. Alison Patteson Platform Protein Dynamics and Allostery II 10:00 am - 11:30 am Chair Faruck Morcos, The University of Texas at Dallas, USA 914-Plat 10:00 am EVOLUTIONARY DETERMINED EPISTASIS ADVANCES CONFORMATIONAL SAMPLING, MOLECULAR DESIGN AND EVOLUTIONARY MODELS. Faruck Morcos 915-Plat 10:30 am INVESTIGATION OF ALLOSTERIC MECHANISM FROM AN EVOLUTION- ARY PERSPECTIVE. Riya Samanta , Calvin Muth, Neel Sanghvi, Dorothy Beckett, Silvina Matysiak 916-Plat 10:45 am UREA AS A PROTEIN LID OPENER: OVERCOMING SUBSTRATE INHIBITION IN ADENYLATE KINASE BY TUNING CONFORMATIONAL DYNAMICS. David Scheerer , Haim Yuval Aviram, HishamMazal, Inbal Riven, Gilad Haran 917-Plat 11:00 am REFINING PROTEIN CONFORMATIONAL ENSEMBLES FROM SEPARATE EXPERIMENTAL MEASUREMENTS. Emily Boland , Jennifer M. Hays, Peter Kasson 918-Plat 11:15 am ALLOSTERIC COMMUNICATION IN PDZ3 IS ORCHESTRATED BY THE CHARGED N-TERMINUS. Tandac Furkan Guclu , Nazli Kocatug, Canan Atilgan, Ali Rana Atilgan

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