Biophysical Society 65th Annual Meeting Program Guide

1033-Pos B oard B83 DYNAMICAL HETEROGENEITY IN THE MEASLES VIRUS IDP N TAIL IN ITS FREE AND BOUND STATES. John Kunkel , Gerdenis Kodis, Gabor Nagy, Christophe Bignon, Sonia Longhi, Andrea C. Vaiana, Helmut Grubmuller, Wenwei Zheng, Sara M. Vaiana 1034-Pos B oard B84 REENTRANT PHASE TRANSITION AND OUT-OF-EQUILIBRIUM BEHAVIOR OF LIQUID POLYPHOSPHATE CONDENSATE. Hannah M. Seppala , Priya R. B oard B85 SEQUENCE AND CHEMICAL ENVIRONMENT DETERMINE THE GLOBAL DIMENSION OF INTRINSICALLY DISORDERED PROTEIN ENSEMBLES. Feng Yu , David Moses, Alex S. Holehouse, Shahar Sukenik 1036-Pos B oard B86 SOLVENT RELAXATION SIGNIFICANTLY CONTRIBUTES TO ELECTRON TRANSFER RATES BETWEEN TRYPTOPHAN TRIPLET STATE AND CYS- TINE. Gerdenis Kodis, John D. Kunkel, Wenwei Zheng, Dmitry V. Maty- ushov, Sara M. Vaiana 1037-Pos B oard B87 HOW DO LIGANDS TUNE THE ASSEMBLY AND DISSOLUTION OF BIOMO- LECULAR CONDENSATES? Kiersten M. Ruff , Furqan Dar, Rohit V. Pappu 1038-Pos B oard B88 MODELING CHROMATIN CONDENSATION WITH COARSE-GRAINED MOD- ELS. Kathryn M. Lebold , Robert B. Best 1039-Pos B oard B89 INVESTIGATING THE ROLE OF THE INTRINSICALLY DISORDERED TRANSAC- TIVATION DOMAIN OF NF-KAPPAB IN DNA BINDING AND CO-ACTIVATOR INTERACTIONS. Hannah E.R. Baughman , Amalia C. Villagran-Suarez, Francis X. Alipranti, Dominic Narang, Elizabeth A. Komives 1040-Pos B oard B90 TOWARD EFFICIENT Q -CANONICAL MONTE CARLO SIMULATIONS OF THE IMPACT OF CHARGE REGULATION ON CONFORMATIONAL ENSEMBLES OF INTRINSICALLY DISORDERED PROTEINS. Martin J. Fossat , Rohit V. Pappu 1041-Pos B oard B91 SEQUENCE-DEPENDENT VISCOELASTICITY OF BIOMOLECULAR CONDEN- SATES. Ibraheem Alshareedah , Priya R. Banerjee 1042-Pos B oard B92 MODELLING THE MULTIFARIOUS CONFORMATIONS OF THE INTRINSI- CALLY DISORDERED PROTEIN 4E-BP2 WITH SM-FRET, SAXS & PRE RE- STRAINTS. Spencer Smyth , Thomas Tsangaris, Alaji Bah, Julie D. Forman- Kay, Claudiu C. Gradinaru 1043-Pos B oard B93 A Β(1-42) OLIGOMER INDUCED PERFORATION OF MEMBRANES REVEALS A MECHANISM FOR NEUROTOXICITY AND NEWMODES OF DRUG TARGETING. Andres S. Arango , Soumyo Sen, Moeen Meigooni, Emad Tajkhorshid 1044-Pos B oard B94 NOVEL DISEASE VARIANTS REVEAL CRITICAL FUNCTIONS FOR INTRIN- SICALLY DISORDERED REGIONS ENCODED BY THE DIABETES GENE CLEC16A . Morgan Gingerich 1045-Pos B oard B95 A HYDRODYNAMIC INSTABILITY DRIVES PROTEIN DROPLET FORMATION ON MICROTUBULES TO NUCLEATE BRANCHES. Bernardo Gouveia , Sagar U. Setru, Ray Alfaro-Aco, Joshua W. Shaevitz, Howard A. Stone, Sabine Petry Banerjee 1035-Pos

1046-Pos B oard B96 ALLOSTERIC REGULATION OF NUCLEOPORIN ASSEMBLIES BY PROTEIN INTRINSIC DISORDER. Bartlomiej J. Blus , Aleksandra Krolak, Junseock Koh, Hyuk-Soo Seo, Elias Coutavas 1047-Pos B oard B97 COMPREHENSIVE ANALYSIS OF INTRINSICALLY DISORDERED REGIONS TO ELUCIDATE THEIR PHYSICAL PROPERTIES USING A MODIFIED PARAM- ETER. Hayato Aida , Ryuhei Harada, Yasuteru Shigeta, Kentaro Tomii 1048-Pos B oard B98 SHINING LIGHT ON THE ‘DARK MATTER’ OF THE NUCLEAR PORE COM- PLEX. Miao Yu , Sofya Mikhaleva, Piau Siong Tan, Christopher D. Reinke- meier, Edward A. Lemke 1049-Pos B oard B99 MEMBRANE CHOLESTEROL REGULATES THE BINDING OF ALPHA- SYNUCLEIN TO SYNAPTIC VESICLES, AND ITS SUBSEQUENT FUNCTIONAL AND PATHOGENIC BEHAVIOR. Anindita Mahapatra , NarattamMandal, Krishnananda Chattopadhyay Ribosomes and Translation (Boards B100 - B106) 1050-Pos B oard B100 SINGLE-MOLECULE DYNAMICS OF EIF4F-MEDIATED MRNA RECOGNI- TION. Burak Cetin , Gary Song, Seán E. O’Leary 1051-Pos B oard B101 A CONSERVED ARGININE IN SWITCH I IS CRITICAL FOR PPGPP BIND- ING TO THE PROKARYOTIC TRANSLATIONAL GTPASE BIPA. Victoria L. Robinson , Gilman Dionne, Kevin J. Boyd, Ala M. Shaqra, Heidi Erlandsen, Madhubrata Ghosh, Ganesh S. Anand, Eric R. May 1052-Pos B oard B102 ELONGATION FACTOR G MUTATIONS AND BACTERIAL RESISTANCE TO AMINOGLYCOSIDES. Sara Gabrielli , Lars V. Bock, Helmut Grubmueller 1053-Pos B oard B103 ELUCIDATING THE MECHANISM OF EUKARYOTIC POLYPEPTIDE ELONGA- TION BY SINGLE-MOLECULE FRET. Clark Fritsch , Arpan Bhattacharya, Martin Ng, Hong Li, Barry S. Cooperman, Yale E. Goldman 1054-Pos B oard B104 MECHANISM OF THE ACTIVATION OF RIBOSOME RESCUE FACTOR ARFB. Lars V. Bock 1055-Pos B oard B105 ELECTROSTATIC INTERACTIONS BETWEEN NASCENT CHAINS AND THE RIBOSOME EXIT TUNNEL GENERATE FORCES THAT MODIFY TRANSLATION RATES. Sarah E. Leininger , Judith Rodriguez, Quyen Vu, Yang Jiang, Mai S. Li, Edward P. O’Brien 1056-Pos B oard B106 LIVE-CELL SINGLE-MOLECULE TRACKING OF THE TRANSLATION MACHIN- ERY. Ivan L. Volkov , Mikhail Metelev, Erik Lundin, Javier Aguirre, Magnus Johansson DNA Structure and Dynamics (Boards B107 - B132) 1057-Pos B oard B107 HIGH-COVERAGE NUCLEIC ACID PROBES FOR DISTINGUISHING SARS- COV-2 FROM INFLUENZA. Samantha J. Courtney , Zachary R. Stromberg, James Theiler, Brian T. Foley, Jason D. Gans, Karina Yusim, Jessica Z. Kubicek-Sutherland

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