Biophysical Society 66th Annual Meeting Program Guide

900-Pos Board B41 MONITORING PROTEIN UNFOLDING AND DNA BINDING USING PROTEIN CHARGE TRANSFER SPECTRA. Anurag Priyadarshi , Rajaram Swaminathan 901-Pos Board B42 THREADING PROTEINS AT THE SPEED LIMIT OF FOLDING. Prabhat Tripathi , Arash Firouzbakht, Martin Gruebele, Meni Wanunu 902-Pos Board B43 SINGLE-MOLECULE DISSECTION OF COUPLING MECHANISMS BETWEEN COFACTOR BINDING AND FOLDING OF A COMPLEX PROTEIN. Sahar Foroutannejad, Lydia Good, Craig Manahan, Zachariah Ingram, Changfan Lin, Mahlet Tadesse, Aaron L. Lucius, Brian R. Crane, Rodrigo A. Maillard 903-Pos Board B44 INTERFACING PROTEIN FOLDING INTERMEDIATES VIA CONTROLLED RANDOMNESS. Zhiyuan Ruan 904-Pos Board B45 FOLDING ENERGY LANDSCAPE OF INITIATOR CASPASES. Mithun Nag Karadi Giridhar 905-Pos Board B46 TUNING SOLVENT ELECTROSTATIC ENVIRONMENT OF AMIDE CARBONYLS AS PROTOTYPICAL PEPTIDE BACKBONES. Steven D.E. Fried , Chu Zheng, Yuezhi Mao, Thomas E. Markland, Steven G. Boxer 906-Pos Board B47 VALIDATING ACTION-CSA APPROACH FOR FINDING MULTIPLE PROTEIN FOLDING PATHWAYS. Jiyeon Min , Mahdi Ghorbani, Juyong Lee, Bernard R. Brooks 907-Pos Board B48 QUANTUMMECHANICAL EFFECTS IN PROTEIN OSCILLATIONS. Garrett Baughman , Hunter S. Baker, Preet Sharma 908-Pos Board B49 THE DIMENSIONS OF AN ENSEMBLE OF COLLAPSED DISORDERED PRO - TEIN MOLECULES UNDER FOLDING CONDITIONS. Elisha Haas , Dan Amir, Osman Bilsel Protein-Small Molecule Interactions II (Boards B50 - B74) 909-Pos Board B50 BINDING MECHANISMS OF THE TARANTULA VENOM PROTX-II TO THE HUMAN NAV1.7 CHANNEL. Khoa Ngo , Diego Lopez Mateos, Yanxiao Han, Vladimir Yarov-Yarovoy, Igor Vorobyov, Colleen E. Clancy 910-Pos Board B51 MOLECULAR DYNAMICS SIMULATIONS REVEAL THAT ACETYLATION OF CATALYTIC LYSINE BALANCES ENTHALPIC DESTABILIZATION WITH ENTRO - PIC STABILIZATION TO PRESERVE ATP BINDING AFFINITIES IN CDK1. Krishna K. Vishwakarma , Ullas K. Seetharaman, Ravindra Venkatramani 911-Pos Board B52 COMPUTER SIMULATIONS OF PIEZO1 CHANNEL REGULATION BY MEM - BRANE AND SMALL MOLECULE. Yun Lyna Luo , Wenjuan Jiang, YiChun Lin, Han Zhang, Wesley M. Botello-Smith 912-Pos Board B53 MECHANISM OF LIGAND BINDING PATHWAYS AND ACTIVATION OF THE SUCCINATE RECEPTOR. Aslihan Shenol Iliyaz 913-Pos Board B54 HIGH-RESOLUTION MODELING OF SMALL MOLECULE - ION CHANNEL INTERACTIONS WITH ROSETTA’S GALIGANDDOCK. Brandon J. Harris , Phuong T. Nguyen, Vladimir Yarov-Yarovoy

887 -Pos Board B28 SPECTROSCOPIC ANALYSIS OF METAL IONS EFFECT ON THE AGGREGA - TION OF A Λ6AJL2R24G PROTEIN VARIANT. Fernanda Mata , Lina A. Rivillas-Acevedo 888 -Pos Board B29 Travel Award Winner RESONANCE ASSIGNMENTS TOWARD SOLUTION-STATE NMR STRUCTURE DETERMINATION OF NOVEL BOX JELLYFISH PROTEIN. Jessica I. Kelz , Mina Mozafari, Domarin Khago, Megha H. Unhelkar, Brenna Norton-Baker, Megan A. Rocha, Rachel W. Martin 889-Pos Board B30 SPR AND HDXMS ANALYSIS OF INTERACTIONS BETWEEN THROMBO - MODULIN DOMAIN 1 AND COMPLEMENT PROTEINS. Julia R. Koeppe , Jose Giler, Timothy Bodah, Kevin Farrell, Chelsea Gomez, Michael Scott 890-Pos Board B31 INVESTIGATING THE PROTEIN CONFORMATIONAL LANDSCAPE ASSOCI - ATED WITH COGNITIVE DECLINE IN AGING WITH MASS SPECTROME - TRY. Haley E. Tarbox , Audrey Branch, Michela Gallagher, Stephen D. Fried Protein Stability, Folding, and Chaperones I (Boards B32 - B49) 891-Pos Board B32 MONITORING PROTEIN FOLDING ON AND OFF THE RIBOSOME USING STRUCTURAL MASS SPECTROMETRY APPROACHES. Shawn M. Costello , Natalie R. Dall, Sayan Gupta, Corie Y. Ralston, Susan Marqusee 892-Pos Board B33 Travel Award Winner THE CLPX TRANSLOCASE AND ITS APPLICATION TO THE STUDY OF VECTO - RIAL PROTEIN FOLDING IN VITRO. Iker F. Soto Santarriaga , Patricia L. Clark 893-Pos Board B34 Travel Award Winner CRITICAL BEGINNINGS: TUNING OF SOLUBILITY AND STRUCTURAL AC - CURACY OF NEWLY-SYNTHESIZED PROTEINS BY THE HSP70 CHAPERONE SYSTEM. Rachel B. Hutchinson , Rayna M. Addabbo, Matthew D. Dalphin, Miranda F. Mecha, Yue Liu, Silvia Cavagnero 894-Pos Board B35 Travel Award Winner STUDYING THE REFOLDABILITY OF THE PROTEOME USING CROSSLINKING MASS SPECTROMETRY. Yingzi Xia , Stephen D. Fried 895-Pos Board B36 EXPLORING KINETICALLY CONTROLLED PROTEIN SOLUBILITY UNDER PHYSIOLOGICALLY RELEVANT CONDITIONS. Hung H. Dang , Lucas Bartel, Kevin A. England, Silvia Cavagnero 896-Pos Board B37 TRAMPLE: MAXIMUM LIKELIHOOD ESTIMATION OF PROTEIN UNFOLDING RATES FROM ALL-ATOM TEMPERATURE RAMP SIMULATIONS. Michael V. LeVine , Stefano Piana-Agostinetti, Tamas Szalay, David E. Shaw 897-Pos Board B38 PROBING UNFOLDING BARRIERS IN HIGH THROUGHPUT. Miriam R. Hood , Eva Gerber, Susan Marqusee 898-Pos Board B39 ASSESSING EXTREMOPHILIC PROTEOME REFOLDABILITY WITH MASS SPECTROMETRY. Haley M. Moran , Stephen D. Fried 899-Pos Board B40 Travel Award Winner PEGYLATION OF THE GALECTIN-3 CARBOHYDRATE RECOGNITION DOMAIN CREATES A KINETIC TRAP PROTECTING THE PROTEIN FROM THERMAL UNFOLDING. Amanda Pritzlaff, Guillaume Ferré , Emma Mulry, Michael Harris, Matthew T. Eddy

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