Biophysical Society 66th Annual Meeting Program Guide

2039-Pos Board B497 TUMOR TARGETED MESOPOROUS SILICA NANOPARTICLES FUNCTION - ALIZED WITH PROGRAMMED DEATH RECEPTOR LIGAND-1 ANTIBODY (ANTI-PD-L1) FOR COMBINED CHEMO- AND IMMUNOTHERAPY. Palanikumar Loganathan , Mazin Magzoub 2040-Pos Board B498 PHOTOCONTROL OF SMALL GTPASE RAS GTPASE CYCLE USING PHO - TOCHROMIC MOLECULE. Yuichi Imamura , Nobuyuki Nishibe, Kazunori Kondo, Shinsaku Maruta 2041-Pos Board B499 ORTHOGONAL CONTROL OF DNA NANOSWITCHES WITH MIXED PHYSI - CAL AND BIOCHEMICAL CUES. Nathan T. Forrest , Javier Vilcapoma, Kristina Alejos, Ken Halvorsen, Arun Richard Chandrasekaran 2042-Pos Board B500 GLOBAL MOLECULAR FEATURES OF G PROTEIN COUPLED RECEPTORS CONFORMATION REVEALED BY MACHINE LEARNING. Parisa Mollaei , Prakarsh Yadav, Yuyang Wang, Zhonglin Cao, Amir Barati Farimani 2043-Pos Board B501 COMPUTATIONALLY ENGINEERED ACE2 DECOY BINDS WITH NANOMO - LAR AFFINITY WITH THE SARS-COV-2 SPIKE PROTEIN. Mohammad S. Islam , Brandon Havranek, Erik Procko, Kui Chan 2044-Pos Board B502 USING DEEP MUTATIONAL SCANNING TO IDENTIFY THE DETERMINANTS OF ANTIBIOTIC RESISTANCE. Christian B. Macdonald , Alexis Kelley, Jenna Pellegrino, Willow Coyote-Maestas, James Fraser 2045-Pos Board B503 POLYVALENT GUIDE RNAS FOR CRISPR ANTIVIRALS. Rammyani Bagchi, Rachel Tinker-Kulberg, Mohammad Salehin, Tinku Supakar, Sydney Chamberlain, Ayalew Ligaba-Osena, Eric A. Josephs 2046-Pos Board B504 ENHANCING THE BIOSTABILITY OF NUCLEIC ACID NANOSTRUC - TURES. Arun Richard Chandrasekaran 2047-Pos Board B505 CONTROLLED LASER-INDUCED FABRICATION OF MULTICHANNEL SOLID-STATE NANOPORE SENSORS FOR STUDYING SINGLE-MOLECULE PROTEIN DYNAMICS. Amr K. Makhamreh , Ali Fallahi, Hirohito Yamazaki, Meni Wanunu 2048-Pos Board B506 RADIOFREQUENCY DIELECTRIC PROPERTIES OF STANDARD LIQUIDS: WATER, METHANOL AND ETHANOL. Christopher E. Bassey 2049-Pos Board B507 RAPID IDENTIFICATION OF DNA FRAGMENTS THROUGH DIRECT SE - QUENCING WITH ELECTRO-OPTICAL ZERO-MODE WAVEGUIDES. Fatemeh Farhangdoust , Mohammad A. Alibakhshi, Meni Wanunu 2050-Pos Board B508 SINGLE-MOLECULE INVESTIGATION OF PRODUCT INHIBITION OF CEL7 CELLULASE ACTIVITY BY CELLOBIOSE. Daguan Nong , Zachary K. Haviland, Mikaela Mayers, Ming Tien, Charles T. Anderson, William O. Hancock 2051-Pos Board B509 Travel Award Winner ENGINEERING THE EXTRACELLULAR MATRIX WITH DNA-BASED MOLEC - ULAR FORCE SENSORS. Peter E. Beshay , Melika Shahhosseini, Jonathan W. Song, Carlos E. Castro

2027-Pos Board B485 MACROPHAGES CONNECTION: AGGRESSIVE NANOMECHANICAL PHENOTYPES OF CIRCULATING TUMOR CELLS IN PROSTATE CAN - CER. Pawel A. Osmulski , Alessandra Cunsolo, Meizhen Chen, Yusheng Qian, Chun-Lin Lin, Chia-Nung Hung, DevalingamMahalingam, Nameer B. Kirma, Chun-Liang Chen, Josephine A. Taverna, Michael A. Liss, Ian M. Thompson, Tim H. Huang, Maria Gaczynska 2028-Pos Board B486 STRUCTURE, DYNAMICS AND NANOMECHANICS OF WILD-TYPE AND ALPHA-VARIANT SARS-COV-2 VIRIONS. Dorottya Mudra, Balint Kiss, Zoltán Kis, Bernadett Pályi, Miklós Kellermayer 2029-Pos Board B487 DIRECT CHARACTERISATION OF NON-PRODUCTIVE ATTEMPTS AT STRUCTURAL SELF-ASSEMBLY IN SINGLE BIOLOGICAL MOLECULES. Aaron D. Lyons , Noel Q. Hoffer, Michael T. Woodside Bioengineering (Boards B488 - B509) 2030-Pos Board B488 EDGE RIPPLING AND PETAL SHAPE OF LILIES. Gunnar J. Goetz , Zachary R. Cohen, Thomas Portet, Nicole E. Panek, Sean A. Stephens, Peter N. Holmes, Tamas Varga, Sarah L. Keller 2031-Pos Board B489 Travel Award Winner FULL-LENGTH DYSTROPHIN DEFICIENCY LEADS TO CONTRACTILE AND CALCIUM TRANSIENT DEFECTS IN HUMAN ENGINEERED HEART TIS - SUES. Samantha B. Bremner , Christian J. Mandrycky, Andrea Leonard, Alan R. Levinson, Ethan S. Rehn, J. Manuel Pioner, Nathan J. Sniadecki, David L. Mack 2032-Pos Board B490 PHYSICS-BASED MODELING AND DATA-DRIVEN ALGORITHM FOR PRE - DICTION AND DIAGNOSIS OF ATHEROSCLEROSIS. Mohamed Bahloul , Zehor Belkhatir, Yasser Aboelkassem, Meriem T LALEG-KIRATI 2033-Pos Board B491 HIGH THROUGHPUT ASSESSMENT OF CARDIAC SAFETY VIA CONTRAC - TILITY MEASUREMENTS OF 3D ENGINEERED HEART TISSUES USING A NOVEL INSTRUMENTATION PLATFORM. Bonnie Berry, Alex Jiao, Kevin Gray, Elliott Fisher, Samir Kharoufeh, Shawn M. Luttrell, Nicholas Geisse 2034-Pos Board B492 SUBSTRATE STRESS RELAXATION REGULATES NEURAL STEM CELL FATE COMMITMENT. Eric Qiao , David Schaffer, Sanjay Kumar 2035-Pos Board B493 FIBRILLARY ECM PROTEINS CONTRIBUTE TO TUMOR PROGRESSION. Jen Flournoy , Yun Chen 2036-Pos Board B494 Travel Award Winner CHROMATIN SOFTENING AND NUCLEAR ENVELOPE BREACHING PO - TENTIATES KILLING OF CHEMORESISTANT CANCER CELLS. Junjie Chen , Mingjiu Wang, Tian-Li Wang, Ie-Ming Shih, Yun Chen 2037-Pos Board B495 EXOSOMES ARE PROMISING VECTORS FOR HYDROPHOBIC DRUG DELIV - ERY TO HUMAN CANCER CELLS. William S. Fisher , Christine Tchounwou, Sophia Wei, Logan Roberts, Kai K. Ewert, Cyrus R. Safinya 2038-Pos Board B496 TRACKING DYNAMIC INTERACTION BETWEEN THERAPEUTIC VESICLES AND ENDOCYTIC STRUCTURES. Grant Ashby , Carl Hayden, Jeanne C. Stachowiak

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