Biophysical Society 66th Annual Meeting Program Guide

Cytoskeletal Assemblies and Dynamics (Boards B332 - B356) 2502-Pos Board B332 LIPID DROPLETS DISPLACE CYTOSKELETON & INHIBIT PHAGOCYTOSIS - IMPLICATIONS FOR DYSFUNCTION IN OBESITY. Michael P. Tobin , Dennis Board B333 MODELING CONTRACTILITY KIT MEDIATED MECHANOSENSATION AND CYTOSKELETAL NETWORK ASSEMBLY. Alma I. Plaza-Rodriguez , Douglas N. Robinson, Pablo A. Iglesias 2504-Pos Board B334 SMALL ORGANIC OSMOLYTES ACCELERATE ACTIN FILAMENT ASSEMBLY AND STIFFEN FILAMENTS. Pavlo Kravchuk , Connor L. Harmon, Bryan Demosthene, Ellen H. Kang 2505-Pos Board B335 POLYMERIZATION OF ACTIN INSIDE LIQUID-LIKE PROTEIN DROPLETS DRIVES SPONTANEOUS ACTIN BUNDLING. Kristin Graham , Aly Ladak, Liping Wang, Aravind Chandrasekaran, Padmini Rangamani, Eileen M. Lafer, Jeanne C. Stachowiak 2506-Pos Board B336 SELF-ORGANIZATION IN RECONSTITUTED ACTIN NETWORKS BY COU - PLING MONOMER TURNOVER AND CONTRACTILITY. Philip Bleicher , Andreas R. Bausch 2507-Pos Board B337 CARMIL PROTEINS REGULATE CAPPING PROTEIN TO CONTROL BRANCHED ACTIN NETWORK ARCHITECTURE. Wilson Nieves , Dyche Mullins 2508-Pos Board B338 TENSILE FORCE-INDUCED CYTOSKELETAL REMODELING: MECHANICS BEFORE CHEMISTRY. Xiaona Li, Qin Ni, Xiuxiu He, Jun Kong, Soon-Mi Lim, Garegin A. Papoian, Jerome P. Trzeciakowski, Andreea Trache, Yi Jiang 2509-Pos Board B339 FAST ACTIN DISASSEMBLY AND MECHANOSENSITIVITY OF THE ACTIN CROSSLINKER FIMBRIN DURING CLATHRIN-MEDIATED ENDOCYTO - SIS. Sayed Iman Mousavi , Xiaobai Li, Julien Berro 2510-Pos Board B340 COUNTERACTIVE EFFECTS OF ELECTROSTATICS AND MACROMOLECU - LAR CROWDING ONACTIN BUNDLE MECHANICS, ORGANIZATION, AND SECONDARY STRUCTURE. Nicholas Castaneda, Briana Lee, Cecile Feuillie, Jinho Park, Michael Molinari, Laurene Tetard, Ellen H. Kang 2511-Pos Board B341 DESIGN PRINCIPLES OF ENDOCYTIC ACTIN ARCHITECTURE AND FORCE PRODUCTION. Matthew Akamatsu , Daniel Serwas, Leanna M. Owen, Padmini Rangamani, David G. Drubin 2512-Pos Board B342 NETWORK SHIFTS AWAY FROM BRANCHED ACTIN FORMATION PRO - MOTE THE UNIQUELY LONG GROWTH OF TUNNELING NANOTUBES. J. Michael Henderson , Nina Ljubojevic, Thibault Chaze, Quentin Giai Gianetto, Stéphanie Descroix, Patricia M. Bassereau, Chiara Zurzolo 2513-Pos Board B343 COOPERATIVE DYNAMICS OF CURVATURE-SENSING PROTEINS CONTROL CYTOSKELETAL ASSEMBLY NEAR THE PLASMA MEMBRANE. Haoran Ni , Garegin A. Papoian E. Discher 2503-Pos

2489-Pos Board B319 PASSIVE AND ACTIVE MECHANICAL PROPERTIES OF TITIN STUDIED IN INTACT FROG MUSCLE FIBERS UPON INHIBITION OF MYOSIN MOTORS BY PARA-NITRO-BLEBBISTATIN. Caterina Squarci , Pasquale Bianco, Massimo Reconditi, Irene Pertici, Marco Caremani, Theyencheri Narayanan, Adam I. Horvath, Andras Malnasi-Csizmadia, Marco Linari, Vincenzo Lombardi, Gabriella Piazzesi 2490-Pos Board B320 REGULATING METABOLIC RATE VIA SKELETAL MYOSIN SUPER RELAXED STATE. Clyde F. Wilson , Nariman I. Naber, Roger Cooke 2491-Pos Board B321 EMBRYONIC MYOSIN MUTATIONS T187I AND R672C RESULT IN MECHANI - CAL AND STRUCTURAL DYSFUNCTION IN HIPSC DERIVED SKELETAL MYO - TUBES. Saffie Mohran , Matthew C. Childers, Christian Mandrycky, Shawn M. Luttrell, Kati Buckingham, Michael Bamshad, David L. Mack, Michael Regnier 2492-Pos Board B322 DIRECT AND SELECTIVE MYOSIN-INHIBITION STABILIZES THE SUPER- RELAXED STATE OF MYOSIN AND BLUNTS POST-TETANIC POTENTIATION IN FAST-SKELETAL MUSCLE. Breanne Stamper, Sarah Lehman, Molly Madden, Mike DuVall, Ying Qian, Marc Evanchik, Ben Barthel, Carlos L. del Rio , Alan Board B323 THE MECHANISM OF COOPERATIVITY IN THIN FILAMENT ACTIVATION STUDIED IN DEMEMBRANATED FIBERS OF SLOW SKELETAL MUSCLE. Mat - teo Marcello, Cristina Gallart, Irene Pertici, Massimo Reconditi, Gabriella Piazzesi, Vincenzo Lombardi, Marco Linari, Marco Caremani 2494-Pos Board B324 DEFINITION OF THE MECHANOKINETIC PARAMETERS ACCOUNTING FOR THE FUNCTIONAL DIVERSITY OF SLOW AND FAST ISOFORMS OF SKELETAL MUSCLE MYOSIN WITH A SYNTHETIC NANOMACHINE. Valentina Buonfiglio , Irene Pertici, Vincenzo Lombardi, Duccio Fanelli, Pasquale Bianco 2495-Pos Board B325 STRUCTURAL BASIS OF THE SUPER-RELAXED AND HYPER-RELAXED STATE OF MYOSIN II. Roger Craig , Raul Padron 2496-Pos Board B326 CHARACTERIZATION OF S100A1/N2A-IS INTERACTION IN TITIN. Sabrina I. Apel , Emily Schaffter, Matthew Gage 2497-Pos Board B327 TROPONIN C MUTATIONS ALTER TWITCH KINETICS AND FORCE-FREQUEN - CY RELATIONSHIP OF FAST AND SLOW TWITCH SKELETAL MUSCLE. Kyra K. Peczkowski-Weishaar , Connor Tyree, Jill A. Rafael-Fortney, Svetlana Tikunova, Jianchao Zhang, Paul M.L. Janssen, Jonathan P. Davis 2498-Pos Board B328 THE IMPORTANCE OF SHORTENING DEACTIVATION TO DIFFERENT MUSCLE TYPES. Amy Loya, Bernadette Glasheen, Sarah Van Houten, Douglas M. Swank 2499-Pos Board B329 MYOSIN OFF-ON TRANSITION MODULATES THE SIMPLE HARMONIC MO - TION OF TROPOMYOSIN COUPLING LENGTH-DEPENDENT ACTIVATION AND THE ACTOMYOSIN CHEMOMECHANICAL CYCLE. James J. Earley 2500-Pos Board B330 CALMODULIN INTERACTIONS WITHIN THE N2A REGION OF TITIN. Emily Schaffter , Sabrina Apel, Matthew J. Gage 2501-Pos Board B331 ANTI-S2 PEPTIDES AND ANTIBODIES BIND COOPERATIVELY TO THE MYO - SIN DIMER WITH HIGH AFFINITY AND STABILIZE THE UNFOLDED STATE OF S2. Dua'a Quedan , Douglas D. Root J. Russell 2493-Pos

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