Biophysical Society 66th Annual Meeting Program Guide

Sara Mingu , Johannes Gutenberg University 966-Pos, B107 DECIPHERING THE STRUCTURE AND FUNCTION OF FG-NUCLEOPORINS IN SITU USING FLIM-FRET. Viviana Monje-Galvan , University at Buffalo, SUNY 1088-Pos, B229 MODELING PROTEIN-LIPID INTERACTIONS IN MECHANISMS OF CELL DEATH. Trung Nguyen , University of Texas at Austin 1339-Pos, B480 FULL-SPECTRUM MULTIPHOTON AUTOFLUORESCENCE IMAGING WITH TEMPORAL FOCUSING. Soon Woo Park , Sungkyunkwan University 1327-Pos, B468 DEVELOPMENT OF AN ACCELERATED SIMULATION TECHNIQUE FOR EXPLORING PROTEIN TRANSITION PATHWAYS. Iuliia Polina , University of Minnesota Medical School 1150-Pos, B291 EXPRESSIONOF SARS-COV-2-ORF3APROTEIN INDUCESCARDIOMYOCYTE DAMAGE. Ahmed Ramadan , Dalhousie University AFTERDEPOLARISATIONS IN THE ZEBRAFISH HEART. Robyn Rebbeck , University of Minnesota 845-Plat FRET ASSAYS FOR RYR-TARGETED DRUG DISCOVERY PLATFORMS. Yuan Ren , Yale University 1117-Pos, B258 FORCE REDISTRIBUTION DURING CLATHRIN-MEDIATED ENDOCYTOSIS IS REVEALED BY NEW PHASE-SEPARATING FORCE SENSORS. Jacob Ritz , University of Minnesota, Twin Cities 1359-Pos, B500 CHARACTERIZATION AND APPLICATION OF DIFFUSION CONTRAST PALM (DCPALM) TO STUDY PROTEIN INTERACTIONS AT HIGH BACKGROUND. Moises Romero , University of California, Irvine 1037-Pos, B178 PROBING REMDESIVIR NUCLEOTIDE ANALOGUE INSERTION TO SARS- COV-2 RNA DEPENDENT RNA POLYMERASE IN VIRAL REPLICATION. Urska Rovsnik , Stockholm University 1177-Pos, B318 FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF A NOVEL PH-MODULATED OPEN STATE OF A PENTAMERIC LIGAND-GATED ION CHANNEL. Iker Soto Santarriaga , University of Notre Dame 892-Pos, B33 THE CLPX TRANSLOCASE AND ITS APPLICATION TO THE STUDY OF VECTORIAL PROTEIN FOLDING IN VITRO. Nadia Sarfraz , Georgetown University 1011-Pos, B152 FLUORESCENCE LIFETIME IMAGING MICROSCOPY (FLIM) FOR TRACKING RNA DYNAMICS IN LIVE MAMMALIAN CELLS. 1128-Pos, B269 OPTOGENETIC SUPPRESSION OF DRUG-INDUCED EARLY

Alexandra Schwartz , Vanderbilt University 1212-Pos, B353 STRUCTURAL CHARACTERIZATION OF THE HUMAN SEROTONIN TRANSPORTER'S N-TERMINUS. Elanor Sievers , University of California, San Diego 879-Pos, B20 STRUCTURE DETERMINATION AND OPTIMIZATION OF A CYSTEINE- LESS INTEIN WITH NMR SPECTROSCOPY AND MOLECULAR DYNAMICS SIMULATIONS. Whitney Stevens-Sostre , University of Wisconsin-Madison 1158-Pos, B299 CONFORMATION SENSITIVE ANTIBODY REVEALS AN ALTERED CYTOSOLIC PAS/CNBH ASSEMBLY DURING HERG CHANNEL GATING. Naveen Thakur , University of Florida RECEPTOR CONFORMATIONAL DYNAMICS BY ENDOGENOUS PHOSPHOLIPIDS. Yingzi Xia , Johns Hopkins University 894-Pos, B35 STUDYINGTHEREFOLDABILITYOFTHEPROTEOMEUSINGCROSSLINKING MASS SPECTROMETRY. Navin Verma , Lee Kong Chian School of Medicine 854-Plat A NEW K CA 3.1 CHANNEL ACTIVATOR SKA-346 BOOSTS T-CELL ANTITUMOR RESPONSE IN THE IMMUNE SUPPRESSIVE MICROENVIRONMENT. Cecilia Bores , Union College 1015-Pos, B156 A COARSE-GRAINED REPRESENTATION OF DNA IMMERSED IN AN EXTERNAL PROTEIN FORCE-FIELD. Tuesday, February 22 Yasser Aboelkassem , University of Michigan - Flint 1848-Pos, B306 MACHINE LEARNINGMODEL PREDICTS THE EFFECTS OF TROPOMYOSIN RIGIDITY ON CARDIAC MUSCLE CONTRACTION. Lisandra Flores Aldama , University of Wisconsin-Madison 1429-Plat A HYDROPHOBIC NEXUS AT THE PAS-CAP/GLOBULAR PAS/CNBHD INTERFACE TUNES DEACTIVATION KINETICS OF HERG CHANNELS. Anamika Avni , Indian Institute of Science Education and Chemical Sciences 1485-Plat SINGLE-DROPLET VIBRATIONAL RAMAN SPECTROSCOPY ILLUMINATES THE INNER WORKINGS OF PHASE-SEPARATED BIOMOLECULAR CONDENSATES. Cisloynny Beauchamp-Perez , University of Colorado at Denver 1681-Pos, B139 C2 DOMAIN LYSINE CLUSTERS ARE HIGHLY SUSCEPTIBLE TO NON- ENZYMATIC POST-TRANSLATIONAL MODIFICATIONS. 938-Pos, B79 REGULATION OF HUMAN A 2A ADENOSINE

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