Biophysical Society 66th Annual Meeting Program Guide

378-Pos Board B202 PREDICTING AFFINITIES OF PROTEIN-LIPID INTERACTIONS USING MOLEC - ULAR SIMULATIONS. T. Bertie Ansell, Wanling Song, Michael R. Horrell, Tanadet Pipatpolkai, Mark S. Sansom, Phillip J. Stansfeld, Robin A. Corey 379-Pos Board B203 FREE ENERGY PROFILES FOR PEPTIDE-LIPID MEMBRANE DISSOCIATION FROM ATOMISTIC AND COARSE GRAINED MOLECULAR DYNAMICS SIMU - LATIONS. Ryan Smith , Ioan Kosztin 380-Pos Board B204 PREDICTING INTERFACIAL PARTITIONING INTO ZWITTERIONIC AND AN - IONIC MEMBRANES. Victor Vasquez Montes , Alexey Ladokhin 381-Pos Board B205 RHODOPSIN ACTIVATION INVOLVES AN ENSEMBLE OF CONFORMATION - AL SUBSTATES. Andrey V. Struts, Eglof Ritter, Paul Fischer, Blake Mertz, Franz Bartl, Michael F. Brown 382-Pos Board B206 MOLECULAR MECHANISM OF SOUND AMPLIFICATION IN MAMMALIAN HEARING SYSTEM. Sepehr Dehghanighahnaviyeh , Zhiyu Zhao, Emad Tajkhorshid 383-Pos Board B207 THE IMPACT OF PROTEIN CHARGE AND CHOLESTEROL ON HUNTINGTIN/ LIPID INTERACTIONS. Alyssa R. Stonebraker , Justin A. Legleiter 384-Pos Board B208 EFFECTS OF CHARGE ON THE INTERACTION OF THE HUNTINGTIN N- TERMINAL SEQUENCE WITH MODEL CELL MEMBRANES. Abigail Reitz , Shelli L. Frey 385-Pos Board B209 Travel Award Winner INTERACTION OF THE HUNTINGTIN N-TERMINAL SEQUENCE WITH MODEL CELL MEMBRANES. Jordyn Markle , Shelli L. Frey 386-Pos Board B210 BLOCKING AMYLOID LIPID INTERACTION AS A THERAPEUTIC STRAT - EGY. Chathuranga Siriwardhana , Justin A. Legleiter 387-Pos Board B211 INVESTIGATING THE THERAPEUTIC POTENTIAL OF MITOCHONDRIAL-TAR - GETED SYNTHETIC TETRAPEPTIDES IN AMYLOIDOGENIC DISEASES. Ashley Reed , Hazel Szeto, Andrei T. Alexandrescu, Nathan N. Alder 388-Pos Board B212 KEY MEMBRANE LIPIDS CAN ALTER THE RESILIENCY OF NEURONAL CELLS TO PROTEIN MISFOLDED OLIGOMER TOXICITY. Ryan P. Kreiser , Aidan K. Wright, Liam R. Sasser, Tristan L. McKenzie, Lam T. Nguyen, Ryan Limbocker 389-Pos Board B213 PHOSPHOLIPID ACYL CHAIN LENGTH AND DEGREE OF UNSATURATION MODULATE Α-CRYSTALLIN BINDING TO THE MEMBRANE. Geraline Trossi-Torres , Raju Timsina, Laxman Mainali 390-Pos Board B214 ALPHA-CRYSTALLIN INTERACTS WITH THE MODEL OF HUMAN EYE LENS-LIPID MEMBRANE VIA HYDROPHOBIC INTERACTION. Raju Timsina, Geraline Trossi-Torres, Jackson Thieme, Matthew O’Dell, Nawal Khadka, Laxman Mainali 391-Pos Board B215 PHASE SEPARATION STUDIES OF ANIONIC LIPIDS AND TAU IN BIOLOGI - CALLY RELEVANT CONDITIONS. Christine Tchounwou , Dylan Lasher, Bret - ton Fletcher, Rebecca L. Best, Herb P. Miller, Leslie Wilson, S. C. Feinstein, Cyrus R. Safinya

365-Pos Board B189 FUSION PEPTIDE FROM SARS-2 SPIKE TRANSFORMS INTO A WEDGE IN - SERTED IN A BILAYER LEAFLET, AND THINS THE OPPOSITE LEAFLET. Steven R. Van Doren , Benjamin Scott, Yan G. Fulcher, Rama K. Koppisetti 366-Pos Board B190 ELUCIDATING THE DISTINCT STRUCTURAL FEATURES OF THE SARS-COV-2 SPIKE PROTEIN FUSION DOMAIN. Daniel Birtles 367-Pos Board B191 DEVELOpmENT OF A SARS-COV-2 VIRUS-LIKE PARTICLE THAT PERFORMS AS A DIRECT CELL ENTRY REPORTER. Elena Mekhedov, Matthias Garten , Glen Humphrey, Jennifer D. Petersen, Adriana E. Golding, Hang Waters, Joshua Zimmerberg 368-Pos Board B192 REVEALING VIRUS-HOST MEMBRANE FUSION MECHANISMS USING OPTI - CAL TWEEZERS. Inbal Lupovitz , Natasha D. Durham, James B. Munro, Raya Sorkin 369-Pos Board B193 LASSA VIRUS GLYCOPROTEIN-MEDIATED MEMBRANE FUSION WITH EN - DOSOMAL MODEL MEMBRANES. Laura Odongo , Volker Kiessling, Judith M. White, Lukas K. Tamm 370-Pos Board B194 POST-HEMIFUSION STAGES OF LASSA VIRUS GPC-MEDIATED FUSION WITH ENDOSOMES ARE AUGMENTED BY A LATE ENDOSOME-RESIDENT LIPID. Ruben M. Markosyan , Mariana Marin, You Zhang, Fredric S. Co - hen, Gregory B. Melikyan 371-Pos Board B195 EXPLORING REVERSIBILITY AND COOPERATIVITY IN MODELING FLAVIVI - RUS MEMBRANE FUSION. Tasnim Anika , Robert J. Rawle 372-Pos Board B196 CHARACTERIZATION OF SENDAI VIRUS BINDING TO SUPPORTED LIPID BILAYERS AT THE SINGLE-VIRUS LEVEL. Amy Lam , Papa Freduah A. Ander - son, Orville O. Kirkland, Robert J. Rawle General Protein-Lipid Interactions (Boards B197 - B229) 373-Pos Board B197 PROBING THE PIP2 DEPENDENCE OF THE ASAP1 PH DOMAIN MEM - BRANE BINDING BY NMR AND MD SIMULATIONS. Olivier Soubias , Shashank Pant, Yue Zhang, Emad Tajkhorshid, Robert A. Byrd 374-Pos Board B198 THE PRIMARY STRUCTURE OF THE CYTOPLASMIC TAIL DOMAIN OF IN - FLUENZA HEMAGGLUTININ REGULATES ITS CO-CLUSTERING WITH PHOS - PHATIDYLINOSITOL 4,5-BISPHOSPHATE. Jaqulin N. Wallace , Matthew T. Parent, Prakash Raut, Hang Waters, Joshua Zimmerberg, Samuel T. Hess 375-Pos Board B199 A CRITICAL ROLE FOR CHOLESTEROL IN PI(4,5)P 2 - DEPENDENT UNCON - VENTIONAL SECRETION OF FIBROBLAST GROWTH FACTOR 2. Fabio Lolicato , Roberto Saleppico, Alessandra Griffo, Britta Bruegger, Karin Jacobs, Ilpo Vattulainen, Walter Nickel 376-Pos Board B200 MECHANISTIC ANALYSIS OF PHOSPHOINOSITIDE CONVERSION AND TETHERING. Hannes Maib, David H. Murray 377-Pos Board B201 MICROSCOPIC VIEW OF INTERACTION AND BINDING OF SRC-SH2 DO - MAIN TO PLASMA MEMBRANE. Hale S. Hasdemir , Emad Tajkhorshid

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