Biophysical Society 66th Annual Meeting Program Guide

Exhibitor Presentation Bruker 10:30 am - 12:00 pm, Esplanade, Room 158 Symposium Future of Biophysics Burroughs Wellcome Fund Symposium 10:45 am - 12:45 pm, South, Level Three, Room 301/302 Support contributed by the Burroughs Wellcome Fund Co-chairs Elizabeth Komives, University of California, San Diego, USA Arthur G. Palmer, III, Columbia University, USA No Abstract 10:45 am SEQUENCE- AND CHEMICAL SPECIFICITY DEFINE THE FUNCTIONAL LAND - SCAPE OF INTRINSICALLY DISORDERED REGIONS. Alex S. Holehouse No Abstract 11:15 am INFLAMMASOME ASSEMBLY - AN EXAMPLE OF BALANCE CONTROL IN THE IMMUNE SYSTEM. Liman Zhang No Abstract 11:45 am EMBRACING DYNAMICS: DISTINCTIVE FEATURES OF MULTIVALENT IDP ASSEMBLIES IN CELL GROWTH REGULATION. Afua Nyarko No Abstract 12:15 am LIVE-CELL MICROMANIPULATION OF A GENOMIC LOCUS REVEALS INTER - PHASE CHROMATIN MECHANICS. Antoine Coulon Symposium Mechano-Electrical Signaling in Cardiac Cells 10:45 am - 12:45 pm, South, Level Three, Room 303/304 Chair W Jonathan Lederer, University of Maryland, USA 752-Symp 10:45 am DNA TENSION PROBES SHOW THAT CARDIOMYOCYTE MATURATION IS SENSITIVE TO PICONEWTON SCALE TRACTION FORCES. Khalid Salaita , Sk Aysha Rashid, Aaron T. Blanchard, Hee C. Cho, Natasha Fernendez 753-Symp 11:15 am CARDIOMYOCYTE T-TUBULAR FLUID PUMPING. Eva A. Rog-Zielinska, 11:45 am AUTOREGULATION OF EXCITATION-CA 2+ SIGNALING-CONTRACTION IN CARDIOMYOCYTE UNDER MECHANICAL LOAD. Ye Chen-Izu , Zhong Jian, Bence Hegyi, Rafael Shimkunas, Mohammad A. LariKazemi Lari, John A. Shaw, Donald M. Bers, Kit S. Lam, Leighton T. Izu 755-Symp 12:15 pm MECHANO-CHEMO-ELECTRIC SIGNALING IN HEART: HOW LOCAL BLOOD FLOW IS REGULATED. Guiling Zhao, W. Jonathan Lederer Platform Protein Structure, Prediction, and Design 10:45 am - 12:45 pm, South, Level Two, Room 201/202/203 Co-Chairs Daniel Schmidt, University of Minnesota, USA Lauren Porter, NIH, USA 756-Plat 10:45 am FAST, ACCURATE ANTIBODY STRUCTURE PREDICTION FROM DEEP LEARN - ING ON MASSIVE SET OF NATURAL ANTIBODIES. Jeffrey A. Ruffolo , Jeffrey J. Gray Peter Kohl 754-Symp

time scales accessible to EPR experiments, coupled with its high sensitiv - ity compared to other techniques, EPR has been invaluable in advancing knowledge of many biological processes. Analysis of line shapes yields the desired information. Bruker now offers the SpinFit Liquids software module to easily extract information regarding the motional dynamics. Fitting of spectra is fully implemented and multiple species can be ana - lyzed simultaneously. The module is compatible with all current Bruker spectrometers. DEER (Double Electron Electron Resonance) has proven to be very successful in structural biology studies. Each sample is pre-screened to evaluate the labelling efficiency. With the introduction of the Bruker Magnettech ESR5000, we now offer a reasonably priced benchtop op - tion (about the size of a UV/Vis spectrometer) that has the sensitivity to acquire the spectra and also is available with the optional SpinFit Liquids and SpinCount modules to ascertain the labelling efficiency. Screening is performed off-line, thus not interfering with the on-going DEER experi - ments to increase lab productivity. In addition, the spectrometer helps in pre-screening DNP samples. EPR accessibility measurements are a valuable molecular ruler for peptides and proteins in membranes for structural studies. The Bruker Magnettech ESR5000 enables this important experimental technique. Rapid Scan EPR offers improvements in sensitivity. We invite you to see the latest results applying the technique to biophysical studies. Speakers Clemens Anklin, Vice President of NMR Applications, Bruker Biospin Ralph Weber, Senior Applications Scientist, Bruker Biospin Exhibits 10:00 am - 5:00 pm, Exhibit Hall ABC Meet the Editors, The Biophysicist 10:15 am - 11:00 am, South Lobby/Publications Booth Take this opportunity to meet editors of The Biophysicist . Editors will be available to talk about the journal and answer questions about where you should submit your work, what will help to get your work published, and what you can expect when you submit. Associate Editors Gundula Bosch and Patricia Soto will attend. Coffee Break Calling all new BPS members! Come and mingle with BPS Staff, Society Council, and Committee members as you learn about the Society’s activities. Current members are welcome to come and meet with new members. Career Development Center Workshop Networking for Biophysicists: How to Create Your Unicorn Career 10:30 am - 11:30 am, Esplanade, Room 151 In this session, we will discuss how to leverage networking to create a unique, customized career, which we call Your Unicorn Career. We will address how to understand your unique value, skills and interests and how to align that with employers who will hire you. We will discuss vari - ous methods for finding and building win-win collaborations with people in different professions and pathways to create opportunities for your unicorn career to come to fruition. 10:15 am - 11:00 am, Exhibit Hall ABC New Member Welcome Coffee 10:15 am - 11:15 am, Esplanade, Room 155

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