Biophysical Society 67th Annual Meeting Program Guide

Exhibitor Presentation Sutter Instrument 4:30 pm - 6:00 pm, Room 10

Dinner Meet-Ups 6:00 pm - 6:30 pm, Lobby BC/Society Booth

Interested in making new acquaintances and experiencing the cuisine of San Diego? Meet at the Society Booth each evening Sunday through Tuesday at 6:00 pm, where a BPS member will coordinate dinner at a local restaurant. Awards and 2023 Biophysical Society Lecture 8:00 pm - 9:30 pm, Room 6 PRESENTATION OF AWARDS 8:00 pm 871-Natl 8:30 pm HOW DO YOU FEEL? THE MOLECULES THAT SENSE TOUCH. Ardem Patapoutian

M O N D A Y

Scientists Empowering Scientists For almost 50 years, Sutter Instrument has been collaborating with researchers. During this period, there have been many technological evolutions in both imaging and patch clamp electrophysiology. Sutter has introduced many new product families, including pipette pullers, ma nipulators, light sources, wavelength switchers, specialized microscopes and, most recently, fully integrated patch clamp amplifier systems. At this presentation, we will teach techniques, tips and tricks for both pipette fabrication and electrophysiology, and showcase new products, such as the Lambda 721 Optical Beam Combiner and the NAN™ Open-Design Upright Microscope. Registration is available online through the Sutter Event Registration Page (https://sutter.eventbrite.com). The number of available spaces is limited, and registrations are accepted on a first-come-first-served basis. Speakers Chris Ballard, Vice President, Sutter Instrument Adair Oesterle, Support Engineer, Sutter Instrument Telly Galiatsatos, Product Manager, Patch Clamp Systems, Sutter Instru ment Exhibitor Presentation Elements srl 5:30 pm - 7:00 pm, Room 9 Nanopore Measurements At 10 MHz Bandwidth: Let’s See the Hidden Data You Were Looking For! From its introduction in February 2022 of the new 10 MHz bandwidth Nanopore Reader, several labs have started to use our new powerful instrument, featuring unprecedent results and signal quality in high band width nanopore measurements. We will present data from a recent work of Prof. Marija Drndic about ultrafast translocation and dynamics of double stranded DNA through a nanopore at 10 MHz bandwidth with acquisition of data points per 25 nanoseconds (150 MB/s). By introducing a rigorous algorithm, it was accurately identified each current level present within events. Remark able sensitivity of this system reveals distortions of short-lived states at a lower bandwidth. This work develops broadly applicable methods that will help uncover a wide range of biomolecular dynamics at unprecedent edly small timescales. 10 MHz bandwidth allows to observe protein conformation and kinetics never observed before: here we present the latest results from protein measurements. Speakers Marija Drndic, Professors of Physics, University of Pennsylvania Federico Thei, CEO, Elements srl

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