Biophysical Society 67th Annual Meeting Program Guide

861-plat 5:30 pm MECHANISM OF UREA AND TMAO COUNTERACTION IN LIPID MEM BRANE INTERACTIONS. Yuri Shakhman, Ilan Shumilin, Daniel Harries 862-plat 5:45 pm CAN CELL PENETRATING PEPTIDES ENTER VIA MEMBRANE FUSION? Katarína L. Baxová, Mattia I. Morandi, Ori Avinoam, Pavel Jungwirth Platform

850-plat 4:45 pm STRUCTURAL DETERMINANT OF THE IVABRADINE-INDUCED BLOCK OF PACEMAKER HCN CHANNELS. Andrea Saponaro , Alessandro Porro, Jan H. Krumbach, Atiyeh Sadat Sharifzadeh, Antonio Chaves-Sanjuan, Dario DiFrancesco, Kay Hamacher, Gerhard Thiel, Anna Moroni 851-plat 5:00 pm ACTIVATION OF THE ALKALINE-ACTIVATED K 2P K + CHANNEL TALK-2 REQUIRES OPENING OF TWO FUNCTIONALLY COUPLED GATES. Lea C. Neelsen , Elena B. Riel, Susanne Rinné, Björn C. Jürs, Aytug K. Kiper, Bisher Eymsh, Mauricio Bedoya, Jan Langer, Niels Decher, Thomas Baukrowitz, Marcus Schewe 852-plat 5:15 pm ACUTE PKA MODULATION OF THE CARDIAC SODIUM CURRENT IS MEDI ATED BY 14-3-3. Yang Zheng , Angelina Ramirez-Navarro, Haiyan Liu, Snizhana Chorna, Xiaoping Wan, Isabelle Deschenes 853-plat 5:30 pm HIGH-SPEED AFM IMAGING OF VOLTAGE GATED SODIUM CHANNEL NACHBAC AND VOLTAGE APPLICATION. Motonori Imamura , Atsushi Miyagi, Shuai Gao, Nieng Yan, Simon Scheuring 2521-Pos 5:45 pm FUNCTIONAL DIFFERENCES BETWEEN VOLTAGE-GATED PROTON CHAN NELS FROM FLOWERING AND NON-FLOWERING PLANTS. Chang Zhao, Parker D. Webster, Alexis De Angeli, Francesco Tombola Platform Membrane Physical Chemistry 4:00 pm - 6:00 pm, Room 5AB Co-Chairs 855-plat 4:00 pm OSMOTIC PRESSURE ENABLES FACILE HIGH YIELD ASSEMBLY OF CELL-LIKE GIANT UNILAMELLAR VESICLES IN SOLUTIONS OF PHYSIOLOGICAL IONIC STRENGTH. Alexis Cooper , Vaishnavi Girish, Anand B. Subramaniam 856-plat 4:15 pm INTRINSIC STIFFENING AND DYNAMIC SOFTENING BY CHOLESTEROL. Amirali Hossein, Teshani Kumarage, Rana Ashkar, Alexander J. Sodt 857-plat 4:30 pm THE EFFECT OF PLASMA MEMBRANE ARCHITECTURE ON THE TRANS PORT PROPERTIES AND REACTION KINETICS OF MEMBRANE ASSOCIATED PROTEINS. Sankarshan Talluri , Satyajit Mayor 858-plat 4:45 pm FUSION MODIFIES THE MATERIAL PROPERTIES OF MEMBRANES. Rafael B. Lira , Ceri Richards, Rafaela R. M. Cavalcanti, Christoffer Aberg, Karin A. Riske, Wouter H. Roos 859-plat 5:00 pm COMPARING CELL WALL AND MEMBRANE CONTRIBUTIONS TO MESO PHYLL CONDUCTANCE IN PLANTS. Daipayan Sarkar , Martin Kulke, Isaiah Kaufman, Josh V. Vermaas 860 -plat 5:15 pm TOWARDS PRECISE OPTICAL MEASUREMENTS OF STEADY STATE OF- AND SMALL CHANGES IN RESTING MEMBRANE POTENTIALS. Debjit Roy , Xavier Michalet, Kiran Bharadwaj, Evan W. Miller, Yijie Wang, Arjun Deb, Michael A. Wayne, Claudio Bruschini, Edoardo Charbon, Mahbanoo Vakili, Robert Gunsalus, Robert T. Clubb, Shimon Weiss Rafael Lira, University of Groningen, The Netherlands Peter Pohl, Johannes Kepler University Linz, Austria

M O N D A Y

Molecular Dynamics II 4:00 pm - 6:00 pm, Room 11AB

Co-Chairs Iain Smith, University of Southampton, United Kingdom Ryan Woltz, University of California, Davis, USA

863-plat 4:00 pm METHODS FOR STABLE MULTIMERIC MOLECULAR DYNAMICS SIMULA TION AND MODELING OF CARDIAC SK2 CHANNEL FUNCTION. Ryan L. Woltz , Nipavan Chiamvimonvat, Vladimir Yarov-Yarovoy, Kevin DeMarco, Adith Srivatsa, Igor V. Vorobyov, Diego Lopez Mateos, Phuong T. Nguyen, Brandon J. Harris, Khoa Ngo 10 , Xiao-Dong Zhang 11 864-plat 4:15 pm ROBOSAMPLE: A SOFTWARE USING CONSTRAINED MOLECULAR DYNAM ICS COUPLED WITH GIBBS SAMPLING TO INVESTIGATE MACROMOL ECULES. Laurentiu Spiridon , Teodor A. Sulea, Victor G. Ungureanu, Eliza C. Martin, David D.L. Minh 865-plat 4:30 pm Travel Award Winner ALLOSTERIC INHIBITION VIA NONPOLAR TERPENOID INHIBITORS. Anika J. Friedman , Michael R. Shirts, Jerome M. Fox 866 -plat 4:45 pm ULTRAFAST GENERATION OF ATOMISTIC BIOMOLECULAR TRAJECTORIES FOR METHODS DEVELOPMENT. John D. Russo , Daniel M. Zuckerman 867-plat 5:00 pm THE PROTON TRANSFER MECHANISM OF THE RAS GTPASES, THE EFFECT OF THE GTPASE ACTIVATING PROTEIN, AND ONCOGENIC MUTATIONS. Dénes Berta , Sascha Gehrke, Edina Rosta 868 -plat 5:15 pm COMPLEXITY MATTERS: POLYMYXINS AND THE E. COLI CELL ENVELOPE. Iain P.S. Smith , Conrado Pedebos, Syma Khalid 869-plat 5:30 pm MOLECULAR SIMULATIONS REVEAL CHEMOMECHANICAL FORCES DRIV ING BACTERIAL GLIDING MOTILITY. Jacob Miratsky , Abhishek Trivedi, John W. Vant, Abhishek Shrivastava, Abhishek Singharoy 870-plat 5:45 pm SCRUTINIZING THE PROTEIN HYDRATION SHELL FROMMD SIMULATIONS AGAINST SAXS/SANS DATA FROM A WORLDWIDE ROUND ROBIN BENCH MARK. Johanna-Barbara Linse , Jochen S. Hub Speed Networking 4:30 pm - 6:00 pm, Ballroom Lobby Career development and networking is important in science but it can be a big time commitment. Attend this session for an opportunity to meet several attendees and make meaningful connections, all in just 2 hours. Advanced registration is preferred.

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