Biophysical Society 67th Annual Meeting Program Guide

1207-pos Board B336 ELECTRICAL IMPEDANCE SPECTROSCOPY FOR DRUG SCREENING ON LIGAND-GATED ION CHANNELS. Ralf Hausmann , Linhan Cheng, Yuan Cao, Oscar Liborio, Uwe Schnakenberg 1208-pos Board B337 MOLECULAR BASIS FOR INACTIVITY OF MAMMALIAN DELTA IGLURS. Giulio Rosano 1209-pos Board B338 INHIBITION MECHANISM OF AMPA RECEPTORS BY THE PORE BLOCKER MEMANTINE. Elisa Carrillo , Cuauhtemoc U. Gonzalez, Vasanthi Jayara man 1210-pos Board B339 IT IS POSSIBLE TO CALCULATE AGONIST EFFICIENCY FROM RECEPTOR STRUCTURE. Dinesh Indurthi , Mrityunjay Singh, Shailendra Asthana, Anthony Auerbach 1211-pos Board B340 DEREPRESSION MASQUERADES AS ACTIVATION IN A PENTAMERIC LIGAND-GATED ION CHANNEL. Corrie J.B. daCosta , Christian J.G. Tessier, Johnathon R. Emlaw, Raymond M. Sturgeon 1212-pos Board B341 FUNCTIONAL MODULATION OF A PH-SENSITIVE ION CHANNEL BY A TRANSPORTER FAMILY. Mette H. Poulsen , Feng Xue, Svetlana R. Maurya, Stefanie Kickinger, Samuel Usher, Petrine Wellendorph, Alicia Lundby, Stephan A. Pless 1213-pos Board B342 Travel Award Winner STRUCTURAL CHARACTERIZATION OF A FULL-LENGTH HETEROMERIC GLYCINE RECEPTOR IN MULTIPLE FUNCTIONAL STATES. Eric Gibbs , Em ily Krueger, Arvind Kumar, Seiferth David, Serban Ilca, Philip C. Biggin, Sudha Chakrapani 1214-pos Board B343 PHARMACOLOGY OF P2X 3 AND P2X 2/3 RECEPTORS: AN AUTOMATED PATCH CLAMP STUDY. Elena Sirtori, Jean-Francois Rolland , Elena L. Budusan, Giustina M. Rotordam, Tom A. Goetze, Nadine Becker, Alison Obergrussberger, Timothy Strassmaier, Andrea Bruggemann, Michael George, Niels Fertig 1215-pos Board B344 Travel Award Winner NANODISC SCAFFOLD ALTERS THE STRUCTURE OF A PENTAMERIC LIGAND-GATED ION CHANNEL REVEALING NEW CONFORMATIONS. Vi kram Dalal , John T. Petroff, Noah M. Dietzen, Wayland W. Cheng 1216-pos Board B345 STRUCTURAL-FUNCTIONAL CHARACTERIZATION OF KCNJ2 VARIANTS ASSOCIATED WITH VENTRICULAR ARRHYTHMIC SYNDROME PHENO TYPES. Saba Munawar , Chris Wang, Molly Melnick, Louise Reilly, Corey Anderson, Lee L. Eckhardt 1217-pos Board B346 SIGMA CONOTOXIN GVIIIA: BINDING TO 5HT 3A WITH MICROSECOND SIMULATIONS AND DOCKING OF DIVERSE STRUCTURES. Robert Allsopp , Jeffery B. Klauda 1218-pos Board B347 BREAKING BRAINS AND BARRIERS: A NOVEL APPROACH TO STUDY ING NEUROTRANSMITTER RECEPTOR PROTEIN-PROTEIN INTERAC TIONS. Austin D. Rodgers , Michaela Jansen 1219-pos Board B348 EFFECTS OF RIC-3 ON THE EXPRESSION PROFILE OF SEROTONIN TYPE 3A RECEPTORS. Lauretta Anne Pierre , Hoa Quynh Do, Nermina Sarayli Belirgen, Michaela Jansen

1194-pos Board B323 VIRTUAL SCREENING (VS) BASED IN THE COMMON BINDING SITE FOR NEGATIVELY CHARGED ACTIVATORS OF K + CHANNELS. A COMPARISON WITH A PHARMACOPHORE-BASED VS. Wendy Gonzalez , Marcelo Araneda, Estanislao Marquez, Fernando Vergara, Han Sun, Niels Decher 1195-pos Board B324 VOLTAGE SENSITIVE ION CHANNELS, MINIMAL SIZE OF ORDERED PHASES AND THE EVOLUTION OF METAZOA. H. Richard Leuchtag 1196-pos Board B325 INTRODUCING ELECTROSTATIC STIMULATION TO NORMAL MODE ANALYSIS. Alexandre Beaulac, Olivier Malihot, Rafael Najmanovich, Rikard Blunck Ligand-Gated Channels I (Boards B326 - B350) 1197-pos Board B326 Travel Award Winner RECONSTRUCTING IDENTICAL AGONIST SITES IN THE MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEPTOR. Johnathon R. Emlaw , Corrie J.B. daCosta 1198-pos Board B327 INSIGHTS INTO THE DESENSITIZATION MECHANISMS OF ACID-SENSING ION CHANNELS. Caroline Marcher Holm , Stephanie A. Heusser, Asli B. Topaktas, Stephan A. Pless 1199-pos Board B328 FMRFAMIDE-GATED SODIUM CHANNEL DIVERSITY RELATIONSHIP TO OTHER DEG/ENAC CHANNELS, AND THE MOLECULAR BASIS FOR NEUROPEPTIDE ACTIVITY. Mowgli Dandamudi , Harald Hausen, Timothy Lynagh 1200-pos Board B329 DUPLICATED BINDING SITE FOR RIC-3 CHAPERON PROTEIN IN SERO TONIN TYPE 3A SUBUNITS. Hoa Quynh Do , Michaela Jansen 1201-pos Board B330 AGONIST EFFICIENCY IN A NICOTINIC RECEPTOR. Dinesh Indurthi, Anthony Auerbach 1202-pos Board B331 STRUCTURAL BASIS FOR THE REGULATION MECHANISM OF CA 2+ - DEPENDENT ACTIVITY OF TMEM16 SCRAMBLASE. Zhang Feng , Omar E. Alvarenga-Cruz, Alessio Accardi 1203-pos Board B332 USING CGMP ANALOGUES TO MODULATE PHOTORECEPTOR LIGHT SEN SITIVITY. Sophie Wucherpfennig, Wadood Haq, Valerie Popp, Sandeep Kesh, Frank Schwede, Francois Paquet-Durand, Vasilica Nache 1204-pos Board B333 Travel Award Winner ANCESTRAL ACETYLCHOLINE RECEPTOR BETA-SUBUNIT FORMS HOMO PENTAMERS THAT PRIME BEFORE OPENING SPONTANEOUSLY. Christian Tessier , Raymond M. Sturgeon, Johnathon Emlaw, Gregory McCluskey, F Javier Pérez-Areales, Corrie J.B. daCosta 1205-pos Board B334 CONFORMATIONAL DYNAMICS OF THE CYTOPLASMIC CAP DURING DESENSITIZATION OF THE HP2X3R. Linhan Cheng , Saskia Cönen, Ralf Hausmann, J.-P. Machtens 1206-pos Board B335 STRUCTURAL CHARACTERIZATION OF PH- AND CALCIUM-MODULATED OPEN AND CLOSED STATES OF THE PENTAMERIC LIGAND-GATED ION CHANNEL DECLIC. Olivia Andén , Urska Rovsnik, Marie Lycksell, Marc H. Delarue, Rebecca J. Howard, Erik R. Lindahl

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