Biophysical Society 67th Annual Meeting Program Guide

1485-Symp 11:45 am MITOCHONDRIAL UNCOUPLERS INDUCE PROTON LEAK BY ACTIVATING AAC AND UCP1. Ambre Bertholet , Andrew Natale, Paola Bisignano, Junji Suzuki, Andriy Fedorenko, James Hamilton, Tatiana Brustovetsky, Lawrence Kazak, Edward T. Chouchani, Nickolay Brustovetsky, Michael Grabe, Yuriy V. Kirichok 1486-Symp 12:15 pm STRUCTURAL BASIS FOR PROTON COUPLED CYSTINE TRANSPORT BY CYSTINOSIN. Simon Newstead Symposium Best of Biophysical Journal : From Single Molecules to Systems 10:45 am - 12:45 pm, Room 6C Chair Vasanthi Jayaraman, University of Texas Health Science Center at Hous ton, USA No Abstract 10:45 am DISTRIBUTION OF CHOLESTEROL IN ASYMMETRIC MEMBRANES DRIVEN BY COMPOSITION AND DIFFERENTIAL STRESS. Markus Deserno No Abstract 11:15 am DECIPHERING THE MOLECULAR ORGANIZATION OF GET PATHWAY CHAP ERONES THROUGH NATIVE MASS SPECTROMETRY. Kallol Gupta No Abstract 11:25 am AN OPEN STATE OF A VOLTAGE-GATED SODIUM CHANNEL INVOLVING A Π-HELIX AND CONSERVED PORE-FACING ASPARAGINE. Rebecca J. Howard No Abstract 11:45 am EFFECTS OF CLOT CONTRACTION ON CLOT DEGRADATION: A MATH EMATICAL AND EXPERIMENTAL APPROACH. Valerie Tutwiler No Abstract 12:05pm RAPID EXTRACTION AND KINETIC ANALYSIS OF PROTEIN COMPLEXES FROM SINGLE CELLS. Daniel J. Dickinson No Abstract 12:25pm Paper of the Year-Early Career Investigator Award PRECISION IN ITERATIVE MODULATION ENHANCED SINGLE-MOLECULE LOCALIZATION MICROSCOPY. Carlas S. Smith Platform Chromatin and the Nucleoid 10:45 am - 12:45 pm, Room 6D Co-Chairs Alberto Marin-Gonzalez, Johns Hopkins University, USA Lauren McCarthy, University of Michigan, USA 1487-Plat 10:45 am HIGH-CONTENT IMAGE-BASED CRISPR SCREENING REVEALS REGULA TORS OF 3D GENOME ARCHITECTURES. Bing Yang, Mengwei Hu, Tyler Jensen, Jonathan Radda, Yubao Cheng, Shengyan Jin, Siyuan Wang 1488-Plat 11:00 am THE CHROMATIN REMODELER ISWI REGULATES CHROMATIN MOBILITY IN AN ATP-DEPENDENT MANNER. Petra Vizjak, Dieter Kamp, Johannes Stigler , Felix Mueller-Planitz 1489-Plat 11:15 am POLYMER MODEL PREDICTS HISTORY DEPENDENT EPIGENETIC AND LAMIN-ASSOCIATED DOMAIN SIZES. Vinayak Vinayak , Ramin Basir, Lucas Sant’Anna, Vivek B. Shenoy 1490-Plat 11:30 am Travel Award Winner MULTIPLEXING CAS9 ACTIVITY WITH MULTI-TARGET CRISPR. Alberto Marin-Gonzalez , Roger Zou, Yang Liu, Leo Shen, Rachel Dveirin, Jay Luo, Reza Kalhor, Taekjip Ha

sion, far away from the coverslip. In STORM and PALM, a laser switches dye molecules actively on and off. Special imaging buffers create a similar blinking spontaneously in dSTORM. DNA-PAINT relies on oligonucle otides’ transient binding, and genomic applications use sparse labeling and multiplexing. In this presentation, we will discuss how the Bruker Vutara VXL compact bench-top system brings the power of SMLM into your lab. Speaker Winfried Wiegraebe, Product Manager Superresolution Microscopy, Bruker Exhibits 10:00 am - 4:00 pm, Exhibit Hall BC Take this opportunity to meet editors of the Society’s newest journal, Biophysical Reports . Editors will be available to talk about the journal and answer questions about where you should submit your work, what will help to get your work published, and what you can expect when you submit. Editor-in-Chief Jörg Enderlein and other editors will be present at the Biophysical Society booth. Coffee Break 10:15 am - 11:00 am, Exhibit Hall BC Symposium Viral Recognition, Entry, and Egress 10:45 am - 12:45 pm, Room 6A Chair James Munro, University of Massachusetts, USA 1481-Symp 10:45 am HERPESVIRUSES DEFORMMEMBRANE DURING CAPSID NUCLEAR EXPORT BY LIPID ORDERING AND PROTEIN SCAFFOLDING. Ekaterina Heldwein 1482-Symp 11:15 am DISSECTING HOST/PATHOGEN INTERACTIONS IN THE GASTROINTESTINAL EPITHELIUM. Megan L. Stanifer 1483-Symp 11:45 am STRUCTURE, FUNCTION AND DYNAMICS OF ALPHAVIRUS CAPPING PORES. Rhian Jones, Michael Hons, Nadia Rabah, Noelia Zamarreno Fernandez, Rocio Arranz Avila, Juan Reguera 1484-Symp 12:15 pm CONFORMATIONAL DYNAMICS OF VIRAL FUSION PROTEINS AT SINGLE MOLECULE RESOLUTION. Natasha D. Durham, Aastha Jain, James B. Munro Symposium Proton Coupled Transport in Organelles 10:45 am - 12:45 pm, Room 6B Chair Simon Newstead, University of Oxford, United Kingdom No Abstract 10:45 am LIPID MODULATION YIELDS INSIGHTS INTO CLC-7 GATING MECHANISMS. Joseph Mindell No Abstract 11:15 am ENDOSOMES AS A SIGNALING HUB: THE ROLE OF NHE TRANSPORTERS. Rajini Rao Meet the Editors, Biophysical Reports 10:15 am - 11:00 am, Lobby BC/Publications Booth

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