Biophysical Society 67th Annual Meeting Program Guide

1664-Pos Board B69 BINDING OF E. COLI SINGLE-STRANDED DNA BINDING PROTEIN TO DAM AGED DNA SUBSTRATES MEASURED AT SINGLE MOLECULE LEVEL USING AFM. Francesco C. Navarro Roby 1665-Pos Board B70 FORK REGRESSION VISUALIZATION USING SINGLE-MOLECULE FRET. Penelope Romo , Rajen Goutam, Danielle R. Latham, Hugo Sanabria, Coby Bowman, Inna Yanez Membrane Protein Folding (Boards B71 - B82) 1666-Pos Board B71 Travel Award Winner MECHANISMS BY WHICH WATER-MEDIATED HYDROGEN-BOND NET WORKS GOVERN PH-DEPENDENT REACTIONS AT MEMBRANE INTERFAC ES. Eva Bertalan, Honey Ashok A. Jain, Kalina Hristova, William C. Wimley, Ana-Nicoleta Bondar 1667-Pos Board B72 PARKINSON’S DISEASE-ASSOCIATED MUTANTS SHIFT EQUILIBRIUM BOUND STATE OF ALPHA-SYNUCLEIN TOWARDS THE SECOND HELIX. Sofiya Maltseva , Daniel H. Kerr, Miah J. Turke, Ka Yee C. Lee 1668-Pos Board B73 THE DEPENDENCY OF SLOW CLC-EC1 DIMERIZATION KINETICS ON LIPID SOLVENT VOLUME. Taeho Lee , Rahul Chadda, Tugba N. Ozturk, Robyn Mahoney-Kruszka, Janice L. Robertson 1669-Pos Board B74 THE ROLE OF PROTEIN-PROTEIN INTERACTIONS IN FLUC DIMERIZA TION STABILITY AND FUNCTION. Melanie Ernst , Jennifer Chen, Janice L. Travel Award Winner THE ROLE OF LIPID BILAYER COMPOSITION IN CELL-FREE EXPRESSED ABC TRANSPORTER FOLDING. Citlayi G. Villaseñor , Valentina Dimitrova, Alexandra Karagiaridi, Kristen Rivera, Heather Pinkett, Neha P. Kamat 1671-Pos Board B76 USING HDX-MS TO PROBE THE DYNAMICS AND DENATURED STATE OF GLPG, A HELICAL MEMBRANE PROTEIN. Abigail L. Schroeter , Saba Kan wal, Heedeok Hong, Tobin R. Sosnick 1672-Pos Board B77 EFFECTS OF NATURAL PRODUCTS ON CYSTIC ACTIVITY IN KIDNEY CELLS. Jorge A. Hurtado Camacho , Marshall Gilmer, Justus Gabriel, Tristan McKenzie, Claire M. Hsu, Martin Park, Ryan Limbocker 1673-Pos Board B78 REGULATION OF THE BACTERIAL TRANSLOCON SECYEG BY PERIPLAS MIC PH. Denis G. Knyazev , Nora Hagleitner-Ertugrul, Laura Nübl, Janin Simader, Nikolaus Gössweiner-Mohr, Christine Siligan, Peter Pohl 1674-Pos Board B79 THE DELIVERY COMPLEX IN OUTER MEMBRANE PROTEIN BIOGENESIS: HOW THE SURA CHAPERONE INTERACTS WITH THE BAM ENZYME. Jim E. Horne , Katherine Fenn, Joel A. Crossley, Sheena E. Radford, Neil A. Ranson 1675-Pos Board B80 INTERACTIONS OF Β-BARREL ASSEMBLY MACHINERY PROTEIN D (BAMD) WITH PHOSPHOLIPID BILAYERS. Ly Nguyen, Joerg H. Kleinschmidt 1676-Pos Board B81 CAN A SIMPLE AND GENERALIZABLE ASSAY DISTINGUISH BETWEEN MU TANT PHENOTYPES OF MODEL MEMBRANE PROTEINS? Henry Gatica Gutierrez Robertson 1670-Pos Board B75

1649-Pos Board B54 DESIGNING BCL-2 PROTEIN BINDING APTAMERS USING AN ENTROPIC FRAGMENT-BASED APPROACH & IN VITRO VALIDATE THE DRUG EFFICA CY. Fatimah M. Alharbi , Nayyar Rabbani, Chih-Yuan Tseng, Jack Tuszynski, Md Ashrafuzzaman 1650-Pos Board B55 BLOCKING HUNTINGTIN OLIGOMERS FROM BINDING LIPID MEMBRANES IMPROVES PHENOTYPE IN A C.ELEGANS MODEL OF HUNTINGTON’S DISEASE. Chathuranga Siriwardhana , Justin A. Legleiter 1651-Pos Board B56 REGIOSELECTIVE METABOLISM OF CANNABINOIDS BY CYTOCHROME P450 2J2. Hale S. Hasdemir , Pritam Roy, Aditi Das, Emad Tajkhorshid 1652-Pos Board B57 BANDAIDS ON BROKEN HEARTS: PREVENTING PROTEASE-MEDIATED DEGRADATION OF DESMOPLAKIN WITH SMALL MOLECULES. Roujon A. Nowzari , Isabel M. Romov, Nathan T. Wright 1653-Pos Board B58 QUALITY CONTROL OF FLUORESCENCE POLARIZATION ASSAY OVER GEL BASED ASSAY. Clay P. Page 1654-Pos Board B59 PROTEIN - LIGAND BINDING AFFINITY BY DIFFERENTIAL SCANNING CALO RIMETRY. Daumantas Matulis , Asta Zubriene, Vaida Linkuviene 1655-Pos Board B60 SOLID-STATE NMR SPECTROSCOPY UNCOVERS INTERNAL DYNAMICS OF ANTIVIRAL COMPOUNDS. Ankan Nath , Soohyun Lee, Trivikram R. Molugu, Jun Wang, Andrey V. Struts, Michael F. Brown 1656-Pos Board B61 INHIBITION OF THE SARS-COV-2 MAIN PROTEASE BY A THIADIAZOLIDI NONE DERIVATIVE. Katarina Jovic , Logan Brown, Harish Vashisth, Krisz tina Varga 1657-Pos Board B62 NATURAL EFFECTORS FOR CONFORMATIONAL CONTROL OF CORONAVI RUS SPIKE PROTEINS. Daniel Asarnow , David Veesler 1658-Pos Board B63 USE OF COMPLEMENTARY BIOPHYSICAL METHODS TO CHARACTERIZE LIGAND BINDING TO IL-17A. Parag Sahasrabudhe , Shenping Liu 1659-Pos Board B64 PROBING PROTEIN-KETONE BODY INTERACTION TO ELUCIDATE THE FUNCTION OF PUTATIVE ABC TRANSPORTERS. Bryant J. Kane , Junko Okuda-Shimazaki, Koji Sode 1660-Pos Board B65 MECHANISM OF SLOW HERG1 CHANNEL DEACTIVATION INDUCED BY RPR260243. Eva-Maria Plessl , Michael C. Sanguinetti, Anna Stary-Weinz inger 1661-Pos Board B66 TUNING THE SIZE AND SOLVENT-EXPOSED HYDROPHOBICITY OF A PORE FORMING PEPTIDE ELIMINATES ITS CYTOTOXICITY USING A NATURAL PRODUCT. Justus M. Gabriel , Thomas Tan, Claire M. Hsu, Caleb Buettner, Ryan Limbocker 1662-Pos Board B67 EXOGENOUS LIGAND BINDING KINETICS OF GLOBIN X. Jonathan Cedeno Lugo , Jaroslava Miksovska, Sophie Bernad, Valerie Derrien 1663-Pos Board B68 GLOBIN X: A TARGET FOR SURFACTANT-LIKE MOLECULES. Rifat Farhana , Valerie Derrien, Sophie Bernad, Jaroslava Miksovska

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