Biophysical Society 67th Annual Meeting Program Guide

Protein Aggregates (Boards B107 - B129) 1702-Pos Board B107 TRANSIENT OLIGOMERIZATION CAUSING PROTEINOPATHIES. Grace E. Orellana , Ellinor Haglund 1703-Pos Board B108 STUDIES OF SELECTED CARBON NANOMATERIALS WITH AMYLOID BETA PEPTIDES. Anna Bisok , Marietta Koźlarek, Anna Burwiel, Julia Telus, Joanna M. Wolak, Żaneta Polańska, Maciej Kozak 1704-Pos Board B109 PROBING THE MORPHOLOGICAL AND MECHANICAL CHANGES IN A C. EL EGANS MODEL OF HUNTINGTON’S DISEASE. Zachary L. Ellis , Chathuranga C. Siriwardhana, Justin A. Legleiter 1705-Pos Board B110 ROLE OF N17’S HYDROPHOBIC FACE IN MEMBRANE CURVATURE SENS ING AND POLYQ AGGREGATION. Neha Nanajkar , Abhilash Sahoo, Silvina Board B111 MEMBRANE PROTEIN CHAPERONE AFFECTS THE KINETICS AND MOR PHOLOGY OF AMYLOID BETA AGGREGATION. Hunter T. Ordner 1707-Pos Board B112 AΒ PROTEIN GROWTH MONITORING BY STRUCTURE-SPECIFIC LABEL FREE THZ SPECTROSCOPY. Chaejeong Heo 1708-Pos Board B113 COMPARING THE STRUCTURE AND STABILITY OF DIVERSE AMYLOID BETA OLIGOMERS USING FLUORESCENCE CORRELATION SPECTROSCOPY. Kamila Nurmakova , Zachary Levine 1709-Pos Board B114 INHIBITION STUDIES ON AGGREGATION AND CYTOTOXICITY OF ALZHEIM ER’S AMYLOID-Β PEPTIDE. Nikoletta Murvai , Yuxi Lin, Tamás Molnár, Attila Kovács, András Micsonai, Jeong Kyu Bang, Young-Ho Lee, Jozsef Kardos 1710-Pos Board B115 Travel Award Winner DETECTING PHYSIOLOGICAL CONCENTRATIONS OF ALZHEIMER’S ASSOCI ATED AMYLOID-Β OLIGOMERS WITH A CELL-BASED RESPONSE. Brittany Board B116 ASSESSING P53 AGGREGATES OVER A LIFETIME: STUDIES ON YOUNG, ADULT, AND AGED MICE. Matthew Steinsaltz , Zachary A. Levine 1712-Pos Board B117 MUTATIONS AFFECT THE CONFORMATIONAL PLASTICITY OF THE Β2-Α2 LOOP OF HUMAN PRION PROTEIN. Aliciarose John, David Kemper, Pedro Fernandez-Funez, Alessandro Cembran 1713-Pos Board B118 Travel Award Winner ANALYSIS AND COMPARISON OF AMORPHOUS & AMYLOID AGGREGATES OF THE TUMOR SUPPRESSOR P53. Emi Hibino , Takeshi Tenno, Hidekazu Hiroaki 1714-Pos Board B119 STRUCTURAL FLEXIBILITY OF HUNTINGTIN OLIGOMERS PLAYS A KEY ROLE IN DIRECTLY BINDING LIPID MEMBRANES. Justin A. Legleiter 1715-Pos Board B120 MICRO-FLOW IMAGING AND FLOW VIROMETRY AS PREFERRED METH ODS TO MONITOR PARTICULATE MATTER FOR A HUMAN CYTOMEGALO VIRUS VACCINE CANDIDATE. Ashley L. Hardy 1716-Pos Board B121 INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON PROTEIN CLUSTERING: IMPLICATIONS FOR PROCESSING AND MACROSCOPIC CRYSTALLIZA TION. Brian Paul , Susana Cristina Marujo Teixeira, Eric M. Furst, Abraham M. Lenhoff, Norman Wagner Matysiak 1706-Pos E. Watson 1711-Pos

1717-Pos Board B122 DIFFERENTIAL BINDING DYNAMICS OF FOUR MICROTUBULE-BINDING REPEATS OF TAU WITH AN AMYLOID-Β FIBRIL SEED. Zhiyuan Song , Feng Ding, Yunxiang Sun 1718-Pos Board B123 PROBING REGULATORY MECHANISMS OF THE DE NOVO DNA METHYL TRANSFERASE DNMT3A. Emma M. Garcia , Nicholas Z. Lue, Keith Rivera, Maya Virshup, Jessica K. Liang, Derek D. Hwang, Steven A. Carr, Brian B. Liau 1719-Pos Board B124 PEPTIDE-BASED INHIBITORS OF AMYLOID BETA AGGREGATION AND TOX ICITY. Maria Zabala Rodriguez , Ken Teter, Suren Tatulian 1720-Pos Board B125 Travel Award Winner PEPTOIDS AS POTENTIAL THERAPEUTICS TO REDUCE S100B-INDUCED RAGE-ASSOCIATED NEUROINFLAMMATION IN ALZHEIMER’S DISEASE. Mihyun L. Waugh , Shannon Servoss, Melissa A. Moss 1721-Pos Board B126 COFACTOR-DEPENDENT STRUCTURAL TRANSITION OF SOD1 MODULATES ITS ABILITY TO UNDERGO LIQUID-LIQUID PHASE SEPARATION. Sumangal Roychowdhury , Bidisa Das, Priyesh Mohanty, Azamat Rizuan, Jeetain Mit tal, Krishnananda Chattopadhyay 1722-Pos Board B127 DIRECT OBSERVATION OF SINGLE-MOLECULAR HIAPP FIBRIL ELONGA TION REVEAL MOLECULAR MECHANISMS OF MORPHOLOGICAL DEPEN DENCE AND ASYMMETRIC GROWTH. Gangtong Huang , Feng Ding 1723-Pos Board B128 POLYGLUTAMINE CORE IS THE PRIMARY DRIVER OF SEEDED HUNTINGTIN AGGREGATION. Adam Skeens , Justin A. Legleiter 1724-Pos Board B129 NANOSCALE INFRARED SPECTROSCOPY IDENTIFIES STRUCTURAL EVO LUTION OF AΒ 16-22 FIBRILS FROM PARALLEL TO ANTIPARALLEL BETA SHEETS. Divya Lnu , Siddhartha Banerjee, Ayanjeet Ghosh Poster: DNA Replication, Recombination, and Repair (Boards B130 - B142) 1725-Pos Board B130 HUMAN XPD IS AN ACTIVE HELICASE WITH LOW PROCESSIVITY AND OVERALL UNWINDING RATE. Chunfeng Mao, K. Maria Mills 1726-Pos Board B131 SINGLE-MOLECULE STUDIES REVEAL THAT MUTS’S BINDING CHARACTER ISTICS ARE MISMATCH TYPE AND CONTEXT DEPENDENT AND CORRE LATE WITH MISMATCH REPAIR EFFICIENCY IN VIVO . Jasmin Zarb , James London, Richard Fishel, Taekjip Ha 1727-Pos Board B132 Travel Award Winner SINGLE-MOLECULE DYNAMICS OF RIBONUCLEASE H ENZYMES IN BACIL LUS SUBTILIS . Jewel Ashbrook , Ziyuan Chen, Julianna Cresti, Lyle A. Sim mons, Julie Biteen 1728-Pos Board B133 A BIOCHEMISTRY PLATFORM TO INCORPORATE REPLICATION FORKS, DNA LESIONS, AND NUCLEOSOME ARRAYS TO SINGLE-MOLECULE EXPERI MENTS. Trey Simpson , Marco Simonetta, Mattijs de Groot, Bas Groen 1729-Pos Board B134 Travel Award Winner MTB UVRD1 MONOMER UNWINDS A KU NUCLEOPROTEIN FILA MENT. Ankita Chadda , Eric A. Galburt

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