Biophysical Society 67th Annual Meeting Program Guide

1888-Pos Board B293 REKINDLE THERAPEUTIC STRATEGIES FOR LONG QT SYNDROME FROM GAIN OF FUNCTION (IKR) MUTATIONS IN HERG. Amit Kumawat , Carlo Board B294 NON-STATIONARY NOISE ANALYSIS OF WHOLE-CELL CURRENTS FROM CHO HERG EXPRESSION SYSTEMS. Alejandra Donaji Herrera Reyes , Gary Board B295 RESTORING THE FUNCTION OF HERG LQT2 N-TERMINAL MUTANTS WITH NON-CANONICAL AMINO ACIDS. Ileana Raquel Hernandez Araiza , Matt C. Trudeau 1891-Pos Board B296 Travel Award Winner DETERMINING THE ROLE OF THE UNIQUE N-TERMINAL 1B DOMAIN IN THE GATING OF HETEROTETRAMERIC HERG1A/HERG1B POTASSIUM CHANNELS. Taylor R. Crawford , Matt C. Trudeau 1892-Pos Board B297 Travel Award Winner USING THE PHOTO-CROSSLINKABLE NON-CANONICAL AMINO ACID BZF TO CAPTURE U.V.-DRIVEN, STATE-DEPENDENT DISRUPTION OF KINETICS AND VOLTAGE DEPENDENCE OF ACTIVATION IN HERG POTASSIUM CHAN NELS. Sara J. Codding , Gail A. Robertson, Matt C. Trudeau 1893-Pos Board B298 A POSSIBLE ROLE FOR PHASE SEPARATION IN HETEROMERIC BIOGENESIS OF HERG1A/1B CHANNELS. Sudharsan Kannan , Peter Luong, William Kasberg, Anjon Audhya, Gail A. Robertson 1894-Pos Board B299 SPECIFIC INTERACTIONS CRITICAL FOR THE GATING OF HCN CHAN NELS. Kevin P. Cunningham , Xiaoan Wu, Marta E. Perez, Peter H. Larsson 1895-Pos Board B300 DESIGN OF A PHOTO-ACTIVATABLE IVABRADINE TO ENABLE LIGHT IN DUCED BLOCK OF HCN CURRENT IN TISSUES. Alessandro Porro , Cristiano Bolchi, Federico Brandalise, Rebecca Appiani, Roberta Leone, Federico Thei, Gerhard Thiel, Marco Pallavicini, Anna Moroni 1896-Pos Board B301 S5-S6 INTERACTIONS IMPORTANT FOR THE ELECTROMECHANICAL COUPLING IN HCN CHANNELS. Xiaoan Wu , Kevin P. Cunningham, Marta E. Perez, Peter H. Larsson 1897-Pos Board B302 MEMBRANE PHOSPHOLIPIDS INDUCE MODERATE POSITIVE COOPERA TIVITY IN CLOSED PACEMAKER CHANNELS. Vinay Idikuda , SUSOVAN ROY CHOWDHURY, Randall H. Goldsmith, Baron Chanda Ligand-Gated Channels II (Boards B303 - B325) 1898-Pos Board B303 EXPLORING THE EFFECTS OF NANODISCS ON THE CONFORMATION OF A PENTAMERIC LIGAND-GATED ION CHANNEL. Mark J. Arcario , Vikram Dalal, Grace H. Brannigan, Wayland W. Cheng 1899-Pos Board B304 MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEPTOR STRUCTURE, FUNC TION, AND PHARMACOLOGY. Umang Goswami , Md Mahfuzur Rahman, Jinfeng Teng, Ryan E. Hibbs 1900-Pos Board B305 A NOVEL APPROACH TO DISSECT IONS OCCUPANCY AND DISSOCIATION CONSTANT OF INDIVIDUAL BINDING SITES WITHIN THE K + -CHANNEL SELECTIVITY FILTER. Megan M. Skains , D. Marien Cortes, Luis G. Cuello Camilloni 1889-Pos R. Mirams 1890-Pos

1901-Pos Board B306 STATE-DEPENDENT SALT BRIDGE INTERACTION DURING ACTIVATION IN PROKARYOTIC CYCLIC NUCLEOTIDE-GATED CHANNEL STHK. Pierce Eggan , Eric Evans, William N. Zagotta 1902-Pos Board B307 IDENTIFICATION AND CHARACTERISATION OF LIPIDS THAT ARE POSITIVE ALLOSTERIC MODULATORS OF GLYCINE RECEPTORS. Casey I. Gallagher, Yie Chang Lin, Arvind Kumar, Damian Ha, Christopher L. Cioffi, Sudha Chakrapani, Megan L. O’Mara, Robert J. Vandenberg 1903-Pos Board B308 STRUCTURAL BASIS FOR THE ALLOSTERIC MODULATION OF GABA A RECEPTORS BY NEUROSTEROIDS. Ayobami Diyaolu , Peter Obi, Pavan Payghan, Senthil Natesan 1904-Pos Board B309 OXIDATION DRIVEN REVERSAL OF PIP 2 -DEPENDENT GATING IN GIRK2 CHANNELS. Sun Joo Lee , Shoji Maeda, Colin G. Nichols 1905-Pos Board B310 THE MOLECULAR MECHANISM OF SNAKE SHORT-CHAIN ALPHA-NEURO TOXIN BINDING TO MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEP TORS. Mieke Nys, Eleftherios Zarkadas, Marijke Brams, Aujan Mehregan, Kumiko Kambara, Jeroen Kool, Nicholas Casewell, Daniel Bertrand, John E. Baenziger, Hugues Nury, Chris Ulens 1906-Pos Board B311 Travel Award Winner SILICA NANOPARTICLES INHIBIT RESPONSES TO ATP IN HUMAN AIRWAY EPITHELIAL 16HBE CELLS. Alina Milici , Karel Talavera, Alicia Sanchez Linde 1907-Pos Board B312 ION PERMEATION PATHWAY WITHIN THE INTERNAL PORE OF P2X RECEP TOR CHANNELS. Stephanie W. Tam , Katherine Huffer, Mufeng Li, Kenton Swartz 1908-Pos Board B313 CELL DEATH IN ISOLATED XENOPUS LAEVIS (AFRICAN CLAWED FROG) OOCYTES IS A TEMPERATURE-DEPENDENT PROCESS. Nils Otten , Michael Hollmann, Horst Lohmann 1909-Pos Board B314 MODULATION OF A LIGAND-GATED ION CHANNEL BY AN AMPHETAMINE DERIVATIVE. Emelia Karlsson , Olivia Andén, Marc H. Delarue, Rebecca J. Howard, Erik R. Lindahl 1910-Pos Board B315 CBD SPECIFIC ACTION ON GABA A RECEPTOR ALPHA SUBUNITS. Ashley Davies , Ali Yehia, Charlotte Caddick, Nathan Hunt, Tommaso Iannitti 1911-Pos Board B316 Travel Award Winner REVEALING THE ARRANGEMENT OF THE INTRACELLULAR TERMINI OF ASIC1A USING TRANSITION METAL ION FRET. Megan Cullinan , John Board B317 CHARGED RESIDUES IN THE GABA-A RECEPTOR INTRACELLULAR DOMAIN IMPACT CHANNEL ACTIVATION AND DESENSITIZATION. John C.I. Merrick , Cynthia Czajkowski, Anton J. Tung 1913-Pos Board B318 FLUORESCENT, NON-HYDROLYZABLE NUCLEOTIDE PROBES FOR ATP ACTIVATED ION CHANNELS. Christina Alcaro , Priscilla Rubio, Michael C. Puljung 1914-Pos Board B319 STRUCTURAL AND EVOLUTIONARY STUDIES ON CEPHALOPOD CHEMO TACTILE RECEPTORS. Guipeun Kang , Corey Allard, Wendy Valencia-Mon toya, Jeong Joo Kim, Lena van Giesen, Peter Kilian, Xiaochen Bai, Nicholas Bellono, Ryan E. Hibbs Bankston 1912-Pos

T U

E S

D A Y

119