Biophysical Society 67th Annual Meeting Program Guide

1915-Pos Board B320 COMPUTATIONAL ANALYSIS OF INTERACTIONS BETWEEN AMPA RECEP TOR AND CON-IKOT-IKOT CONOTOXIN. Natalia A. Szlachetka , Christo pher W. Wood, Jelena Baranovic 1916-Pos Board B321 USING FLUORESCENCE TO MEASURE REAL-TIME BINDING OF SERO TONIN TO ITS RECEPTORS. Aspen Hawkins , Olivia Brado, Michael C. Puljung 1917-Pos Board B322 PENTAMERIC LIGAND GATED ION CHANNELS’ INTRACELLULAR DOMAIN INTERACTION WITH RIC3 CHAPERONE. Nermina Sarayli Belirgen , Hoa Quynh Do, Austin D. Rodgers, Lauretta Anne Pierre, Irina Kim Cavdar, Michaela Jansen 1918-Pos Board B323 MOLECULAR DYNAMICS SIMULATIONS OF NEURONAL NICOTINIC ACE TYLCHOLINE RECEPTOR ALLOSTERIC MODULATION. Cristian Sales Garcia, Cynthia Hu, Elle Albrecht, Yuxuan Zhuang, Rebecca J. Howard, Erik R. Lindahl, Mark M. Levandoski 1919-Pos Board B324 Travel Award Winner MECHANISTIC INSIGHTS INTO LIPID REGULATION OF THE ACID-SENSING ION CHANNELS. Robert C. Klipp , John R. Bankston 1920-Pos Board B325 A SYNTHETIC APPROACH TO YUGO K + CHANNEL BIOPHYSICS. Megan Larmore , Orhi Esarte Polomero, Neha P. Kamat, Paul G. DeCaen 1921-Pos Board B326 EXAMINING THE EFFECT OF A SUBSTITUTED CARBAMATE POSITIVE ALLOSTERIC MODULATOR ON THE (Α4)3(Β2)2 AND (Α4)2(Β2)3 NICO TINIC ACETYLCHOLINE RECEPTORS. Josue Gaona , Musharaf Mohiuddin, Ayman K. Hamouda 1922-Pos Board B327 CYTOTOXICITY AND INTERNALIZATION PROPERTIES OF NOVEL ALPHA7 NICOTINIC RECEPTOR SELECTIVE PEPTIDES. Lahra Weber , Brittany C.V. OBrien, Maegan M. Weltzin 1923-Pos Board B328 DESIGN AND OPTIMIZATION OF NICOTINIC ACETYLCHOLINE RECEP TOR SUBTYPE SELECTIVE PEPTIDES. Brittany C.V. OBrien , Lahra Weber, Maegan M. Weltzin 1924-Pos Board B329 SUBTYPE-SPECIFIC POTENTIATION OF OTOPETRIN PROTON CHANNELS BY ZN 2+ AND ITS STRUCTURAL BASIS. Joshua P. Kaplan , Bochuan Teng, Marcel P. Goldschen-Ohm, Emily R. Liman 1925-Pos Board B330 Travel Award Winner KINETIC MECHANISM OF NMDA RECEPTOR INHIBITION BY THE KET AMINE METABOLITE 2R,6R-HYDROXYNORKETAMINE. Faye Raymond 1926-Pos Board B331 NOVEL SMALL-MOLECULE MODULATION OF PIEZO1 INVESTIGATED BY CONVENTIONAL AND AUTOMATED PATCH-CLAMP. Jacob A. Kinsella , Gregory Parsonage, Oleksandr V. Povstyan, Nicoletta Murciano, Rachel Trowbridge, Charlotte Revill, Adam Nelson, Maria Giustina Rotordam, Nadine Becker, Andrea Bruggemann, Richard Foster, David J. Beech 1927-Pos Board B332 RATIONALE DESIGN OF NOVEL PIEZO1 MODULATORS. Wenjuan Jiang, Tharaka D. Wijerathne, Han Zhang, Yi-Chun Lin, Wonpil Im, Jerome J. Lacroix , Yun Lyna Luo Ion Channels, Pharmacology, and Disease II (Boards B326 - B334)

1928-Pos Board B333 THE SODIUM LEAK COMPLEX AND FRIENDS: IDENTIFYING PROTEIN PARTNERS OF THE NALCN CHANNELOSOME. Samuel Usher , Stephan A. Pless 1929-Pos Board B334 PARACELLULAR ION TRANSPORT IN CLAUDIN-15 ION CHANNELS. Sarah McGuinness , Sukanya Konar, Shadi Fuladi, Fatemeh Khalili-Araghi Membrane Pumps, Transporters, and Exchangers I (Boards B335 - B353) 1930-Pos Board B335 THE EFFECTS OF DISEASE-CAUSING CLC-7 MUTATIONS ON LYSOSOMAL PH. Vedrana Mikusevic , Jacob K. Hilton, Reena Jethva, Joseph A. Mindell 1931-Pos Board B336 MECHANISM OF CLC-7 TRANSPORTER INHIBITION BY THE LYSOSOMAL PHOSPHOLIPID PI(3,5)P2. Jacob K. Hilton , Joseph A. Mindell 1932-Pos Board B337 MOLECULAR DYNAMICS CHARACTERIZATION OF THE MECHANISM OF INHIBITION OF CLC-7 ACTIVITY BY PI(3)P. Eric Sefah , Jacob K. Hilton, Joseph A. Mindell, Michael Grabe 1933-Pos Board B338 THE HOMOLOGY OF ELEVATOR AND ROCKING BUNDLE TRANSPORT ERS. Noah Trebesch , Emad Tajkhorshid 1934-Pos Board B339 INVESTIGATION OF CONFORMATIONAL SAMPLING OF LEUT DUE TO NA SITE MUTATIONS AT THR 354 AND SER 355 WITH DEER EPR SPECTROS COPY. Brynn E. Elson , Kelli N. Kazmier, Richard A. Stein 1935-Pos Board B340 THE MOLECULAR PUZZLE OF THE HUMAN SEROTONIN TRANSPORTER: WHERE A PROTON AND A POTASSIUM FIT IN THE PICTURE. Eva Hellsberg , Danila Boytsov, Walter Sandtner, Lucy R. Forrest 1936-Pos Board B341 INVESTIGATION OF THE TRANSPORT CYCLE OF SODIUM GLUCOSE TRANSPORT PROTEINS THROUGH COMPUTATIONAL SIMULATION. Fiona B. Naughton , John M. Rosenberg, Michael Grabe 1937-Pos Board B342 AN ELECTROPHYSIOLOGICAL APPROACH FOR LOW TURNOVER AND IN TRACELLULAR TRANSPORT PROTEINS: IMPROVING AMPLIFICATION AND ACCESSIBILITY. George Okeyo , Andre Bazzone, Maria Barthmes, Rocco Zerlotti, Cecilia George, Niels Fertig 1938-Pos Board B343 CRYO-EM STRUCTURE DETERMINATION OF THE HUMAN REDUCED FOLATE CARRIER SLC19A1 IN COMPLEX WITH METHOTREXATE. Nicholas J. Wright , Justin G. Fedor, Han Zhang, Pyeonghwa Jeong, Yang Suo, Jiho Yoo, Jiyong Hong, Wonpil Im, Seok-Yong Lee 1939-Pos Board B344 METHOTREXATE RECOGNITION BY THE HUMAN REDUCED FOLATE CAR RIER SLC19A1. Justin G. Fedor , Nicholas J. Wright, Han Zhang, Pyeong hwa Jeong, Yang Suo, Jiho Yoo, Jiyong Hong, Wonpil Im, Seok-Yong Lee 1940-Pos Board B345 RESIDUES INVOLVED IN PROTON-COUPLED TRANSPORT OF ANTIMALAR IAL DRUGS BY PFCRT. Ali Rasouli , Shashank Pant, Jonathan Kim, Filippo Mancia, Emad Tajkhorshid 1941-Pos Board B346 PHYLOGENETIC AND LOCALISATION ANALYSES OF MAMMALIAN VNUT REVEAL A UNIQUE ER-RETENTION SEQUENCE REPLACES VESICULAR TAR GETING MOTIFS IN THE C-TERMINUS. Stephanie Rayner , Gaby Jensen, Lara Gastaldello, Damon Poburko

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