Biophysical Society 67th Annual Meeting Program Guide

No Abstract 11:45 am IN-CELL PROTEIN FOOTRPRINTING COUPLED TO MASS SPECTROMETRY TO STUDY PROTEIN INTERACTIONS IN COMPLEX MODEL SYSTEMS. Lisa M. Jones No Abstract 12:15 pm MULTIMODAL PRECISION MEASUREMENT OF SINGLE CELLS. Aaron Streets Platform DNA Structure and Dynamics 10:45 am - 12:45 pm, Room 6D Co-Chairs Lu Bai, Penn State University, USA Xinyu A. Feng, Johns Hopkins University, USA 10:45 am LONG RANGE CHROMOSOMAL INTERACTIONS AND FIRST PASSAGE PRO CESS IN BUDDING YEAST. Lu Bai 91-plat 11:00 am TRANSCRIPTION-INDUCED ACTIVE FORCES SUPPRESS CHROMATIN MO TION BY INDUCING A TRANSIENT DISORDER-TO-ORDER TRANSITION. Sucheol Shin , Hyun Woo Cho, Guang Shi, Dave Thirumalai 92-plat 11:15 am ROLE OF DNA SLIDING FRICTION AND NON-EQUILIBRIUM DYNAMICS IN VIRAL DNA EJECTION AND PACKAGING. Mounir Fizari , Paul Jardine, Douglas E. Smith 93-plat 11:30 am DYNAMIC CONCATENATION LEADS TO ANOMALOUS TRANSPORT OF RING DNA IN CONCENTRATED SOLUTIONS. Juexin Marfai , Philip Neill, Ryan McGorty, Rae Robertson-Anderson 94-plat 11:45 am DYNAMIC SELF-ORGANIZATION OF THE HUMAN GENOME DURING THE CELL CYCLE. Suho Lee , Alexandra Zidovska 95-plat 12:00 pm DNA BINDING DYNAMICS AND TARGET LOCATION MECHANISM OF PIO NEER FACTOR GAF. Xinyu A. Feng , Kaitlin M. Ness, Celina Liu, Carl Wu, Taekjip Ha 96-plat 12:15 pm FROM SINGLE-MOLECULE TO SYNCHROTRON: NEW TOOLS FOR INVESTI GATING THE MOLECULAR MECHANISMS OF ABERRANT DNA DISEASES. Alice V. Rhind-Tutt , Sophie E. Fountain, Mahmoud A. Abdelhamid, Timothy D. Craggs 97-plat 12:30 pm INTERPHASE CHROMOSOMES OF THE AEDES AEGYPTI MOSQUITO ARE LIQUID CRYSTALLINE AND CAN SENSE MECHANICAL CUES. Vinicius G. Contessoto , Olga Dudchenko, Erez Aiden, Peter G. Wolynes, Jose N. Onuchic, Michele Di Pierro Platform Protein-Small Molecule Interactions 10:45 am - 12:45 pm, Room 6E Co-Chairs Efthymios Kyriakis, University of British Columbia, Canada Anna Pavlova, Georgia Institute of Technology, USA 10:45 am PREDICTING THE MECHANISM OF ACTIONS OF CAPSID ASSEMBLY MODULATORS FROM A COMBINATION OF MOLECULAR DYNAMICS AND MACHINE LEARNING. Anna Pavlova , Zixing Fan, Diane L. Lynch, James C. Gumbart 90-plat 98-plat

99-plat 11:00 am HOW DOES A LIGAND EXIT FROM A BURIED RECEPTOR CAVITY? ATOMIS TIC SIMULATIONS OF UNBINDING PATHWAYS WITH RIGOROUS KINETICS. Marion L. Silvestrini , Riccardo Solazzo, Matteo Masetti, Kevin H. Gardner, Lillian T. Chong 100-plat 11:15 am THE EFFECT OF PFAS ON PPAR-GAMMA/RXR-ALPHA HETERODIMER. Semiha Kevser Bali , Nuno M. Almeida, Deepak James, Arohi Nair, Angela 11:30 am MOLECULAR FINGERPRINT IN HYALURONAN-PEPTIDE INTERACTIONS: COOPERATION OF ELECTROSTATICS AND SIDE-CHAIN SPECIFICITY IN EN HANCED ARGININE EFFECT. Miguel Riopedre Fernández , Denys Biriukov, Martin Dračínský, Hector Martinez-Seara 102-plat 11:45 am MOLECULAR EVOLUTION OF EXTENDED SPECTRUM BETA-LACTAM RE SISTANCE. Ilona K. Gaszek , Isik Kantarcioglu, M. Sadik Yildiz, Levent Sari, Ayesha Ahmed, Alan Katz, Milo M. Lin, Erdal Toprak 103-plat 12:00 pm VARIED MECHANISMS FOR THE NEUTRALIZATION OF BIOLOGICAL TOXINS USING NATURAL PRODUCTS. Ryan Limbocker , Justus Gabriel, Thomas Tan, Dillon J. Rinauro, Michele Vendruscolo 104-plat 12:15 pm Travel Award Winner STRUCTURAL INSIGHTS FOR THE MODULATION OF KCNQ1 CHANNEL BY ML277. Efthymios Kyriakis , Jodene Eldstrom, Katrien Willegems, Fariba Ataei, Harutyun Sahakyan, Ying Dou, Sophia Russo, Filip Van Petegem, David Fedida 105-plat 12:30 pm UNRAVELING THE MOLECULAR MECHANISM OF TYPE II TOPOISOMERASE POISONS WITH MAGNETIC TWEEZERS. Ian L. Morgan , Keir C. Neuman Platform K. Wilson 101-plat 106-plat 10:45 am THE ELECTROMECHANICS OF LIPID MEMBRANES: A DIMENSIONALLY REDUCED THEORY. Yannick Azhri Din Omar , Zachary G. Lipel, Kranthi K. Mandadapu 107-plat 11:00 am TOPOLOGICAL LEARNING APPROACH TO CHARACTERIZE LIPIDS. Andres S. Arango , Hyun Park, Emad Tajkhorshid 108-plat 11:15 am INVESTIGATING THE ORGANISATION OF THE ASYMMETRIC PLASMA MEMBRANE USING A NOVEL SOLVATOCHROMIC REPORTER. Chandrima Patra , Maninder Singh, Thomas V. Zanten, Parvinder Pal Singh, Satyajit Mayor 109-plat 11:30 am NANOSCALE MEMBRANE DYNAMICS IN CHAIN ASYMMETRIC LIPID BILAY ERS. Elizabeth G. Kelley , Moritz P.K. Frewein, Georg Pabst, Michihiro Nagao 110-plat 11:45 am LIPID SCRAMBLING FACILITATES MEMBRANE VESICULATION THROUGH DECREASING MEMBRANE STIFFNESS. Hongyin Wang , Kandice R. Leven tal, Joseph H. Lorent, Adhvikaa A. Revathi, Ilya Levental Membrane Dynamics 10:45 am - 12:45 pm, Room 6F Co-Chairs Rana Ashkar, Virginia Tech, USA Georg Pabst, University of Graz, Austria

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