Biophysical Society 67th Annual Meeting Program Guide

83-symp 11:15 am APPLYING AI METHODS TO PROTEIN BIOLOGY. Kathryn Tunyasuvunakool 84-symp 11:45 am MEGA-SCALE ANALYSIS OF PROTEIN FOLDING STABILITY IN BIOLOGY AND PROTEIN DESIGN. Gabriel J. Rocklin , Kotaro Tsuboyama 85-symp 12:15 pm COMPUTATIONAL STRUCTURAL BIOLOGY IN THE ERA OF DEEP LEARNING. John Moult Symposium Optogenetics and Beyond 10:45 am - 12:45 pm, Room 6B Chair Mikhail Shapiro, California Institute of Technology, USA 86 -symp 10:45 am DIVERSITY AND MOLECULAR MECHANISMS OF CHANNELRHODOPSINS. Elena G. Govorunova , Oleg A. Sineshchekov, Hai Li, John L. Spudich 87-symp 11:15 am LEVERAGING OPTOGENETICS FOR CRISPRI SCREENS IN HUMAN IPSC CARDIOMYOCYTES. Emilia Entcheva , Julie Han 88 -symp 11:45 am LIGHT-GUIDED EMBRYOGENESIS: USING OPTOGENETICS TO PROBE AND REPLACE DEVELOPMENTAL SIGNALING PATTERNS. Jared E. Toettcher 89-symp 12:15 pm BIOMOLECULAR ULTRASOUND FOR NONINVASIVE IMAGING AND CON TROL OF CELLULAR FUNCTION. Mikhail G. Shapiro Symposium Black in Biophysics: The Next Generation 10:45 am - 12:45 pm, Room 6C The Biophysical Society (BPS) has been a change agent for members of groups historically underrepresented in the physical and life sciences, women, and international scientists. We serve all members and our ef forts to mentor and promote the careers of rising scientists underscores our belief that diversity will be enhanced if we invest in the next genera tion. In this President’s Symposium at the BPS Annual Meeting, we are taking the opportunity to highlight Black scientists and honor Black History Month in the U.S. and elsewhere. At our annual meeting, BPS aims to foster inclusion and the momentum inspired by the Black Lives Matter movement. Featured are four stars from different fields, selected to attract a broad, interdisciplinary audience from across our Society. We invite all attendees to learn about exciting new developments in biophysics and celebrate diversity at this special symposium. Co-chairs Bil Clemons, California Institute of Technology, USA Theanne Griffith, University of California, Davis, USA No Abstract 10:45 am MICROENVIRONMENT REGULATION OF METASTASIS. Kandice Tanner No Abstract 11:15 am COMPUTATIONAL APPROACHES FOR UNDERSTANDING AND ENGINEER ING BIOMOLECULAR CONDENSATES. Jerelle A. Joseph

We will present applications of the NextGen-O2k and O2k-FluoRespirom eter to explore mitochondrial physiology and pathology in various types of samples and find solutions to mitochondria-associated diseases. Speaker Erich Gnaiger, Founder & CEO, Oroboros Instruments GmbH Exhibits 10:00 am - 5:00 pm, Exhibit Hall BC Take this opportunity to meet editors of Biophysical Journal . Editors will be available to talk about the journal and answer questions about where you should submit your work, what will help to get your work published, and what you can expect when you submit. Editor-in-Chief Vasanthi Jayaraman and other editors will be present at the Biophysical Society publications booth. Coffee Break 10:15 am - 11:00 am, Exhibit Hall BC Exhibitor Presentation Carl Zeiss Microscopy LLC 10:30 am - 12:00 pm, Room 10 Discover How Accessible Lattice Light Sheet Technology and Image Analysis Really are with ZEISS Lattice Lightsheet 7 In order to best understand the world around us it is necessary to observe microscopic specimens in as natural a state as possible. This requires a transition from imaging fixed to live specimens and expand ing from 2D to 3D model organisms. The drive towards live-cell imaging over long timeframes and at high volume speeds brings new challenges. There is evidence that traditional imaging techniques can influence the behavior of specimens due to phototoxicity, thus affecting the integrity of the results, and with the push to perform long-term volumetric imaging comes a need to analyze increasingly larger data sets. This talk will describe how ZEISS Lattice Lightsheet 7 makes long-term volumetric imaging of living cells with subcellular resolution possible without having to change your standard sample preparation protocols to accommodate the instrument. With automatic alignment and easy acquisition workflows, lattice light-sheet imaging is now as accessible as using a standard inverted microscope. ZEISS ZEN microscopy software and arivis Vision4D provide analysis pipelines which can easily be utilized to go from large image datasets to results. Join us for this presentation to learn how accessible lattice light sheet technology and image analysis really are with ZEISS Lattice Lightsheet 7, ZEN microscopy software and arivis Vision 4D. Speaker Renée Dalrymple, Life Science Business Sector Marketing Manager, Carl Zeiss Microscopy LLC Symposium Meet the Editors, Biophysical Journal 10:15 am - 11:00 am, Lobby BC/Publications Booth

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Predicting Protein Fold 10:45 am - 12:45 pm, Room 6A

Chair John Moult, University of Maryland, USA 82-symp 10:45 am MEMBRANE PROTEIN STRUCTURAL SYMMETRY AND ASSEMBLY PAT TERNS. Lucy R. Forrest

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