Biophysical Society 67th Annual Meeting Program Guide

303-pos Board B124 INTRICATE COUPLING BETWEEN THE TRANSACTIVATION AND BASIC LEUCINE ZIPPER DOMAINS GOVERNS PHOSPHORYLATION OF TRANSCRIP TION FACTOR ATF4 BY CASEIN KINASE 2. Steven Siang 304-pos Board B125 ELUCIDATING THE MECHANISM OF MBD PROTEIN LLPS AND ITS ROLE IN HETEROCHROMATIN FORMATION AND TRANSCRIPTIONAL REPRES SION. Nicole Maurici , Catherine Campbell, Jessica L. Henty-Ridilla, Alaji Bah 305-pos Board B126 INTRAMOLECULAR AND INTERMOLECULAR EFFECTS OF AROMATIC STICKER RESIDUE STRENGTH ON INTRINSICALLY DISORDERED PROTEIN REGIONS. David Moses , Garrett M. Ginell, Alex S. Holehouse, Shahar Board B127 FULL ACTIVATION OF WASP, NOT N-WASP, BY CDC42 AND PIP 2 REQUIRES CDC42 PRENYLATION. Souvik Dey , Huan-Xiang Zhou 307-pos Board B128 LINKING STRUCTURAL CHANGES WITH DESICCATION PROTECTION OF INTRINSICALLY DISORDERED PROTEINS. Edith R. Gollub , Shraddha KC, Feng Yu, Thomas C. Boothby, Shahar Sukenik 308-pos Board B129 BEYOND DISORDER: AN INTEGRATIVE INVESTIGATION OF THE INTRINSI CALLY DISORDERED PROTEIN 4E-BP2. Thomas E. Tsangaris , Spencer Smyth, Greg W. Gomes, Julie D. Forman-Kay, Claudiu C. Gradinaru 309-pos Board B130 PROLINE ISOMERIZATION COMPENSATES FOR THE EFFECT OF PHOS PHORYLATION IN CONFORMATIONS OF THE DISORDERED RNA POLY MERASE II CTD. Raymond B. East , Lizbeth Mendoza, Scott A. Showalter, Wei Chen, K. Aurelia Ball 310-pos Board B131 FLEXIBILITY OF THE HIV VIF-A3F BINDING INTERACTION. Elizabeth Miller , Juan Alcantara, K. Aurelia Ball 311-pos Board B132 CYCLIC-NDGA EFFECTIVELY INHIBITS HUMAN GAMMA-SYNUCLEIN FIBRILLATION, FORMS OFF-PATHWAY SPECIES, AND DISINTEGRATES PRE FORMED MATURE FIBRILS. Sneh Lata Singh , Rajiv Bhat 312-pos Board B133 CONTROLLING HTT PROTEIN AGGREGATION TO ASSESS TOXICITY IN CAE NORHABDITIS ELEGANS. Ephraim C. Ezeigbo , Justin A. Legleiter 313-pos Board B134 OBTENTION OF ACCURATE ABETA-ZN(II) ENSEMBLES FROMMOLECULAR MODELLING AND BAYESIAN/MAXIMUM ENTROPY REWEIGHING. Julen Aduriz 314-pos Board B135 DYNAMICS OF TERNARY COMPLEX FORMATION OF AN IDP AND TWO BINDING PARTNERS AND THEIR ALLOSTERIC EFFECTS STUDIED BY THREE COLOR SINGLE-MOLECULE FRET. Jae-Yeol Kim , Hoi Sung Chung 315-pos Board B136 THERMODYNAMICS OF E.COLI SSB PHASE SEPARATION. EFFECTS OF MONOVALENT SALT CONCENTRATION AND TYPE AND INTRINSICALLY DIS ORDERED LINKER MODIFICATIONS. Alexander G. Kozlov , Irina A. Shkel, M. Thomas Record, Timothy M. Lohman 316-pos Board B137 EFFECTS OF PHOSPHORYLATION TO THE CONFORMATIONAL SPACE OF C-TERMINAL DOMAIN OF RNA POLYMERASE II. Weththasinghage Don Amith , Bercem Dutagaci Sukenik 306-pos

289-pos Board B110 MEMBRANE CURVATURE GOVERNS THE DISTRIBUTION OF PIEZO1 IN LIVE CELLS. Shilong Yang , Xinwen Miao, Steven Arnold, Boxuan Li, Alan Ly, Huan Wang, MatthewWang, Xiangfu Guo, Medha M. Pathak, Wenting Zhao, Charles D. Cox, Zheng Shi 290-pos Board B111 MOLECULAR MECHANISM OF CORE PLANAR CELL POLARITY COMPLEX FUNCTION ELUCIDATED WITH SINGLE-MOLECULE METHODS. Silas Boye Nissen , Alexis T. Weiner, Alexander R. Dunn, Jeffrey D. Axelrod 291-pos Board B112 Travel Award Winner EFFLUX OF ANTIBIOTICS BY THE HOMOTRIMERIC TOLC TRANSMEM BRANE PROTEIN. Isik Kantarcioglu , Ilona K. Gaszek, Erdal Toprak, Ali Rana Atilgan, Canan Atilgan 292-pos Board B113 EXPLORING CONFORMATIONAL TRANSITIONS IN MEMBRANE PROTEINS WITH MEMENTO. Simon Lichtinger, Simon Newstead, Philip C. Biggin Intrinsically Disordered Proteins I (Boards B114 - B138) 293-pos Board B114 DISORDERED PROTEINS AND BAR DOMAINS COLLABORATE TO REMODEL MEMBRANES. Caleb Walker , Wilton T. Snead, Wade F. Zeno, Liping Wang, Eileen M. Lafer, Jeanne C. Stachowiak 294-pos Board B115 COARSE-GRAINED INTRINSICALLY DISORDERED PROTEIN SIMULA TIONS WITH EXPLICIT IONS PARAMETERIZED BY SALTING-OUT CON STANTS. Thomas P. Dannenhoffer-Lafage , Robert B. Best 295-pos Board B116 A DEEP DIVE INTO BIOMOLECULAR CONDENSATES USING SINGLE-DROP LET SURFACE-ENHANCED RAMAN SPECTROSCOPY. Samrat Mukhopadhy ay , Anamika Avni, Ashish Joshi, Anuja Walimbe, Swastik G. Pattanashetty 296-pos Board B117 UNCOVERING THE CONDITIONS THAT DICTATE THE LIQUID-LIQUID PHASE SEPARATION OF THE CTD OF RNAPII. Nathan McKean 297-pos Board B118 LIPID DROPLETS AS FLEXIBLE SUBSTRATES FOR PROTEIN PHASE SEPARA TION. Advika Kamatar , Jeanne C. Stachowiak, Sapun H. Parekh 298-pos Board B119 COMPUTATIONAL MODULE OF NANODROPLET FORMATION EN ROUTE TO FIBRILLIZATION OF AMYLOID PEPTIDES WITH DESIGNED FLANKING SEQUENCES. Zhenzhen Zhang , Feng Ding 299-pos Board B120 CONNECTING SEQUENCE FEATURES WITHIN THE DISORDERED C-TER MINAL LINKER OF B. SUBTILIS FTSZ TO FUNCTIONS AND BACTERIAL CELL DIVISION. Min Kyung Shinn , Megan Cohan, Jessie L. Bullock, Kiersten Ruff, Petra Anne Levin, Rohit V. Pappu 300-pos Board B121 Travel Award Winner RAPID PREDICTION AND ANALYSIS OF PROTEIN INTRINSIC DISORDER. Guy W. Dayhoff , Vladimir N. Uversky 301-pos Board B122 SH3 BINDING PATHWAY AND KINETICS IN THE PRESENCE. Frida Anguiano , Oluebube Onwuzulu, Anna Carhart, Elliott J. Stollar, K. Aurelia Ball 302-pos Board B123 EFFECTS OF A KEY NEGATIVELY CHARGED RESIDUE MUTATION ON THE BINDING PATHWAY OF SH3 DOMAIN COMPLEX AND ARKA PEPTIDE. Oluebube C. Onwuzulu

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