Biophysical Society 67th Annual Meeting Program Guide

317-pos Board B138 TRANSCRIPTION ACTIVATION DOMAIN STRUCTURE CORRELATES WITH GENE EXPRESSION LEVELS. Eduardo Flores , Max V. Staller, Shahar Sukenik Condensates: Physical Properties and Modeling I (Boards B139 - B157) 318-pos Board B139 LATERAL COMPRESSION OF LIPIDS DRIVES TRANSBILAYER COUPLING OF PROTEIN CONDENSATES. Yohan Lee , Sujin Park, Feng Yuan, Jeanne C. Stachowiak 319-pos Board B140 Travel Award Winner CONDENSATE’S AGEING MODELLED THROUGH MOLECULAR DYNAMICS: PROTEIN STRUCTURAL TRANSITIONS CRITICALLY TRANSFORM THE NET WORK CONNECTIVITY AND VISCOELASTICITY OF RNA-BINDING PROTEIN CONDENSATES. Ignacio Sanchez Burgos , Andres R. Tejedor, Maria Espi nosa, Jorge Ramirez, Rosana Collepardo-Guevara, Jorge R. Espinosa 320-pos Board B141 PROTEIN-RNA CONDENSATES: COMPLEMENTARY OR COMPETING INTER ACTIONS IN ALS PROGRESSION? Mark D. Driver , Jasper Postema, Patrick Board B142 THE CONCENTRATION THRESHOLD FOR CONDENSATION OF MULTIVA LENT MOLECULES IS SET BY THE MAXIMUM SOLUBILITY PRODUCT. An iruddha Chattaraj, Leslie M. Loew 322-pos Board B143 COARSE-GRAINDED MODEL FOR SIMULATING PROTEIN COMPLEXES: FOLDED VS. DISORDERED PROTEINS. Youngchan Kim , Jeetain Mittal 323-pos Board B144 PHASE SEPARATION AND GELATION OF CHEMICALLY REACTIVE MACRO MOLECULES. Ruoyao Zhang , Sheng Mao, Mikko P. Haataja 324-pos Board B145 PREDICTING MORPHOLOGIES OF BIOMOLECULAR CONDENSATES FROM PROTEIN INTERACTION NETWORKS. Tianhao Li , WilliamM. Jacobs 325-pos Board B146 FIELD-THEORETIC FORMULATION FOR PHASE BEHAVIORS OF 20-AMINO ACID-TYPE INTRINSICALLY DISORDERED PROTEIN SEQUENCES. Jonas Wessén , Tanmoy Pal, Suman Das, Hue Sun Chan 326-pos Board B147 MEMBRANE REMODELING AND VESICLE FORMATION BY BIOMOLECU LAR CONDENSATES: A COARSE GRAINED SIMULATION STUDY. Sayantan Mondal , Qiang Cui 327-pos Board B148 REGULATION OF EGFR PHASE TRANSITION THROUGH GRB2-GRB2 INTERACTIONS. Henry T. Phan , Chun-Wei Lin, Brittany Stinger, Joseph B. DeGrandchamp, Lap Jung Nugent Lew, Jay T. Groves 328-pos Board B149 MULTI-SPECIES PHASE SEPARATION OF INTRINSICALLY DISORDERED PRO TEINS IN ANALYTICAL AND FIELD-THEORETIC MODELS. Tanmoy Pal , Jonas Wessén, Suman Das, Yi-Hsuan Lin, Hue Sun Chan 329-pos Board B150 FLUCTUATING DIFFUSIVITY OF INTRINSICALLY DISORDERED PROTEINS. Eiji Yamamoto , Fuga Watanabe, Robert B. Best, Takuma Akimoto, Kresten Lindorff-Larsen, Ralf Metzler 330-pos Board B151 INVESTIGATE PARTITIONING OF DRUG MOLECULES IN PROTEIN CONDEN SATES USING ATOMISTIC MOLECULAR DYNAMICS SIMULATIONS. Cong Wang , Bin Zhang R. Onck 321-pos

331-pos Board B152 BIOMOLECULAR CONDENSATES UNDER EXTREME MARTIAN SALT CONDI TIONS. Lena Ostermeier , Roland Winter 332-pos Board B153 DESIGNER PROTEINS AS POTENTIAL THERAPEUTIC BIOMOLECULAR CON DENSATES. Tin Long Chris Ng , Mateo Hoare, Timothy Welsh, Sneideris Tomas, Ellis Wilde, Tuomas P.J. Knowles, Laura S. Itzhaki, Janet R. Kumita 333-pos Board B154 Travel Award Winner REVEALING NANOSCALE STRUCTURE AND INTERFACES OF POLYMER AND PROTEIN CONDENSATES VIA CRYO-ELECTRON MICROSCOPY. Aoon Rizvi 334-pos Board B155 INVESTIGATING THE BACTRIA MOTION IN AN ASYMMETRIC RATCHET CHANNEL. Maryam Fathian 335-pos Board B156 RNA STRUCTURE CONTROLS ASSEMBLY OF MULTI-LAYERED PARASPECK LES. Wilton T. Snead , Krishna Shrinivas, Danial Babaki, Kevin M. Weeks, Amy S. Gladfelter 336-pos Board B157 EFFECTS OF ALPHA-SYNUCLEIN AND SYNAPTIC VESICLES ON THE MATE RIAL PROPERTIES OF SYNAPSIN CONDENSATES. Huan Wang , Christian Hoffmann, Jordan Elliott, James Roggeveen, Howard A. Stone, Jean Baum, Dragomir Milovanovic, Zheng Shi Transcription (Boards B158 - B173) 337-pos Board B158 LARGE SCALE DISCOVERY OF REGULATORY ARCHITECTURES IN BACTE RIA. Tom Roeschinger 338-pos Board B159 MODELING AND SIMULATING HUMAN MITOCHONDRIAL RNA POLY MERASE NUCLEOTIDE ADDITION CYCLE USING COMPUTATIONAL MICRO SCOPE. Shannon J. McElhenney , Moises E. Romero, Jin Yu 339-pos Board B160 ANALYSIS OF RNA POLYMERASE II TRIGGER LOOP MUTATIONS USING SIMULATIONS AND MACHINE LEARNING. Bercem Dutagaci , Bingbing Duan, Craig D. Kaplan, Michael Feig 340-pos Board B161 HIGH THROUGHPUT MEASUREMENTS OF DIRECT ACTIVATION DOMAIN COACTIVATOR INTERACTIONS. Nicole DelRosso , Peter Suzuki, Daniel Griffith, Alex S. Holehouse, Lacramioara Bintu, Polly Fordyce 341-pos Board B162 NOVEL IMPROVEMENTS TO RNA SYNTHESIS FOR BIOPHYSICAL STUD IES. Kithmie MalagodaPathiranage, Ruptanu Banerjee, Purnima Mala, Amin Abek, Craig T. Martin 342-pos Board B163 TOWARD MERGING IMAGE ANALYSIS AND GENE NETWORK DISCOVERY FROM FLUORESCENT IN SITU HYBRIDIZATION DATA. Max Schweiger , Zeliha Kilic, Camille Moyer, Sina Jazani, Rory Kruithoff, Alexis Coullomb, Lei Zhou, Douglas P. Shepherd, Steve Pressé 343-pos Board B164 SYNERGY BETWEEN PAUSING AND CLEAVAGE-FACTOR-ASSISTED-PROOF READING RESULTS IN OPTIMAL TRANSCRIPTION SPEED AND TOLERABLE ACCURACY. Tripti Midha , Anatoly B. Kolomeisky, Oleg Igoshin 344-pos Board B165 LOCATION OF A TOPOLOGICALLY ASSOCIATING DOMAIN AT THE NUCLEAR PERIPHERY HAS NO SYSTEMATIC CAUSAL EFFECT ON ITS GENES TRANSCRIPTION LEVELS IN DROSOPHILA NUCLEI. Igor S. Tolokh , Alexan der Y. Afanasyev, Yoonjin Kim, Igor V. Sharakhov, Alexey V. Onufriev

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